Cytidine 5'-monophosphate disodium salt
- CAS No.
- 6757-06-8
- Chemical Name:
- Cytidine 5'-monophosphate disodium salt
- Synonyms
- CYTIDINE-5'-MONOPHOSPHATE DISODIUM SALT;CMP-2Na;CMP, NA2;5'-CMP 2NA;5'-cmp-na2;C-5μ-P, CMP;CMP DISODIUM SALT;C-5'-P DISODIUM SALT;Cytidine 5'-monophos;Guanosine 5'-cytidine
- CBNumber:
- CB2441544
- Molecular Formula:
- C9H12N3Na2O8P
- Molecular Weight:
- 367.16
- MDL Number:
- MFCD00064355
- MOL File:
- 6757-06-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 300 °C |
|---|---|
| refractive index | 8 ° (C=2, H2O) |
| storage temp. | 2-8°C |
| solubility | water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow |
| form | crystalline |
| color | White |
| biological source | synthetic |
| Water Solubility | water: 100mg/mL, clear to very slightly hazy, colorless to very faintly yellow |
| Cosmetics Ingredients Functions |
HAIR CONDITIONING SKIN CONDITIONING - MISCELLANEOUS |
| InChI | InChI=1/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;/t4-,6-,7-,8-;;/s3 |
| InChIKey | RCIPNLSOCXMZDD-RFFBCSJBNA-N |
| SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,11,r| |
| CAS DataBase Reference | 6757-06-8(CAS DataBase Reference) |
| FDA UNII | 383W8FIS5C |
| UNSPSC Code | 41106305 |
| NACRES | NA.51 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-37/39-36-26 |
| WGK Germany | 3 |
| F | 1-10 |
| HS Code | 29349990 |
| Storage Class | 11 - Combustible Solids |
Cytidine 5'-monophosphate disodium salt price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C1006 | Cytidine 5′-monophosphate disodium salt Sigma Grade, ≥99%, crystalline | 6757-06-8 | 500MG | $60.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | C1006 | Cytidine 5′-monophosphate disodium salt Sigma Grade, ≥99%, crystalline | 6757-06-8 | 1G | $69.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | C1006 | Cytidine 5′-monophosphate disodium salt Sigma Grade, ≥99%, crystalline | 6757-06-8 | 5G | $186 | 2026-04-30 | Buy |
| TCI Chemical | C0524 | Cytidine 5'-Monophosphate Disodium Salt Hydrate >99.0%(HPLC) | 6757-06-8 | 1g | $20 | 2026-04-30 | Buy |
| TCI Chemical | C0524 | Cytidine 5'-Monophosphate Disodium Salt Hydrate >99.0%(HPLC) | 6757-06-8 | 5g | $28 | 2026-04-30 | Buy |
Cytidine 5'-monophosphate disodium salt Chemical Properties, Uses, Production
Uses
Cytidine 5'-Monophosphate Disodium Salt is a salt form of Cytidine 5'-Monophosphate, a constituent of nucleic acids that has been isolated from yeast nucleic acid.
Description
Cytidine 5'-monophosphate disodium salt (5'-CMPNa2) is an organic sodium salt that can be used as a pharmaceutical active ingredient. 5'-CMPNa2 can be used with UMP-Na2, vitamin B6, lipoic acid, and magnesium lactate dihydrate to prepare a capsule-type compound drug for the treatment of polyneuropathy[1].
Chemical Properties
White crystalline powder
Uses
Cytidine 5′-monophosphate disodium salt has been used:
- in nucleotide stock solution
- as an ectonucleotidase (ENTase) inhibitor to probe 5′-ENTase activity in cortical neurons
- in in vitro studies to estimate its effect on growth response of selected bacteria strains that dominate the piglets′ small intestine
Production Methods
The production method of Cytidine 5'-monophosphate disodium salt comprises the following steps: a. adding cytidine, triethyl phosphate and pyridine into a reaction container respectively, and adjusting the reaction temperature to -15-5°C after mixing evenly, and slowly adding a certain amount of phosphorus oxychloride under the temperature condition, and continuing to stir and react for 10-30h after adding; b. taking samples for HPLC analysis, and when the conversion rate is ≥99%, adding 10-15% ice salt water for hydrolysis, and the hydrolysis temperature is controlled to be 0-5°C, and the hydrolysis time is 10-20h; c. after the hydrolysis is completed, standing and stratifying, removing the organic phase, and obtaining a water layer for standby use; d. adjusting the pH of the water layer to 7.0-8.0 with 30% sodium hydroxide, and then dripping 95% alcohol twice the volume of the solution, precipitating crystals, and filtering to obtain a crude product. e. dissolving the crude product, adding activated carbon for decolorization, and continuing to drip 95% alcohol twice the volume of the solution to precipitate crystals, filtering, rinsing, and drying to obtain the finished product Cytidine 5'-monophosphate disodium salt.
Definition
ChEBI: Disodium cytidine 5'-monophosphate is an organic sodium salt that is the disodium salt of CMP. It has a role as a human metabolite. It contains a cytidine 5'-monophosphate(2-).
Biochem/physiol Actions
Cytidine monophosphate(CMP) serve as a nucleotidecarrier for sugars.
References
[1] M. ALMAKAIEV L. S O Bashura. The risk assessment of the combined medicine in the capsule dosage form at the pharmaceutical development stage[J]. News of Pharmacy, 2021. DOI:10.24959/nphj.21.54.
Cytidine 5'-monophosphate disodium salt Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Meiya Pharmaceutical Co.,ltd. | 021-33686691 18001850931 | wangjm@meiyapharm.com | China | 51 | 58 |
| Jiangsu seed Chem Co., Ltd. | 00-13862785 13862785735 | 1968341241@qq.com | China | 51 | 58 |
| Shanghai Richuan Biotechnology Co., Ltd. | 18930985832 | zhangqimeng@nucbiotech.com | China | 40 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Hongene Biotech Corporation | 021-64757213 | info@hongene.com | China | 672 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
Related Questions
Ask a questionView Latest Price from Cytidine 5'-monophosphate disodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-16 | Cytidine 5'-monophosphate disodium salt
6757-06-8
|
1kg | 99%min | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-09-16 | Cytidine 5'-monophosphate disodium salt
6757-06-8
|
1kg | 99%min HPLC | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-09-15 | Cytidine 5'-monophosphate disodium salt (CMP-Na2)
6757-06-8
|
10kg | ≥98% | 2tons | WeiTai BioPharmaceutical Co.,Ltd(Hangzhou) |
-

- Cytidine 5'-monophosphate disodium salt
6757-06-8
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Cytidine 5'-monophosphate disodium salt
6757-06-8
- 99%min HPLC
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Cytidine 5'-monophosphate disodium salt (CMP-Na2)
6757-06-8
- ≥98%
- WeiTai BioPharmaceutical Co.,Ltd(Hangzhou)
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