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2-Bromopyridine-5-carbaldehyde

2-Bromopyridine-5-carbaldehyde structure

CAS No.: 149806-06-4

Chemical Name:: 2-Bromopyridine-5-carbaldehyde

Synonyms: 6-BROMONICOTINALDEHYDE;2-BROMO-5-FORMYLPYRIDINE;6-BROMO-PYRIDINE-3-CARBALDEHYDE;6-Bromo-3-pyridinecarbaldehyde;6-BROMO-3-PYRIDINECARBOXALDEHYDE;6-BROMOPYRIDINE-3-CARBOXALDEHYDE;2-Bromo-5-aldopyridine;Abemaciclib Impurity 37;6-Bromo-3-pyridinecarboxaL;2-BROMO-5-FORMYLPYRIDINE97+%

CBNumber:: CB5396137

Molecular Formula:: C6H4BrNO

Molecular Weight:: 186.01

MDL Number:: MFCD04115419

MOL File:: 149806-06-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:22:16

Product description	Number	Pack Size	Price
6-Bromo-3-pyridinecarboxaldehyde 95%	596280	1g	$31.7
6-Bromo-3-pyridinecarboxaldehyde 95%	596280	5g	$98.4
6-Bromo-3-pyridinecarboxaldehyde >98.0%(GC)	B3491	1g	$17
6-Bromo-3-pyridinecarboxaldehyde >98.0%(GC)	B3491	5g	$51
6-Bromopyridine-3-carboxaldehyde	B2866-70A	1g	$347
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2-Bromopyridine-5-carbaldehyde Properties

Melting point	104-110 °C(lit.)
Boiling point	284°
Density	1.683
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in dichloromethane, ether, ethyl acetate and methanol.
form	Solid
pka	-1.01±0.10(Predicted)
color	Pale yellow
Sensitive	Air Sensitive
InChI	InChI=1S/C6H4BrNO/c7-6-2-1-5(4-9)3-8-6/h1-4H
InChIKey	PVUKGNBRJFTFNJ-UHFFFAOYSA-N
SMILES	C1=NC(Br)=CC=C1C=O
CAS DataBase Reference	149806-06-4(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HazardClass

IRRITANT

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		1

2-Bromopyridine-5-carbaldehyde price More Price(122)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	596280	6-Bromo-3-pyridinecarboxaldehyde 95%	149806-06-4	1g	$31.7	2026-04-30	Buy
Sigma-Aldrich	596280	6-Bromo-3-pyridinecarboxaldehyde 95%	149806-06-4	5g	$98.4	2026-04-30	Buy
TCI Chemical	B3491	6-Bromo-3-pyridinecarboxaldehyde >98.0%(GC)	149806-06-4	1g	$17	2026-04-30	Buy
TCI Chemical	B3491	6-Bromo-3-pyridinecarboxaldehyde >98.0%(GC)	149806-06-4	5g	$51	2026-04-30	Buy
Usbiological	B2866-70A	6-Bromopyridine-3-carboxaldehyde	149806-06-4	1g	$347	2026-06-03	Buy

Product number	Packaging	Price	Buy
596280	1g	$31.7	Buy
596280	5g	$98.4	Buy
B3491	1g	$17	Buy
B3491	5g	$51	Buy
B2866-70A	1g	$347	Buy

2-Bromopyridine-5-carbaldehyde Chemical Properties,Uses,Production

Chemical Properties

Light yellow Cryst

Uses

2-Bromopyridine-5-carbaldehyde can be a useful synthetic intermediate

Uses

A useful synthetic intermediate. 6-Bromonicotinaldehyde is used in wittig reaction. Hydrodehalogenation of 6-bromonicotinaldehyde to produce alcohol.

Synthesis

154321-32-1

149806-06-4

General procedure for the synthesis of 2-bromo-5-formylpyridine (Intermediate 1b) from 2-bromo-5-(dibromomethyl)pyridine (Intermediate Ia, 3.650 g, 11.07 mmol): a mixture of Intermediate Ia with calcium carbonate (2.437 g, 24.35 mmol) in water (80 ml) was stirred and reacted for 16 hours at 105 °C. After completion of the reaction, the mixture was cooled to room temperature, diluted with water and extracted twice with ethyl acetate (EtOAc). The organic phases were combined, washed sequentially with water and saturated sodium chloride (NaCl) solution, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give Intermediate 1b (1.890 g, 92% yield). The product was characterized by 1H NMR (500 MHz, CDCl3): δ 10.05 (s, 1H), 8.78 (d, J = 2.2 Hz, 1H), 7.98 (dd, J = 8.2,2.4 Hz, 1H), 7.65 (d, J = 8.2 Hz, 1H).

