3-AMINOPYRAZINE-2-CARBONITRILE
- CAS No.
- 25911-65-3
- Chemical Name:
- 3-AMINOPYRAZINE-2-CARBONITRILE
- Synonyms
- BUTTPARK 29\04-92;2-aMino-3-cyanopyrazine;3-Amino-2-pyrazinecarbonitrile;Pyrazinecarbonitrile, 3-amino-;3-AMINOPYRAZINE-2-CARBONITRILE;2-Pyrazinecarbonitrile, 3-amino-;3-AMINOPYRAZINE-2-CARBONITRILE ISO 9001：2015 REACH
- CBNumber:
- CB2737212
- Molecular Formula:
- C5H4N4
- Molecular Weight:
- 120.11
- MDL Number:
- MFCD02091510
- MOL File:
- 25911-65-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Aminopyrazine-2-carbonitrile 98% | AS31611 | 1g | $29 |
| 3-Aminopyrazine-2-carbonitrile 98% | AS31611 | 5g | $138 |
| 3-Aminopyrazine-2-carbonitrile 98% | AS31611 | 25g | $584 |
| 3-Aminopyrazine-2-carbonitrile 98% | AS31611 | 100g | $1792 |
| 3-Aminopyrazine-2-carbonitrile | 073226 | 1.00g | $416 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
3-AMINOPYRAZINE-2-CARBONITRILE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS31611 | 3-Aminopyrazine-2-carbonitrile 98% | 25911-65-3 | 1g | $29 | 2026-06-04 | Buy |
| Activate Scientific | AS31611 | 3-Aminopyrazine-2-carbonitrile 98% | 25911-65-3 | 5g | $138 | 2026-06-04 | Buy |
| Activate Scientific | AS31611 | 3-Aminopyrazine-2-carbonitrile 98% | 25911-65-3 | 25g | $584 | 2026-06-04 | Buy |
| Activate Scientific | AS31611 | 3-Aminopyrazine-2-carbonitrile 98% | 25911-65-3 | 100g | $1792 | 2026-06-04 | Buy |
| Matrix Scientific | 073226 | 3-Aminopyrazine-2-carbonitrile | 25911-65-3 | 1.00g | $416 | 2026-05-18 | Buy |
3-AMINOPYRAZINE-2-CARBONITRILE Chemical Properties,Uses,Production
Uses
3-Aminopyrazine-2-carbonitrile is a useful synthesis reagent.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 26, p. 817, 1989 DOI: 10.1002/jhet.5570260357
Synthesis
32587-10-3
25911-65-3
Example 3 Synthesis of 3-aminopyrazine-2-carbonitrile (Intermediate 2): Intermediate 1 (3-aminopyrazine-2-carboxamide, 3.5 g, 25 mmol) was dissolved in DMF (40 mL) at room temperature, followed by slow dropwise addition of POCl3 (4.5 mL, 49 mmol). The reaction mixture was heated at 80 °C with stirring for 15 min, after which it was cooled to room temperature. The reaction mixture was slowly poured into ice water and the pH was adjusted to neutral with 10% NaOH solution. The precipitated solid was collected by filtration and redissolved in 5% HCl solution. The acidic solution was heated at 70 °C for 30 min, followed by filtration to separate the solid product. The target compound 3-aminopyrazine-2-carbonitrile was obtained as a brown solid (1.7 g, 56% yield) after sufficient washing with water. The product was characterized by 1H NMR (500 MHz, DMSO-d6): δ 8.28 (d, J=2.4 Hz, 1H), 7.90 (d, J=2.4 Hz, 1H), 7.32 (br s, 2H). Mass spectrum (ES+): m/z 121 ([M+H]+).
References
[1] Patent: US2007/259876, 2007, A1. Location in patent: Page/Page column 18
[2] Journal of the American Chemical Society, 1945, vol. 67, p. 1711
[3] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 12, p. 3238 - 3242
3-AMINOPYRAZINE-2-CARBONITRILE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 3-AMINOPYRAZINE-2-CARBONITRILE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 3-AMINOPYRAZINE-2-CARBONITRILE
25911-65-3
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2020-04-30 | 3-AMinopyrazine-2-carbonitrile
25911-65-3
|
1KG | 99.0%+ | 800 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-12-23 | 3-AMINOPYRAZINE-2-CARBONITRILE
25911-65-3
|
$1.00 | 1ASSAYS | 98% HPLC | 10t | Career Henan Chemical Co |
-
- 3-AMINOPYRAZINE-2-CARBONITRILE
25911-65-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-AMinopyrazine-2-carbonitrile
25911-65-3
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-AMINOPYRAZINE-2-CARBONITRILE
25911-65-3
- $1.00
- 98% HPLC
- Career Henan Chemical Co
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