4,4-dimethylpiperidinium chloride
- CAS No.
- 38646-68-3
- Chemical Name:
- 4,4-dimethylpiperidinium chloride
- Synonyms
- 4,4-Dimethylpiperidine HCl;4,4-dimethylpiperidine hy...;4,4-Dimethyl-piperidine x HCl;4,4-dimethylpiperidinium chloride;4,4-Dimethylpiperidinium hydrochloride;4,4-dimethyl-2,3,5,6-tetrahydropyridin-1-ylium chloride
- CBNumber:
- CB2940254
- Molecular Formula:
- C7H16ClN
- Molecular Weight:
- 149.66164
- MDL Number:
- MFCD00035295
- MOL File:
- 38646-68-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS06,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H330-H314-H226 |
| Precautionary statements | P501-P260-P240-P210-P233-P243-P241-P242-P271-P264-P280-P284-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P233-P403+P235-P405 |
| HazardClass | IRRITANT |
4,4-dimethylpiperidinium chloride price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 61353 | 4,4-DIMETHYLPIPERIDINE HCL 97% | 38646-68-3 | 5G | $53 | 2026-04-30 | Buy |
| AstaTech | 61353 | 4,4-DIMETHYLPIPERIDINE HCL 97% | 38646-68-3 | 25G | $243 | 2026-04-30 | Buy |
| AstaTech | 61353 | 4,4-DIMETHYLPIPERIDINE HCL 97% | 38646-68-3 | 100G | $977 | 2026-04-30 | Buy |
| Matrix Scientific | 027103 | 4,4-Dimethylpiperidine hydrochloride | 38646-68-3 | 5.00g | $55 | 2026-05-18 | Buy |
| Matrix Scientific | 027103 | 4,4-Dimethylpiperidine hydrochloride | 38646-68-3 | 10.00g | $107 | 2026-05-18 | Buy |
4,4-dimethylpiperidinium chloride Chemical Properties, Uses, Production
Synthesis
1123-40-6
38646-68-3
The general procedure for the synthesis of 4,4-dimethylpiperidine hydrochloride from 3,3-dimethylglutamine is as follows: 1. Preparation of 4,4-dimethylpiperidine: Under argon protection, solid lithium aluminum hydride (2.5 g, 64 mmol) was added to a 500 mL round-bottom flask, and 40 mL of anhydrous tetrahydrofuran was added slowly. The suspension was cooled to 0 °C and then a solution of 3,3-dimethylglutarimide (3.0 g, 21 mmol) dissolved in 20 mL of anhydrous tetrahydrofuran was slowly added. Gas was observed to escape during the reaction. After the addition was completed, the ice bath was removed and the reaction mixture was allowed to gradually warm up to room temperature. A condenser was installed and the flask was placed in an oil bath and heated to reflux for 3 hours. 2. Post-treatment: The reaction solution is cooled to room temperature and the flask is subsequently placed in a cold water bath. 2.5mL of water, 2.5mL of 15% aqueous sodium hydroxide solution and 7.5mL of water were added slowly and dropwise to produce a thick suspension. Add 150mL of dry ether, stir and filter to remove solids. Separate the organic layer, dry with anhydrous sodium sulfate and filter. 3. Salt formation: The organic solution was cooled in an ice bath and anhydrous hydrogen chloride gas was passed for 30 seconds to produce a thick white precipitate. The solid was collected by filtration to give 4,4-dimethylpiperidine hydrochloride (2.68 g, 85% yield). Mass spectrometry analysis (APCI+): m/z 114.1.
References
[1] Chemical and Pharmaceutical Bulletin, 1993, vol. 41, # 11, p. 1971 - 1986
[2] Patent: WO2008/84300, 2008, A1. Location in patent: Page/Page column 57
4,4-dimethylpiperidinium chloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
4,4-dimethylpiperidinium chloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6959 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Cuisen Pharmaceutical Technology Co., Ltd. | 13472757003 | yongnan.wang@cendrix.cn | China | 974 | 65 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Aloespharm Co., Ltd. | 021-20960837 | market@aloespharm.com | China | 1299 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Porse Fine Chemical Co.,LTD | 20-66003216 18666003216 | info@porsefinechemical.com | China | 1963 | 62 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
38646-68-3 (4,4-dimethylpiperidinium chloride) Related Search:
1of4
