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ChemicalBook >> CAS DataBase List >>2'-FLUORO-6'-METHOXYACETOPHENONE

2'-FLUORO-6'-METHOXYACETOPHENONE

2'-FLUORO-6'-METHOXYACETOPHENONE Structure
2'-FLUORO-6'-METHOXYACETOPHENONE structure
CAS No.
120484-50-6
Chemical Name:
2'-FLUORO-6'-METHOXYACETOPHENONE
Synonyms
2-FLUORO-6-METHOXYACETOPHENONE;2'-Fluoro-6'-methoxyacetophenone;1-(2-FLUORO-6-METHOXYPHENYL)ETHANONE;Ethanone, 1-(2-fluoro-6-methoxyphenyl)-;2′-Fluoro-6′-methoxyacetophenone, CAS 120484-50-6
CBNumber:
CB2359807
Molecular Formula:
C9H9FO2
Molecular Weight:
168.16
MDL Number:
MFCD00671762
MOL File:
120484-50-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:40
Product description Number Pack Size Price
1-(2-Fluoro-6-methoxyphenyl)ethanone F593410 5g $525
2'-FLUORO-6'-METHOXYACETOPHENONE 95.00% HCH0019907 2.5G $958.94
2'-Fluoro-6'-methoxyacetophenone PC4586 1g $60
1-(2-Fluoro-6-methoxyphenyl)ethanone Z8240 5g $163
2'-FLUORO-6'-METHOXYACETOPHENONE 95.00% HCH0019907 250MG $131.25
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2'-FLUORO-6'-METHOXYACETOPHENONE Properties

Boiling point 217℃
Density 1.127
refractive index 1.508
Flash point 83℃
storage temp. Sealed in dry,Room Temperature
form liquid
color Clear, lemon/pale amber

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Hazard Note  Irritant
HS Code  2914790090
NFPA 704
1
2 0

2'-FLUORO-6'-METHOXYACETOPHENONE price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F593410 1-(2-Fluoro-6-methoxyphenyl)ethanone 120484-50-6 5g $525 2021-12-16 Buy
American Custom Chemicals Corporation HCH0019907 2'-FLUORO-6'-METHOXYACETOPHENONE 95.00% 120484-50-6 2.5G $958.94 2021-12-16 Buy
Apolloscientific PC4586 2'-Fluoro-6'-methoxyacetophenone 120484-50-6 1g $60 2021-12-16 Buy
AK Scientific Z8240 1-(2-Fluoro-6-methoxyphenyl)ethanone 120484-50-6 5g $163 2021-12-16 Buy
American Custom Chemicals Corporation HCH0019907 2'-FLUORO-6'-METHOXYACETOPHENONE 95.00% 120484-50-6 250MG $131.25 2021-12-16 Buy
Product number Packaging Price Buy
F593410 5g $525 Buy
HCH0019907 2.5G $958.94 Buy
PC4586 1g $60 Buy
Z8240 5g $163 Buy
HCH0019907 250MG $131.25 Buy

2'-FLUORO-6'-METHOXYACETOPHENONE Chemical Properties,Uses,Production

Uses

1-(2-Fluoro-6-methoxyphenyl)ethanone is a useful synthetic intermediate. It is used to prepare spiro[2H-1-benzopyran-2,4''-piperidine] derivatives as glycine transport inhibitors.

Synthesis

1-(2-fluoro-6-methoxyphenyl)ethanol

120484-49-3

2'-FLUORO-6'-METHOXYACETOPHENONE

120484-50-6

General procedure for the synthesis of 2-fluoro-6-methoxyacetophenone from 1-(2-fluoro-6-methoxyphenyl)ethan-1-ol: Pyridinium dichromate (44 g, 0.116 mol) was added to a solution of N,N-dimethylformamide (130 mL) of 1-(2-fluoro-6-methoxyphenyl)ethan-1-ol (13.1 g, 0.077 mol). stirred at room temperature for 12 hours. Upon completion of the reaction, water (300 mL) was added to the reaction mixture, diluted with ethyl acetate and filtered through diatomaceous earth. The organic layer was separated, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 2-fluoro-6-methoxyacetophenone as a brown liquid (9.2 g, 70% yield).1H-NMR (δ ppm, CDCl3, 400 MHz): 7.73 (dd, J = 15.1, 8.4 Hz, 1H), 6.73 (m, 2H), 3.85 (s, 3H), 2.53 (s, 3H), 3.85 (s, 3H), 3.85 (s, 3H), 3.85 (s, 3H). 3H), 2.53 (s, 3H).

References

[1] Journal of the American Chemical Society, 2016, vol. 138, # 5, p. 1486 - 1489
[2] Patent: US2012/289496, 2012, A1. Location in patent: Page/Page column 100
[3] Patent: WO2012/151525, 2012, A1. Location in patent: Page/Page column 101

2'-FLUORO-6'-METHOXYACETOPHENONE Preparation Products And Raw materials

Raw materials

1-(2-fluoro-6-methoxyphenyl)ethanol 2-Fluoro-6-methoxybenzonitrile Pyridinium chlorochromate N,N-Dimethylformamide

Preparation Products

2'-FLUORO-6'-METHOXYACETOPHENONE Suppliers

Global( 90)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471; sales@sarms4muscle.com China 10473 58
Changzhou Anxuan Chemical Co., Ltd 		+86-0519-89882563 +86-18961279162 andy@anxuanchem.com China 4327 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
GLR Innovations 		+91 9891111994 info@glrgroup.in India 4535 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Changzhou Ansciep Chemical Co., Ltd. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
career henan chemical co 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Changzhou Anxuan Chemical Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
GLR Innovations 		58
HANGZHOU LEAP CHEM CO., LTD. 		58

View Lastest Price from 2'-FLUORO-6'-METHOXYACETOPHENONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-FLUORO-6'-METHOXYACETOPHENONE pictures 2020-01-05 2'-FLUORO-6'-METHOXYACETOPHENONE
120484-50-6
 US $9.80 / KG 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co

2'-FLUORO-6'-METHOXYACETOPHENONE Spectrum

2'-FLUORO-6'-METHOXYACETOPHENONE(120484-50-6)1HNMR2'-FLUORO-6'-METHOXYACETOPHENONE(120484-50-6)FT-IR

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2-FLUORO-6-METHOXYACETOPHENONE 1-(2-FLUORO-6-METHOXYPHENYL)ETHANONE Ethanone, 1-(2-fluoro-6-methoxyphenyl)- 2'-Fluoro-6'-methoxyacetophenone 2′-Fluoro-6′-methoxyacetophenone, CAS 120484-50-6 120484-50-6 Aromatic Acetophenones & Derivatives (substituted)