4-Benzyl-2-morpholinecarboxylic acid hydrochloride
- CAS No.
- 135072-15-0
- Chemical Name:
- 4-Benzyl-2-morpholinecarboxylic acid hydrochloride
- Synonyms
- 4-Benzyl-2-morpholinecarboxylicacidHCl;4-Benzyl-2-carboxymorpholine hydrochloride;BENZYL(N-)-MORPHOLINE-2-CARBOXYLIC ACID HCL;4-Benzyl-2-morpholinecarboxylic acid hydrochloride;4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID HYDROCHLORIDE;4-Benzylmorpholine-2-carboxylicacidhydrochloride,97%;4-Benzyl-2-morpholinecarboxylic acid hydrochloride, 90+%;4-Benzyl-2-carboxymorpholine hydrochloride, 10 mM in DMSO;2-Morpholinecarboxylic acid, 4-(phenylmethyl)-, hydrochloride;4-(phenylmethyl)-2-Morpholinecarboxylic acid hydrochloride (1:1)
- CBNumber:
- CB3101320
- Molecular Formula:
- C12H16ClNO3
- Molecular Weight:
- 257.71
- MDL Number:
- MFCD02682031
- MOL File:
- 135072-15-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
4-Benzyl-2-morpholinecarboxylic acid hydrochloride price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR23182 | 4-Benzylmorpholine-2-carboxylic acid hydrochloride ≥95% | 135072-15-0 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR23182 | 4-Benzylmorpholine-2-carboxylic acid hydrochloride ≥95% | 135072-15-0 | 1g | $28 | 2026-06-04 | Buy |
| Apolloscientific | OR23182 | 4-Benzylmorpholine-2-carboxylic acid hydrochloride ≥95% | 135072-15-0 | 5g | $39 | 2026-06-04 | Buy |
| Matrix Scientific | 072259 | 4-Benzyl-2-morpholinecarboxylic acid hydrochloride | 135072-15-0 | 1.00g | $185 | 2026-05-18 | Buy |
| Matrix Scientific | 072259 | 4-Benzyl-2-morpholinecarboxylic acid hydrochloride | 135072-15-0 | 5.00g | $500 | 2026-05-18 | Buy |
4-Benzyl-2-morpholinecarboxylic acid hydrochloride Chemical Properties, Uses, Production
Synthesis
147767-51-9
135072-15-0
4-Benzylmorpholine-2-carbonitrile (64.1 g, 316.9 mmol) was used as the raw material, which was dissolved in 6 N aqueous hydrochloric acid (600 mL) and the reaction was heated to reflux for 2.5 hours. After the reaction was completed, the reaction solution was cooled to -10 °C. The precipitated solid product was collected by filtration and washed with acetone (300 mL) pre-cooled to -10 °C. The resulting solid was dried in an oven at 60 °C to afford 4-benzyl-2-morpholine carboxylic acid hydrochloride (78.7 g, 305.4 mmol, 96% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 2.18 (broad peak, -COOH), 7.67-7.65 (multiple peaks, 2H), 7.53-7.40 (multiple peaks, 3H), 4.61 (double peak, J = 10.8 Hz, 1H), 4.39 (multiple peaks, 2H), 4.05-4.94 (multiple peaks, 2H) , 3.43 (double peak, J = 12.0 Hz, 1H), 3.20-3.07 (multiple peaks, 3H).
References
[1] Patent: WO2012/128582, 2012, A2. Location in patent: Page/Page column 28
[2] Patent: WO2005/47272, 2005, A1. Location in patent: Page/Page column 48-49
[3] Organic Process Research and Development, 2009, vol. 13, # 2, p. 209 - 224
[4] Patent: WO2010/59658, 2010, A1. Location in patent: Page/Page column 225
4-Benzyl-2-morpholinecarboxylic acid hydrochloride Preparation Products And Raw materials
4-Benzyl-2-morpholinecarboxylic acid hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| ForeChem (Nantong) Technology Co.,Ltd. | 513-85982855 18921614129 | sales@xianxingpharm.com | China | 2712 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
View Latest Price from 4-Benzyl-2-morpholinecarboxylic acid hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-10 | 4-Benzyl-2-carboxymorpholine hydrochloride
135072-15-0
|
$32.00-72.00 | 99.97% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-01-03 | 4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE
135072-15-0
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 4-Benzyl-2-carboxymorpholine hydrochloride
135072-15-0
- $32.00-72.00
- 99.97%
- TargetMol Chemicals Inc.
-
- 4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE
135072-15-0
- $1.00
- 99%
- Career Henan Chemical Co
