5-CHLORO-2-METHYLINDOLE
- CAS No.
- 1075-35-0
- Chemical Name:
- 5-CHLORO-2-METHYLINDOLE
- Synonyms
- 5-Chloro-2-methyl-1H-indole;RARECHEM AH BS 0087;TIMTEC-BB SBB003903;2-METHYL-5-CHLOROINDOLE;5-CHLORO-2-METHYLINDOLE;5-Chloro-2-methylindole >5-Chloro-2-methylindole,95%;2-Methyl-5-chloro-1H-indole;5-CHLORO-2-METHYLINDOLE 97%;1H-Indole, 5-chloro-2-methyl-
- CBNumber:
- CB2755678
- Molecular Formula:
- C9H8ClN
- Molecular Weight:
- 165.62
- MDL Number:
- MFCD00005619
- MOL File:
- 1075-35-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Chloro-2-methylindole 97% | C52802 | 1g | $124 |
| 5-Chloro-2-methylindole 97% | C52802 | 10g | $744 |
| 5-Chloro-2-methylindole >98.0%(GC)(T) | C1761 | 1g | $57 |
| 5-Chloro-2-methylindole >98.0%(GC)(T) | C1761 | 5g | $167 |
| 5-Chloro-2-methylindole | FC02110 | 10g | $150 |
| More product size | |||
| Melting point | 112-118 °C |
|---|---|
| Boiling point | 140 °C / 0.1mmHg |
| Density | 1.1705 (rough estimate) |
| refractive index | 1.5390 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 16.66±0.30(Predicted) |
| color | White to Gray to Brown |
| InChIKey | WUVWAXJXPRYUME-UHFFFAOYSA-N |
| CAS DataBase Reference | 1075-35-0(CAS DataBase Reference) |
| FDA UNII | R53P7RYF43 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
5-CHLORO-2-METHYLINDOLE price More Price(72)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C52802 | 5-Chloro-2-methylindole 97% | 1075-35-0 | 1g | $124 | 2022-05-15 | Buy |
| Sigma-Aldrich | C52802 | 5-Chloro-2-methylindole 97% | 1075-35-0 | 10g | $744 | 2022-05-15 | Buy |
| TCI Chemical | C1761 | 5-Chloro-2-methylindole >98.0%(GC)(T) | 1075-35-0 | 1g | $57 | 2026-04-30 | Buy |
| TCI Chemical | C1761 | 5-Chloro-2-methylindole >98.0%(GC)(T) | 1075-35-0 | 5g | $167 | 2026-04-30 | Buy |
| Biosynth | FC02110 | 5-Chloro-2-methylindole | 1075-35-0 | 10g | $150 | 2026-06-04 | Buy |
5-CHLORO-2-METHYLINDOLE Chemical Properties,Uses,Production
Chemical Properties
light pink to beige-pale brown crystalline powder
Uses
2-Methyl-5-chloroindole has been shown to depress brainstem and telencephalon serotonin for 3 days after 24 hours of being administered intraventricularly.Dyes and metabolites.
Synthesis Reference(s)
Journal of the American Chemical Society, 96, p. 5495, 1974 DOI: 10.1021/ja00824a028
Synthesis
81327-26-6
1075-35-0
In a 100 mL stainless steel autoclave, 1.09 g (5.1 mmol) of 5-chloro-2-nitrophenylacetone and 72 mg (4 mol%) of cyclopentadienyl ferric dicarbonyl (dimer) were added as a catalyst and 40 g of toluene as a solvent, and the system was protected by nitrogen. After displacing the atmosphere in the reactor three times (10 kgf/cm2 nitrogen each time), carbon monoxide gas was injected to a pressure of 30 kgf/cm2. The reaction mixture was stirred at 120 °C for 5 h. The reaction was completed by cooling to room temperature. Upon completion of the reaction, it was cooled to room temperature and the complete conversion of 5-chloro-2-nitrophenylacetone was confirmed by liquid chromatography analysis. Subsequently, the reaction mixture was post-treated and purified by silica gel column chromatographic separation to afford 0.79 g (94.0% yield) of the target product 5-chloro-2-methylindole.
References
[1] Patent: US2007/83053, 2007, A1. Location in patent: Page/Page column 7
5-CHLORO-2-METHYLINDOLE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49859 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 |
View Lastest Price from 5-CHLORO-2-METHYLINDOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 5-CHLORO-2-METHYLINDOLE
1075-35-0
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-12-24 | 5-CHLORO-2-METHYLINDOLE
1075-35-0
|
$1.00 | 1KG | 99% | 1000KGS | Career Henan Chemical Co |
-
- 5-CHLORO-2-METHYLINDOLE
1075-35-0
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-CHLORO-2-METHYLINDOLE
1075-35-0
- $1.00
- 99%
- Career Henan Chemical Co
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