ChemicalBook >> CAS DataBase List >>O-Desmorpholinopropyl Gefitinib
O-Desmorpholinopropyl Gefitinib
- CAS No.
- 184475-71-6
- Chemical Name:
- O-Desmorpholinopropyl Gefitinib
- Synonyms
- Gefitinib iMpurity C;4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol;4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol;4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol;FAAH-IN-2;Des-Gefitinib;N-(3-Chloro-4-f;FAAH inhibitor 2;Gefitinib Intermediate 1;FAAH-IN-2, 10 mM in DMSO
- CBNumber:
- CB31176644
- Molecular Formula:
- C15H11ClFN3O2
- Molecular Weight:
- 319.72
- MDL Number:
- MFCD09908046
- MOL File:
- 184475-71-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 00:55:56
| Melting point | >260°C (dec.) |
|---|---|
| Boiling point | 478.8±45.0 °C(Predicted) |
| Density | 1.489±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Very Slightly, Heated) |
| form | Solid |
| pka | 8.18±0.40(Predicted) |
| color | Pale Beige to Beige |
| InChI | InChI=1S/C15H11ClFN3O2/c1-22-14-6-12-9(5-13(14)21)15(19-7-18-12)20-8-2-3-11(17)10(16)4-8/h2-7,21H,1H3,(H,18,19,20) |
| InChIKey | JLVTVCRXFMLUIF-UHFFFAOYSA-N |
| SMILES | N1=C2C(C=C(O)C(OC)=C2)=C(NC2=CC=C(F)C(Cl)=C2)N=C1 |
| FDA UNII | V26QDI5C8D |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933.59.8000 |
O-Desmorpholinopropyl Gefitinib price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C3647 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol | 184475-71-6 | 1G | $46 | 2026-04-30 | Buy |
| TCI Chemical | C3647 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol | 184475-71-6 | 5G | $157 | 2026-04-30 | Buy |
| Usbiological | 008737 | O-Desmorpholinopropyl Gefitinib | 184475-71-6 | 100mg | $418 | 2026-06-03 | Buy |
| Biosynth | FD21367 | O-Desmorpholinopropyl gefitinib | 184475-71-6 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | FD21367 | O-Desmorpholinopropyl gefitinib | 184475-71-6 | 50g | $900 | 2026-06-04 | Buy |
O-Desmorpholinopropyl Gefitinib Chemical Properties, Uses, Production
Description
O-Desmorpholinopropyl Gefitinib is a metabolite of Gefitinib, a potent inhibitor of tyrosine phosporylation in EGFR. The chemical structure of O-Desmorpholinopropyl Gefitinib consists of a quinazoline-6-ol core with a phenylamino group attached to a chloro-fluoro-phenyl ring, enabling it to interact with multiple biological targets. It is involved in inhibiting enzymes such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).
Chemical Properties
Tan Solid
Uses
A metabolite of Gefitinib.
Definition
ChEBI: O-Desmorpholinopropyl Gefitinib is a member of quinazolines.
Synthesis of O-Desmorpholinopropyl Gefitinib from 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate
O-Desmorpholinopropyl Gefitinib Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 240)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6740 | 52 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 |
View Latest Price from O-Desmorpholinopropyl Gefitinib manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
184475-71-6
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | O-Desmorpholinopropyl Gefitinib
184475-71-6
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2024-11-26 | 4-(3-chloro-4-fluorophenylami-no)-7-methoxyquinazolin-6-ol
184475-71-6
|
1kg | 99%(HPLC) | 5000kg | Nanjing Fred Technology Co., Ltd |
-
- 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
184475-71-6
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- O-Desmorpholinopropyl Gefitinib
184475-71-6
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4-(3-chloro-4-fluorophenylami-no)-7-methoxyquinazolin-6-ol
184475-71-6
- 99%(HPLC)
- Nanjing Fred Technology Co., Ltd
184475-71-6 (O-Desmorpholinopropyl Gefitinib) Related Search:
Gefitinib Impurity 8
Gefitinib Chloro Impurity
Gefitinib Impurity 11
Gefitinib-d6
6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
1of4
FAAH-IN-2
4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline
4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol
O-Desmorpholinopropyl Gefitinib
Gefitinib interMediate VII
Gefitinib Intermediate 1
4-(3-Chloro-4-fluoroanilino)-6-hydroxy-7-methoxyquinazoline
N-(3-Chloro-4-f
FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib)
6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)aMino]-7-Methoxy-
Gefitinib Impurity 12 (O-Desmorpholinopropyl Gefitinib)
FAAH inhibitor 2
Gefitinib O-Desmorpholinopropyl Impurity
4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol
Des-Gefitinib
4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-ol (O-Desmorpholinopropylgefitinib)
FAAH-IN-2 (Gefitinib Impurity)
4- (3-Chloro-4-fluorophenylamino) -7-methoxyquinoline-6-alcohol
FAAH-IN-2, 10 mM in DMSO
4-(3-Chloro-4-fluorobenzamino)-7-methoxyquinazolin-6-ol
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Gefitinib iMpurity C
184475-71-6
C15H11ClFN3O2
Gefitinib
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
