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(R)-(-)-1-Amino-2-propanol

CAS No.
2799-16-8
Chemical Name:
(R)-(-)-1-Amino-2-propanol
Synonyms
(R)-2-Aminopropan-1-ol;ISOPROPANOLAMINE;(R)-1-AMINO-2-PROPANOL;Isopropanolamin;(-)-ISOPROPANOLAMINE;R-l-Amino-2-propanol;(2R)-1-Amino-2-propanol;(R)-1-Aminopropane-2-ol;(R)-(-)-ISOPROPANOLAMINE;(R)-(-)-1-AMINO-2-PROPANOL
CBNumber:
CB2446594
Molecular Formula:
C3H9NO
Molecular Weight:
75.11
MDL Number:
MFCD00064428
MOL File:
2799-16-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:30:53

(R)-(-)-1-Amino-2-propanol Properties

Melting point 24-26 °C (lit.)
alpha -18 º (c=1.8, H2O)
Boiling point 160 °C (lit.)
Density 0.954 g/mL at 25 °C (lit.)
vapor density 2.6 (vs air)
vapor pressure <1 mm Hg ( 20 °C)
refractive index n20/D 1.4482(lit.)
Flash point 165 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
form Liquid After Melting
pka 12.92±0.35(Predicted)
color Clear colorless to light yellow
Specific Gravity 0.954
optical activity [α]20/D 23.5°, c = 1 in methanol
Water Solubility soluble
Sensitive Hygroscopic
BRN 1718869
InChI 1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3/t3-/m1/s1
InChIKey HXKKHQJGJAFBHI-GSVOUGTGSA-N
SMILES C[C@@H](O)CN
LogP -1.127 (est)
CAS DataBase Reference 2799-16-8(CAS DataBase Reference)
NIST Chemistry Reference 2-Propanol, 1-amino-, (R)-(2799-16-8)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  C
Risk Statements  34
Safety Statements  23-26-36-45
RIDADR  UN 3259 8/PG 2
WGK Germany  1
RTECS  UA5775000
10-34
Autoignition Temperature 635 °F
HazardClass  8
PackingGroup  III
HS Code  29221990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
2
3 0

(R)-(-)-1-Amino-2-propanol price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 238856 (R)-(?)-1-Amino-2-propanol 98% 2799-16-8 1g $38.8 2026-04-30 Buy
Sigma-Aldrich 238856 (R)-(?)-1-Amino-2-propanol 98% 2799-16-8 5g $190 2026-04-30 Buy
TCI Chemical A0974 (R)-(-)-1-Amino-2-propanol >98.0%(GC)(T) 2799-16-8 1g $24 2026-04-30 Buy
TCI Chemical A0974 (R)-(-)-1-Amino-2-propanol >98.0%(GC)(T) 2799-16-8 5g $67 2026-04-30 Buy
Usbiological 241531 (R)-1-Amino-2-propanol 98+% ≥98% 2799-16-8 1g $159 2026-06-03 Buy
Product number Packaging Price Buy
238856 1g $38.8 Buy
238856 5g $190 Buy
A0974 1g $24 Buy
A0974 5g $67 Buy
241531 1g $159 Buy

(R)-(-)-1-Amino-2-propanol Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-1-Amino-2-propanol is a useful research intermediate used in the synthesis of other bioactive small molecules with pharmaceutical applications.

Definition

ChEBI: A 1-aminopropan-2-ol that has R-configuration.

Synthesis

L-Threonine

72-19-5

(R)-(-)-1-Amino-2-propanol

2799-16-8

GENERAL STEPS: Example 2 Synthesis of (R)-1-amino-2-propanol. To a 500 mL reaction vessel was added L-threonine (10 g, 0.839 mol), 2-cyclohexen-1-one (8.07 g, 0.084 mol) and polyethylene glycol. The mixture was stirred under a nitrogen atmosphere at 150-160 °C. After 72 h, the reaction was judged complete when the crystals were completely dissolved and the mixture appeared homogeneous. The yield of (R)-1-amino-2-propanol was confirmed to be 80.6% by gas chromatographic analysis. Subsequently, the reaction solution was distilled under reduced pressure at the same temperature and the fractions were collected at 54-62 °C (1-20 hPa) to give (R)-1-amino-2-propanol (44.4 g, yield: 70.4%, chemical purity: 99.0%, optical purity: 99.9% ee).

