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2-Bromopyridine-5-carbaldehyde

2-Bromopyridine-5-carbaldehyde structure

CAS No.: 149806-06-4

Chemical Name:: 2-Bromopyridine-5-carbaldehyde

Synonyms: 6-BROMONICOTINALDEHYDE;2-BROMO-5-FORMYLPYRIDINE;6-BROMO-PYRIDINE-3-CARBALDEHYDE;6-Bromo-3-pyridinecarbaldehyde;6-BROMO-3-PYRIDINECARBOXALDEHYDE;6-BROMOPYRIDINE-3-CARBOXALDEHYDE;2-Bromo-5-aldopyridine;Abemaciclib Impurity 37;6-Bromo-3-pyridinecarboxaL;2-BROMO-5-FORMYLPYRIDINE97+%

CBNumber:: CB5396137

Molecular Formula:: C6H4BrNO

Molecular Weight:: 186.01

MDL Number:: MFCD04115419

MOL File:: 149806-06-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-29 08:43:58

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2-Bromopyridine-5-carbaldehyde Properties

Melting point	104-110 °C(lit.)
Boiling point	284°
Density	1.683
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in dichloromethane, ether, ethyl acetate and methanol.
form	Solid
pka	-1.01±0.10(Predicted)
color	Pale yellow
Sensitive	Air Sensitive
InChI	InChI=1S/C6H4BrNO/c7-6-2-1-5(4-9)3-8-6/h1-4H
InChIKey	PVUKGNBRJFTFNJ-UHFFFAOYSA-N
SMILES	C1=NC(Br)=CC=C1C=O
CAS DataBase Reference	149806-06-4(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HazardClass

IRRITANT

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		1

2-Bromopyridine-5-carbaldehyde price More Price(108)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	596280	6-Bromo-3-pyridinecarboxaldehyde 95%	149806-06-4	1g	$31.7	2026-04-30	Buy
Sigma-Aldrich	596280	6-Bromo-3-pyridinecarboxaldehyde 95%	149806-06-4	5g	$98.4	2026-04-30	Buy
TCI Chemical	B3491	6-Bromo-3-pyridinecarboxaldehyde >98.0%(GC)	149806-06-4	1g	$17	2026-04-30	Buy
TCI Chemical	B3491	6-Bromo-3-pyridinecarboxaldehyde >98.0%(GC)	149806-06-4	5g	$51	2026-04-30	Buy
Usbiological	B2866-70A	6-Bromopyridine-3-carboxaldehyde	149806-06-4	1g	$347	2026-06-03	Buy

Product number	Packaging	Price	Buy
596280	1g	$31.7	Buy
596280	5g	$98.4	Buy
B3491	1g	$17	Buy
B3491	5g	$51	Buy
B2866-70A	1g	$347	Buy

2-Bromopyridine-5-carbaldehyde Chemical Properties, Uses, Production

Chemical Properties

Light yellow Cryst

Uses

2-Bromopyridine-5-carbaldehyde can be a useful synthetic intermediate

Uses

A useful synthetic intermediate. 6-Bromonicotinaldehyde is used in wittig reaction. Hydrodehalogenation of 6-bromonicotinaldehyde to produce alcohol.

Synthesis

154321-32-1

149806-06-4

General procedure for the synthesis of 2-bromo-5-formylpyridine (Intermediate 1b) from 2-bromo-5-(dibromomethyl)pyridine (Intermediate Ia, 3.650 g, 11.07 mmol): a mixture of Intermediate Ia with calcium carbonate (2.437 g, 24.35 mmol) in water (80 ml) was stirred and reacted for 16 hours at 105 °C. After completion of the reaction, the mixture was cooled to room temperature, diluted with water and extracted twice with ethyl acetate (EtOAc). The organic phases were combined, washed sequentially with water and saturated sodium chloride (NaCl) solution, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give Intermediate 1b (1.890 g, 92% yield). The product was characterized by 1H NMR (500 MHz, CDCl3): δ 10.05 (s, 1H), 8.78 (d, J = 2.2 Hz, 1H), 7.98 (dd, J = 8.2,2.4 Hz, 1H), 7.65 (d, J = 8.2 Hz, 1H).

