3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
- CAS No.
- 100202-39-9
- Chemical Name:
- 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
- Synonyms
- Methyl azetidine-3-carboxylate hydrochloride;Azetidine-3-carboxylic methyl ester hrdrochloride;3-Azetidinecarboxylic acid, methyl ester, hydrochloride (1:1) CAS_EXAMPLE;Methyl azetidine-3-carbox...;methyl azetidine-3-carboxylate HCl;Methyl 3-Azetidine carboxylate HCl;AZETIDINE-3-CARBOXYLIC METHYL ESTER HCL;3-AZETIDINECARBOXYLIC ACID, MEHYDROCHLORIDE;3-Azetidinecarboxylic acid methyl ester HCl;AZETIDINE-3-CARBOXYLIC ACID METHYL ESTER HCL
- CBNumber:
- CB2494090
- Molecular Formula:
- C5H10ClNO2
- Molecular Weight:
- 151.59
- MDL Number:
- MFCD01861758
- MOL File:
- 100202-39-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Methyl Azetidine-3-carboxylate Hydrochloride >98.0%(T) | M2521 | 1g | $48 |
| Methyl Azetidine-3-carboxylate Hydrochloride >98.0%(T) | M2521 | 5g | $138 |
| Methyl azetidine-3-carboxylate hydrochloride | FM140349 | 5g | $150 |
| Methyl azetidine-3-carboxylate hydrochloride | FM140349 | 2g | $150 |
| Methyl azetidine-3-carboxylate hydrochloride | FM140349 | 1g | $150 |
| More product size | |||
| Melting point | 93.0 to 97.0 °C |
|---|---|
| Boiling point | 187-192℃ |
| Flash point | 69°(156°F) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| Water Solubility | Soluble in water |
| form | powder to crystal |
| color | White to Almost white |
| InChI | InChI=1S/C5H9NO2.ClH/c1-8-5(7)4-2-6-3-4;/h4,6H,2-3H2,1H3;1H |
| InChIKey | UOCWTLBPYROHEF-UHFFFAOYSA-N |
| SMILES | C(C1CNC1)(=O)OC.Cl |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 |
|||||||||
| NFPA 704 |
|
3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2521 | Methyl Azetidine-3-carboxylate Hydrochloride >98.0%(T) | 100202-39-9 | 1g | $48 | 2026-04-30 | Buy |
| TCI Chemical | M2521 | Methyl Azetidine-3-carboxylate Hydrochloride >98.0%(T) | 100202-39-9 | 5g | $138 | 2026-04-30 | Buy |
| Biosynth | FM140349 | Methyl azetidine-3-carboxylate hydrochloride | 100202-39-9 | 5g | $150 | 2026-06-04 | Buy |
| Biosynth | FM140349 | Methyl azetidine-3-carboxylate hydrochloride | 100202-39-9 | 2g | $150 | 2026-06-04 | Buy |
| Biosynth | FM140349 | Methyl azetidine-3-carboxylate hydrochloride | 100202-39-9 | 1g | $150 | 2026-06-04 | Buy |
3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
Methyl Azetidine-3-carboxylate Hydrochloride can be used to prepare inhibitors of of human glycogen phosphorylase to treat hyperglycemia, hyperinsulinemia, hyperlipidemia, insulin resistance or tissue ischemia.
Synthesis
53871-06-0
100202-39-9
The general procedure for the synthesis of methyl azetidine-3-carboxylate hydrochloride from methyl 1 -diphenylmethylazetidine-3-carboxylate was as follows (Preparative Example 85): methyl 1 -diphenylmethylazetidine-3-carboxylate (3.57 g) was dissolved in methanol (360 ml), and ethyl acetate solution of 4N hydrochloric acid (12.7 ml) was added, and the reaction system was maintained at 20 °C. Subsequently, palladium hydroxide (3.57 g) was added as a catalyst and the reaction was stirred at room temperature and under pressurized hydrogen atmosphere (0.4 MPa) for 11 hours. After completion of the reaction, the catalyst was removed by filtration and washed with methanol and water. The filtrate was concentrated to give the crude product of methyl azetidine-3-carboxylate hydrochloride, which presented as a light yellow oil. The reaction was assessed to be quantitative and 1.93 g of product was obtained, which can be used directly in subsequent reactions. The product was detected by ESI-MS, m/z: 116 [M + H]+.
IC 50
Non-cleavable Linker
References
[1] Patent: EP1889836, 2008, A1. Location in patent: Page/Page column 80
[2] Patent: US2008/214815, 2008, A1. Location in patent: Page/Page column 14-15
3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7240 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3004 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2163 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10817 | 58 |
View Lastest Price from 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-15 | 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
100202-39-9
|
$1.50 | 1g | 99.0% Min | 100 Tons | Shaanxi Didu New Materials Co. Ltd | |
 |
2025-05-23 | 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
100202-39-9
|
$50.00 | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2019-07-06 | 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
100202-39-9
|
$1.00 | 1kg | 98% | 200KG | Career Henan Chemical Co |
-
- 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
100202-39-9
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-
- 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
100202-39-9
- $50.00
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
100202-39-9
- $1.00
- 98%
- Career Henan Chemical Co
100202-39-9(3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE)Related Search:
1of4