References

[1] Chemistry Letters, 1986, p. 893 - 896
[2] Synthetic Communications, 1994, vol. 24, # 10, p. 1381 - 1387
[3] Patent: US2005/222430, 2005, A1. Location in patent: Page/Page column 2
[4] Synthetic Communications, 1993, vol. 23, # 8, p. 1071 - 1074

(R)-(-)-1-Amino-2-propanol Preparation Products And Raw materials

Global( 310)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai KeLy Bio-Pharmaceutical Co., Ltd. 13816253073 lige@kelybiopharm.com China 127 58
Nantong Haigine Pharma Technology Co., Ltd 0513-86266699-8010 19040080082 sales@haigine.com China 71 58
Changzhou Huaren Chemical Co., Ltd 0519-88103998, 13646148298, 88103997, 88122965,88100916 13646148298;051988100916; amy.zhou@huarenchem.com China 51 63
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YICHANG TIANRUI BIOPHARM CO., LTD 13469840438 caiweiguo@renfu.com.cn China 48 58
Beijing Bankchem Pharmatech Co.,Ltd. 010-80236392 17600588818 bankchem@163.com China 247 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
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Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81

View Lastest Price from (R)-(-)-1-Amino-2-propanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-(-)-1-Amino-2-propanol pictures 2022-11-10 (R)-(-)-1-Amino-2-propanol
2799-16-8
25kg 99% 20 tons TAIZHOU DKD CHEMICAL CO., LTD.
(R)-(-)-1-Amino-2-propanol pictures 2019-08-06 (R)-(-)-1-Amino-2-propanol
2799-16-8
$1.00 1KG 95%-99% 2000kg Career Henan Chemical Co
(2R)-1-Amino-2-propanol (R)-1-(Aminomethyl)ethanol (R)-1-Aminopropane-2-ol (2R)-(-)-1-Aminopropan-2-ol (2R)-(-)-2-Hydroxypropylamine, (2R)-(-)-1-Amino-2-hydroxypropane (R)-(-)-1-Amino-2-propanol 98% (R)-(-)-1-Amino-2-propanol (R)-(-)-1-AMINO-2-PROPANOL (R)-(-)-2-HYDROXYPROPYLAMINE (R)-(-)-ISOPROPANOLAMINE (-)-ISOPROPANOLAMINE ISOPROPANOLAMINE (R)-(-)-1-Amino-2-propanol,96% (R)-(-)-1-Amino-2-propanol, 98+% 2-Propanol, 1-amino-, (2R)- Isopropanolamin (R)-(-)-1-AMINO-2-PROPANOL / (R)-(-)-ISOPROPANOLAMINE (R)-(-)-1-Amino-2-propanol > (R)-(-)-1-Amino-2-propanol,>97% China biggest manufacturer (R)-(-)-1-Amino-2-propanol 2799-16-8 (R)-(-)-1-Amino-2-propanol -propanol R-l-Amino-2-propanol (R)-1-AMINO-2-PROPANOL (R)-2-Aminopropan-1-ol 2799-16-8 2799-16-9 C3H9ON C3H10NO CH3CHOHCH2NH2 Chiral Building Blocks Simple Alcohols (Chiral) Chiral Resolution Reagents Asymmetric Synthesis Chiral Resolving Reagents AMINE Simple Alcohols (Chiral) Chiral Building Blocks Synthetic Organic Chemistry Chiral Compound chiral Alcohols and Derivatives Alcohols, Hydroxy Esters and Derivatives Chiral Compounds