(R)-(-)-1-Amino-2-propanol
- CAS No.
- 2799-16-8
- Chemical Name:
- (R)-(-)-1-Amino-2-propanol
- Synonyms
- (R)-2-Aminopropan-1-ol;ISOPROPANOLAMINE;(R)-1-AMINO-2-PROPANOL;Isopropanolamin;(-)-ISOPROPANOLAMINE;R-l-Amino-2-propanol;(2R)-1-Amino-2-propanol;(R)-1-Aminopropane-2-ol;(R)-(-)-ISOPROPANOLAMINE;(R)-(-)-1-AMINO-2-PROPANOL
- CBNumber:
- CB2446594
- Molecular Formula:
- C3H9NO
- Molecular Weight:
- 75.11
- MDL Number:
- MFCD00064428
- MOL File:
- 2799-16-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 24-26 °C (lit.) |
|---|---|
| alpha | -18 º (c=1.8, H2O) |
| Boiling point | 160 °C (lit.) |
| Density | 0.954 g/mL at 25 °C (lit.) |
| vapor density | 2.6 (vs air) |
| vapor pressure | <1 mm Hg ( 20 °C) |
| refractive index |
n |
| Flash point | 165 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | Liquid After Melting |
| pka | 12.92±0.35(Predicted) |
| color | Clear colorless to light yellow |
| Specific Gravity | 0.954 |
| optical activity | [α]20/D 23.5°, c = 1 in methanol |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| BRN | 1718869 |
| InChI | 1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3/t3-/m1/s1 |
| InChIKey | HXKKHQJGJAFBHI-GSVOUGTGSA-N |
| SMILES | C[C@@H](O)CN |
| LogP | -1.127 (est) |
| CAS DataBase Reference | 2799-16-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Propanol, 1-amino-, (R)-(2799-16-8) |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 23-26-36-45 | |||||||||
| RIDADR | UN 3259 8/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | UA5775000 | |||||||||
| F | 10-34 | |||||||||
| Autoignition Temperature | 635 °F | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29221990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Skin Corr. 1B | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
(R)-(-)-1-Amino-2-propanol price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 238856 | (R)-(?)-1-Amino-2-propanol 98% | 2799-16-8 | 1g | $38.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 238856 | (R)-(?)-1-Amino-2-propanol 98% | 2799-16-8 | 5g | $190 | 2026-04-30 | Buy |
| TCI Chemical | A0974 | (R)-(-)-1-Amino-2-propanol >98.0%(GC)(T) | 2799-16-8 | 1g | $24 | 2026-04-30 | Buy |
| TCI Chemical | A0974 | (R)-(-)-1-Amino-2-propanol >98.0%(GC)(T) | 2799-16-8 | 5g | $67 | 2026-04-30 | Buy |
| Usbiological | 241531 | (R)-1-Amino-2-propanol 98+% ≥98% | 2799-16-8 | 1g | $159 | 2026-06-03 | Buy |
(R)-(-)-1-Amino-2-propanol Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liqui
Uses
(R)-(-)-1-Amino-2-propanol is a useful research intermediate used in the synthesis of other bioactive small molecules with pharmaceutical applications.
Definition
ChEBI: A 1-aminopropan-2-ol that has R-configuration.
Synthesis
72-19-5
2799-16-8
GENERAL STEPS: Example 2 Synthesis of (R)-1-amino-2-propanol. To a 500 mL reaction vessel was added L-threonine (10 g, 0.839 mol), 2-cyclohexen-1-one (8.07 g, 0.084 mol) and polyethylene glycol. The mixture was stirred under a nitrogen atmosphere at 150-160 °C. After 72 h, the reaction was judged complete when the crystals were completely dissolved and the mixture appeared homogeneous. The yield of (R)-1-amino-2-propanol was confirmed to be 80.6% by gas chromatographic analysis. Subsequently, the reaction solution was distilled under reduced pressure at the same temperature and the fractions were collected at 54-62 °C (1-20 hPa) to give (R)-1-amino-2-propanol (44.4 g, yield: 70.4%, chemical purity: 99.0%, optical purity: 99.9% ee).
References
[1] Chemistry Letters, 1986, p. 893 - 896
[2] Synthetic Communications, 1994, vol. 24, # 10, p. 1381 - 1387
[3] Patent: US2005/222430, 2005, A1. Location in patent: Page/Page column 2
[4] Synthetic Communications, 1993, vol. 23, # 8, p. 1071 - 1074
(R)-(-)-1-Amino-2-propanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai KeLy Bio-Pharmaceutical Co., Ltd. | 13816253073 | lige@kelybiopharm.com | China | 127 | 58 |
| Nantong Haigine Pharma Technology Co., Ltd | 0513-86266699-8010 19040080082 | sales@haigine.com | China | 71 | 58 |
| Changzhou Huaren Chemical Co., Ltd | 0519-88103998, 13646148298, 88103997, 88122965,88100916 13646148298;051988100916; | amy.zhou@huarenchem.com | China | 51 | 63 |
| Hebei Boxin Biotechnology Co. , Ltd. | 19131160546 | 2681315246@qq.com | China | 13193 | 58 |
| YICHANG TIANRUI BIOPHARM CO., LTD | 13469840438 | caiweiguo@renfu.com.cn | China | 48 | 58 |
| Beijing Bankchem Pharmatech Co.,Ltd. | 010-80236392 17600588818 | bankchem@163.com | China | 247 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Lastest Price from (R)-(-)-1-Amino-2-propanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2022-11-10 | (R)-(-)-1-Amino-2-propanol
2799-16-8
|
25kg | 99% | 20 tons | TAIZHOU DKD CHEMICAL CO., LTD. | ||
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2019-08-06 | (R)-(-)-1-Amino-2-propanol
2799-16-8
|
$1.00 | 1KG | 95%-99% | 2000kg | Career Henan Chemical Co |
-

- (R)-(-)-1-Amino-2-propanol
2799-16-8
- $0.00
- 99%
- TAIZHOU DKD CHEMICAL CO., LTD.
-

- (R)-(-)-1-Amino-2-propanol
2799-16-8
- $1.00
- 95%-99%
- Career Henan Chemical Co
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