References

[1] Patent: WO2016/124747, 2016, A1. Location in patent: Page/Page column 58; 59
[2] Patent: US2018/202388, 2018, A1
[3] Tetrahedron Letters, 2005, vol. 46, # 36, p. 6033 - 6036
[4] Synthesis, 1994, # 1, p. 87 - 92

2-Bromopyridine-5-carbaldehyde synthesis

Synthesis of 2-Bromopyridine-5-carbaldehyde from Pyridine, 2-bromo-5-(dibromomethyl)-

2-Bromopyridine-5-carbaldehyde Preparation Products And Raw materials

Raw materials

2,5-Dibromopyridine Pyridine, 2-bromo-5-(dibromomethyl)- 2-Chloropyridine-5-carbaldehyde N,N-Dimethylformamide 2-Bromo-5-iodopyridine

Pyridine, 2-bromo-5-(bromomethyl)- (9CI) Formaldehyde Butylmagnesium chloride Calcium carbonate

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Preparation Products

6-Bromonicotinic acid 6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXALDEHYDE Pyridine, 2-bromo-5-(dimethoxymethyl)- 6-Thien-2-ylnicotinaldehyde 6-(2,4-Difluorophenyl)-3-pyridinecarbaldehyde

(R)-Methyl-(5,6,7,8-tetrahydro-quinolin-8-yl)-amine 6-(3-Trifluoromethylphenyl)pyridine-3-carboxaldehyde tert-Butyl 4-((6-bromopyridin-3-yl)methyl)piperazine-1-carboxylate 6-[4-(TrifluoroMethoxy)phenyl]-3-pyridinecarbaldehyde 6-Butylnicotinaldehyde

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2-Bromopyridine-5-carbaldehyde Suppliers

Global( 516)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Highfine Biotech Co.,Ltd.	+86-0512-68071238 +86-13771819922	june@highfine.com	China	489	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5228	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60

Supplier	Advantage
Suzhou Highfine Biotech Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Moxin Chemicals	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60

View Lastest Price from 2-Bromopyridine-5-carbaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-28	2-Bromopyridine-5-Carbaldehyde 149806-06-4	$2.00-5.00	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2026-03-20	6-Bromonicotinaldehyde 149806-06-4	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-12-16	Abemaciclib Impurity 37 149806-06-4		10mg	95%+	10000	Moxin Chemicals

2-Bromopyridine-5-Carbaldehyde
149806-06-4
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

6-Bromonicotinaldehyde
149806-06-4
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

Abemaciclib Impurity 37
149806-06-4
95%+
Moxin Chemicals

2-Bromopyridine-5-carbaldehyde Spectrum

2-Bromopyridine-5-carbaldehyde(149806-06-4)¹HNMR 2-Bromopyridine-5-carbaldehyde(149806-06-4)FT-IR

149806-06-4(2-Bromopyridine-5-carbaldehyde)Related Search:

3-Aminopyridine 4-Methylpyridine Chromium picolinate Sulfasalazine 1-Hexadecylpyridinium bromide

2-Carboxybenzaldehyde 2-Bromopyridine 6-Bromonicotinic acid 5,6-DIBROMOPYRIDINE-3-CARBOXYLIC ACID t-butyl 6-bromo-3-pyridinecarboxylate

N-methyl 2-bromo-5-pyridinecarboxamide 2-Bromo-5-formyl-3-methylpyridine 5-Acetyl-2-bromopyridine Methyl 6-bromonicotinate 6-BROMONICOTINAMIDE

5-Bromo-3-pyridinecarboxaldehyde 2-Bromopyridine-4-carbaldehyde ,97%,2-BROMOPYRIDINE-4-CARBALDEHYDE 1-(6-BROMO-PYRIDIN-3-YL)-2,2,2-TRIFLUORO-ETHANONE

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2-BROMOPYRIDINE-5-CARBALDEHYDE 2-BROMOPYRIDINE-5-CARBOXALDEHYDE 2-BROMO-5-PYRIDINECARBOXALDEHYDE 6-BROMOPYRIDINE-3-CARBOXALDEHYDE 6-BROMO-3-PYRIDINECARBOXALDEHYDE 2-BROMO-5-FORMYLPYRIDINE97+% 6-Bromo-3-pyridinecarboxaldehyde,95% 6-Bromopyridine-3-carboxaldehyde, 6-Bromo-3-formylpyridine 2-Bromo-5-formylpyridine 6-Bromonicotinaldehyde 2-BroMopridine-5-carbaldehyde 3-Pyridinecarboxaldehyde,6-broMo- 6-BroMo-3-pyridinecarboxaldehyde, 98%, 98% 6-Bromo-3-pyridinecarboxaldehyde 95% 6-Bromopyridine-3-carboxaldehyde, 2-Bromo-5-formylpyridine 6-Bromo-3-pyridinecarboxaldehyde > 6-Bromopyridine-3-carboxaldehyde, 98%, for synthesis 2-Bromo-5-aldopyridine 6-Bromo-3-pyridinecarboxaL 2-Bromopyridine-5-carbaldehyde ISO 9001：2015 REACH TIANFU CHEM-- 2-Bromopyridine-5-carbaldehyde 2- bromo -5- aldehyde pyridine 2-BROMO-5-PYRIDINECARBOXALDEHYDEChemicalbook Abemaciclib Impurity 37 2-BROMO-5-FORMYLPYRIDINE 6-BROMO-PYRIDINE-3-CARBALDEHYDE 6-Bromo-3-pyridinecarbaldehyde 6-BROMONICOTINALDEHYDE 149806-06-4 34160-40-3 Heterocyclic Building Blocks Halogenated Heterocycles Pyridines Building Blocks Heterocycle-Pyridine series C1 to C6 C5 to C6 C6 to C7 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Organic Building Blocks Bases & Related Reagents Nucleotides C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridine Series pharmacetical Aldehydes Pyridines Aldehyde Building Blocks Nucleotides and Nucleosides Carbonyl Compounds Heterocycles Pyridine