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2'-Fluoro-6'-methoxyacetophenone

2'-Fluoro-6'-methoxyacetophenone Structure
2'-Fluoro-6'-methoxyacetophenone structure
CAS No.
120484-50-6
Chemical Name:
2'-Fluoro-6'-methoxyacetophenone
Synonyms
2-FLUORO-6-METHOXYACETOPHENONE;2'-Fluoro-6'-methoxyacetophenone;1-(2-FLUORO-6-METHOXYPHENYL)ETHANONE;Ethanone, 1-(2-fluoro-6-methoxyphenyl)-;2′-Fluoro-6′-methoxyacetophenone, CAS 120484-50-6
CBNumber:
CB2359807
Molecular Formula:
C9H9FO2
Molecular Weight:
168.16
MDL Number:
MFCD00671762
MOL File:
120484-50-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:38
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2'-Fluoro-6'-methoxyacetophenone Properties

Boiling point 217℃
Density 1.127
refractive index 1.508
Flash point 83℃
storage temp. Sealed in dry,Room Temperature
form liquid
color Clear, lemon/pale amber

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Hazard Note  Irritant
HS Code  2914790090
NFPA 704
1
2 0

2'-Fluoro-6'-methoxyacetophenone price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 276880 1-(2-Fluoro-6-methoxyphenyl)ethanone Asreported 120484-50-6 500mg $375 2026-06-03 Buy
Usbiological 276880 1-(2-Fluoro-6-methoxyphenyl)ethanone Asreported 120484-50-6 1g $531 2026-06-03 Buy
Usbiological 276880 1-(2-Fluoro-6-methoxyphenyl)ethanone Asreported 120484-50-6 2g $729 2026-06-03 Buy
Usbiological 276880 1-(2-Fluoro-6-methoxyphenyl)ethanone Asreported 120484-50-6 5g $1238 2026-06-03 Buy
Usbiological 276880 1-(2-Fluoro-6-methoxyphenyl)ethanone Asreported 120484-50-6 10g $1805 2026-06-03 Buy
Product number Packaging Price Buy
276880 500mg $375 Buy
276880 1g $531 Buy
276880 2g $729 Buy
276880 5g $1238 Buy
276880 10g $1805 Buy

2'-Fluoro-6'-methoxyacetophenone Chemical Properties, Uses, Production

Uses

1-(2-Fluoro-6-methoxyphenyl)ethanone is a useful synthetic intermediate. It is used to prepare spiro[2H-1-benzopyran-2,4''-piperidine] derivatives as glycine transport inhibitors.

Synthesis

1-(2-fluoro-6-methoxyphenyl)ethanol

120484-49-3

2'-FLUORO-6'-METHOXYACETOPHENONE

120484-50-6

General procedure for the synthesis of 2-fluoro-6-methoxyacetophenone from 1-(2-fluoro-6-methoxyphenyl)ethan-1-ol: Pyridinium dichromate (44 g, 0.116 mol) was added to a solution of N,N-dimethylformamide (130 mL) of 1-(2-fluoro-6-methoxyphenyl)ethan-1-ol (13.1 g, 0.077 mol). stirred at room temperature for 12 hours. Upon completion of the reaction, water (300 mL) was added to the reaction mixture, diluted with ethyl acetate and filtered through diatomaceous earth. The organic layer was separated, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 2-fluoro-6-methoxyacetophenone as a brown liquid (9.2 g, 70% yield).1H-NMR (δ ppm, CDCl3, 400 MHz): 7.73 (dd, J = 15.1, 8.4 Hz, 1H), 6.73 (m, 2H), 3.85 (s, 3H), 2.53 (s, 3H), 3.85 (s, 3H), 3.85 (s, 3H), 3.85 (s, 3H). 3H), 2.53 (s, 3H).

References

[1] Journal of the American Chemical Society, 2016, vol. 138, # 5, p. 1486 - 1489
[2] Patent: US2012/289496, 2012, A1. Location in patent: Page/Page column 100
[3] Patent: WO2012/151525, 2012, A1. Location in patent: Page/Page column 101

2'-Fluoro-6'-methoxyacetophenone Preparation Products And Raw materials

Raw materials

1-(2-fluoro-6-methoxyphenyl)ethanol 2-Fluoro-6-methoxybenzonitrile Pyridinium chlorochromate N,N-Dimethylformamide

Preparation Products

2'-Fluoro-6'-methoxyacetophenone Suppliers

Global Suppliers ( 92)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Tianjin Ji Ping Jia Chemical Co., Ltd. 18622448868 jpjchem@163.com China 489 62
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Adamas Reagent, Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
Syntechem Co.,Ltd 57
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Tianjin Ji Ping Jia Chemical Co., Ltd. 62

View Latest Price from 2'-Fluoro-6'-methoxyacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-FLUORO-6'-METHOXYACETOPHENONE pictures 2020-01-05 2'-FLUORO-6'-METHOXYACETOPHENONE
120484-50-6
 $9.80 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co

2'-Fluoro-6'-methoxyacetophenone Spectrum

2'-FLUORO-6'-METHOXYACETOPHENONE(120484-50-6)1HNMR2'-FLUORO-6'-METHOXYACETOPHENONE(120484-50-6)FT-IR

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2-FLUORO-6-METHOXYACETOPHENONE 1-(2-FLUORO-6-METHOXYPHENYL)ETHANONE Ethanone, 1-(2-fluoro-6-methoxyphenyl)- 2'-Fluoro-6'-methoxyacetophenone 2′-Fluoro-6′-methoxyacetophenone, CAS 120484-50-6 120484-50-6 Aromatic Acetophenones & Derivatives (substituted)