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2-Bromo-5-formyl-3-methylpyridine

2-Bromo-5-formyl-3-methylpyridine Structure
2-Bromo-5-formyl-3-methylpyridine structure
CAS No.
885167-81-7
Chemical Name:
2-Bromo-5-formyl-3-methylpyridine
Synonyms
KML-12;CML-014;6-bromo-5-methylnicotinaldehyde;2-Bromo-5-formyl-3-methylpyridine;6-BroMo-5-Methyl-pyridine-3-carbaldehyde;6-Bromo-5-methyl-3-pyridinecarboxaldehyde;3-Pyridinecarboxaldehyde, 6-bromo-5-methyl-
CBNumber:
CB31512482
Molecular Formula:
C7H6BrNO
Molecular Weight:
200.03
MDL Number:
MFCD08277302
MOL File:
885167-81-7.mol
MSDS File:
SDS
Last updated:2026-05-28 01:02:18
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2-Bromo-5-formyl-3-methylpyridine Properties

Boiling point 300.2±42.0 °C(Predicted)
Density 1.577±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -0.72±0.20(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H303-H320
Precautionary statements  P312-P264-P305+P351+P338-P337+P313

2-Bromo-5-formyl-3-methylpyridine price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS114418 6-Bromo-5-methylnicotinaldehyde 95% 885167-81-7 1g $171 2026-06-04 Buy
Activate Scientific AS114418 6-Bromo-5-methylnicotinaldehyde 95% 885167-81-7 5g $638 2026-06-04 Buy
Matrix Scientific 174579 6-Bromo-5-methylnicotinaldehyde 885167-81-7 250.00mg $32 2026-05-18 Buy
Matrix Scientific 174579 6-Bromo-5-methylnicotinaldehyde 885167-81-7 1.00g $111 2026-05-18 Buy
Matrix Scientific 174579 6-Bromo-5-methylnicotinaldehyde 885167-81-7 5.00g $438 2026-05-18 Buy
Product number Packaging Price Buy
AS114418 1g $171 Buy
AS114418 5g $638 Buy
174579 250.00mg $32 Buy
174579 1.00g $111 Buy
174579 5.00g $438 Buy

2-Bromo-5-formyl-3-methylpyridine Chemical Properties, Uses, Production

Synthesis

4-Formylmorpholine

4394-85-8

2,5-Dibromo-3-methylpyridine

3430-18-0

2-Bromo-5-formyl-3-methylpyridine

885167-81-7

The general procedure for the synthesis of 2-bromo-3-methyl-5-formylpyridine from N-formylmorpholine and 2,5-dibromo-3-methylpyridine is as follows: Method 4: Preparation of 6-bromo-5-methylnicotinaldehyde 1. A solution of 2,5-dibromo-3-methylpyridine (5.1 g, 20.30 mmol) in tetrahydrofuran (25 ml) was slowly added dropwise to a solution of 2M isopropylmagnesium chloride (10.7 ml, 21.3 mmol) in tetrahydrofuran which had been pre-cooled to 0 °C at 0 °C. 2. The reaction mixture was stirred at 0°C for 2 hours, followed by continued stirring at room temperature for 1 hour. 3. a solution of tetrahydrofuran (25 ml) of 4-formylmorpholine (2.1 ml, 20.3 mmol) was slowly added dropwise to the reaction mixture, and after completion of the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. 4. The reaction mixture was poured into water and the aqueous phase was extracted with ethyl acetate. The organic phases were combined, washed with saturated brine, dried over anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. 5. The residue was purified by fast column chromatography to afford the target product 2-bromo-3-methyl-5-formylpyridine (3.0 g, 74% yield) using isohexane solution of 10% ethyl acetate as eluent. NMR spectrum (DMSO-d6): δ 2.44 (s, 3H), 8.19 (s, 1H), 8.73 (s, 1H), 10.09 (s, 1H).

References

[1] Patent: US2008/119451, 2008, A1. Location in patent: Page/Page column 35
[2] Patent: WO2007/71956, 2007, A1. Location in patent: Page/Page column description
[3] Patent: US2012/184520, 2012, A1. Location in patent: Page/Page column 24

2-Bromo-5-formyl-3-methylpyridine Preparation Products And Raw materials

Raw materials

4-Formylmorpholine 2,5-Dibromo-3-methylpyridine Isopropylmagnesium chloride Tetrahydrofuran

Preparation Products

2-Bromo-5-formyl-3-methylpyridine Suppliers

Global Suppliers ( 71)
Supplier Tel Email Country ProdList Advantage
Zhuhai Aobokai Biomedical Technology Co., Ltd. 400-0628126 sales-team@aobchem.com.cn China 9998 58
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Anichem Inc. 0512-69369885 sales@anichem.com.cn China 493 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 18151128828 hc-sales@foxmail.com China 2635 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
NovoChemy Ltd. 86-(0)21-31261262 373522135 sales@novochemy.com China 6491 58
Supplier Advantage
Zhuhai Aobokai Biomedical Technology Co., Ltd. 58
Capot Chemical Co., Ltd 66
Shanghai Ennopharm Co., Ltd. 65
Shanghai Raise Chemical Technology Co.,Ltd 55
Anichem Inc. 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 55
Bide Pharmatech Ltd. 60
Shanghai HuanChuan Industry Co.,Ltd. 50
Cool Pharm, Ltd 58
NovoChemy Ltd. 58

View Latest Price from 2-Bromo-5-formyl-3-methylpyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-5-formyl-3-methylpyridine pictures 2020-01-14 2-Bromo-5-formyl-3-methylpyridine
885167-81-7
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

2-Bromo-5-formyl-3-methylpyridine Spectrum

2-Bromo-5-formyl-3-methylpyridine(885167-81-7)1HNMR

885167-81-7 (2-Bromo-5-formyl-3-methylpyridine) Related Search:

2-Bromo-3-methylpyridine-5-carboxylic acid 2-Bromopyridine-5-carbaldehyde 2-Bromo-5-formyl-3-methylpyridine 2-Bromo-5-cyano-3-picoline 2,6-Dibromopyridine-3-carboxaldehyde
2-Bromo-3-formylpyridine

1of2

2-Bromo-5-formyl-3-methylpyridine 6-bromo-5-methylnicotinaldehyde 6-BroMo-5-Methyl-pyridine-3-carbaldehyde CML-014 3-Pyridinecarboxaldehyde, 6-bromo-5-methyl- 6-Bromo-5-methyl-3-pyridinecarboxaldehyde KML-12 885167-81-7 Boronic Acid Heterocyclic Compounds