Naphazoline
- CAS No.
- 835-31-4
- Chemical Name:
- Naphazoline
- Synonyms
- NAPHAZOLINE HCL;NAFAZOLINE;Naphazoline-d4;2-(1-NAPHTHYLMETHYL)-2-IMIDAZOLINE HYDROCHLORIDE;Antan;Imidin;Privine;Sanorin;Rhinazine;ciba2020/r
- CBNumber:
- CB2414016
- Molecular Formula:
- C14H14N2
- Molecular Weight:
- 210.27
- MDL Number:
- MFCD00066737
- MOL File:
- 835-31-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Naphazoline 99.79%(Mayvarybetweenbatches) | orb1306358 | 5mg | $80 |
| Naphazoline 99.79%(Mayvarybetweenbatches) | orb1306358 | 10mg | $100 |
| Naphazoline 99.79%(Mayvarybetweenbatches) | orb1306358 | 25mg | $140 |
| Naphazoline 99.79%(Mayvarybetweenbatches) | orb1306358 | 50mg | $180 |
| Naphazoline 99.79%(Mayvarybetweenbatches) | orb1306358 | 100mg | $240 |
| More product size | |||
| Melting point | 254 °C |
|---|---|
| Boiling point | 339.81°C (rough estimate) |
| Density | 1.1063 (rough estimate) |
| refractive index | 1.6180 (estimate) |
| storage temp. | 2-8°C |
| pka | pKa 10.35 ± 0.02(H2O,t =25,Iundefined) (Uncertain) |
| form | Solid |
| color | White to light yellow |
| CAS DataBase Reference | 835-31-4(CAS DataBase Reference) |
| EWG's Food Scores | 1-3 |
| FDA UNII | H231GF11BV |
| ATC code | R01AA08,R01AB02,S01GA01,S01GA51 |
| NIST Chemistry Reference | Naphazoline(835-31-4) |
Naphazoline price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb1306358 | Naphazoline 99.79%(Mayvarybetweenbatches) | 835-31-4 | 5mg | $80 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1306358 | Naphazoline 99.79%(Mayvarybetweenbatches) | 835-31-4 | 10mg | $100 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1306358 | Naphazoline 99.79%(Mayvarybetweenbatches) | 835-31-4 | 25mg | $140 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1306358 | Naphazoline 99.79%(Mayvarybetweenbatches) | 835-31-4 | 50mg | $180 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1306358 | Naphazoline 99.79%(Mayvarybetweenbatches) | 835-31-4 | 100mg | $240 | 2026-05-06 | Buy |
Naphazoline Chemical Properties,Uses,Production
Originator
Privine,Ciba,US,1942
Uses
Adrenergic (vasoconstrictor).
Uses
Naphazoline is used in severe rhinitis associated with colds, allergic reactions, and severe and chronic inflammatory conditions, in particular for inflammation of the antrum of Highmore as well as for stopping nosebleeds.
Definition
ChEBI: 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole is a member of naphthalenes.
Manufacturing Process
2.7 parts of naphthyl-(1)-acetiminoethylether hydrochloride of the formula (produced from naphthyl-(1)-acetonitrile and methanol) are dissolved in 12 parts of absolute alcohol. 1 part of ethylenediamine is then added and the whole is heated to gentle boiling while passing nitrogen through it and simultaneously stirring until ammonia escapes no longer. The alcohol is then distilled and the residue mixed with 40 parts of benzene and 1.8 parts of caustic potash. Stirring is continued for some time whereby the imidazoline base is dissolved in benzene. The benzene residue is recrystallized several times from toluene.
brand name
Albalon (Allergan); Nafazair (Bausch & Lomb); Nafazair (Pharmafair); Naphcon (Alcon); Opcon (Bausch & Lomb); Vasocon (Novartis).
Therapeutic Function
Nasal decongestant
Synthesis
Naphazoline, 2-(1-naphthylmethyl)-2-imidazoline (11.1.36), is synthesized from (1-naphthyl)acetonitrile, which upon reaction with ethanol transforms into iminoester (11.1.35), and undergoes further heterocyclization into the desired imidozoline derivative (11.1.36) upon reaction with ethylendiamine [40].
Naphazoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15074 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5983 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| Zhuoer Chemical Co., Ltd | 02120970332; +8613524231522 | sales@zhuoerchem.com | China | 2904 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
View Lastest Price from Naphazoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-29 | Naphazoline
835-31-4
|
1kg | 99% | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-11 | Naphazoline
835-31-4
|
$40.00-93.00 | 99.79% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-08-31 | naphazoline
835-31-4
|
$50.00 | 1KG | 99% | 500tons/month | Hubei Aumei New Material Co., Ltd. |
-
- Naphazoline
835-31-4
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Naphazoline
835-31-4
- $40.00-93.00
- 99.79%
- TargetMol Chemicals Inc.
-
- naphazoline
835-31-4
- $50.00
- 99%
- Hubei Aumei New Material Co., Ltd.