References

[1] Patent: WO2016/124747, 2016, A1. Location in patent: Page/Page column 58; 59
[2] Patent: US2018/202388, 2018, A1
[3] Tetrahedron Letters, 2005, vol. 46, # 36, p. 6033 - 6036
[4] Synthesis, 1994, # 1, p. 87 - 92

2-Bromopyridine-5-carbaldehyde synthesis

Synthesis of 2-Bromopyridine-5-carbaldehyde from Pyridine, 2-bromo-5-(dibromomethyl)-

2-Bromopyridine-5-carbaldehyde Preparation Products And Raw materials

Raw materials

2,5-Dibromopyridine Pyridine, 2-bromo-5-(dibromomethyl)- 2-Chloropyridine-5-carbaldehyde N,N-Dimethylformamide 2-Bromo-5-iodopyridine

Pyridine, 2-bromo-5-(bromomethyl)- (9CI) Formaldehyde Butylmagnesium chloride Calcium carbonate

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Preparation Products

6-Bromonicotinic acid 6-(Trifluoromethyl)pyridine-3-carboxaldehyde Pyridine, 2-bromo-5-(dimethoxymethyl)- 6-Thien-2-ylnicotinaldehyde 6-(2,4-Difluorophenyl)-3-pyridinecarbaldehyde

(R)-Methyl-(5,6,7,8-tetrahydro-quinolin-8-yl)-amine 6-(3-Trifluoromethylphenyl)pyridine-3-carboxaldehyde tert-Butyl 4-((6-bromopyridin-3-yl)methyl)piperazine-1-carboxylate 6-[4-(TrifluoroMethoxy)phenyl]-3-pyridinecarbaldehyde 6-Butylnicotinaldehyde

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2-Bromopyridine-5-carbaldehyde Suppliers

Global Suppliers ( 529)

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing Habo Medical Technology Co., Ltd.	13376080562 13376090521	sales@habotech.com	China	726	60
Suzhou Highfine Biotech Co., Ltd	0512-69209928 18796809688	zhouyingxiang@highfine.com	China	472	75
Shanghai Hong-chuang Pharma Tech Co., Ltd.	18151128828	hc-sales@foxmail.com	China	2635	55
Shanghai Toplab Chemical Co., Ltd.	021-31137757-00; 18121466954;18121466954	28328681@qq.com	China	184	55
Hebei Maison Chemical Co.,Ltd.	155-11852758; 18408670720	ruby@maisonchem.com.cn	China	687	58
Fengcheng Meditech (Tianjin)Co., Ltd	022-59002498-8008; 15122574756	info@fcmeditech.com	China	83	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
New Energy Chemicals	0515-82159099 13770142076	info@njuchem.com	China	251	65

Supplier	Advantage
Nanjing Habo Medical Technology Co., Ltd.	60
Suzhou Highfine Biotech Co., Ltd	75
Shanghai Hong-chuang Pharma Tech Co., Ltd.	55
Shanghai Toplab Chemical Co., Ltd.	55
Hebei Maison Chemical Co.,Ltd.	58
Fengcheng Meditech (Tianjin)Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
3B Pharmachem (Wuhan) International Co.,Ltd.	69
New Energy Chemicals	65

View Latest Price from 2-Bromopyridine-5-carbaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	6-Bromonicotinaldehyde 149806-06-4	$1.00-200.00	1KG	99%, 99.5% Sublimated		Henan Fengda Chemical Co., Ltd
2026-08-20	2-Bromopyridine-5-carbaldehyde 149806-06-4	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2026-07-29	2-Bromopyridine-5-carbaldehyde 149806-06-4		1KG	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd

6-Bromonicotinaldehyde
149806-06-4
$1.00-200.00
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

2-Bromopyridine-5-carbaldehyde
149806-06-4
$1.10
99.00%
Dideu Industries Group Limited

2-Bromopyridine-5-carbaldehyde
149806-06-4
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

2-Bromopyridine-5-carbaldehyde Spectrum

2-Bromopyridine-5-carbaldehyde(149806-06-4)¹HNMR 2-Bromopyridine-5-carbaldehyde(149806-06-4)FT-IR

149806-06-4 (2-Bromopyridine-5-carbaldehyde) Related Search:

3-Aminopyridine 4-Methylpyridine Chromium picolinate Sulfasalazine 1-Hexadecylpyridinium bromide

2-Carboxybenzaldehyde 2-Bromopyridine t-butyl 6-bromo-3-pyridinecarboxylate N-methyl 2-bromo-5-pyridinecarboxamide 5-Bromo-3-pyridinecarboxaldehyde

Methyl 6-bromonicotinate 5-Acetyl-2-bromopyridine 2-Bromo-5-formyl-3-methylpyridine 6-Bromonicotinic acid 6-Bromonicotinamide

5,6-Dibromopyridine-3-carboxylic acid 2-Bromopyridine-4-carbaldehyde ,97%,2-BROMOPYRIDINE-4-CARBALDEHYDE N-ethyl 2-bromo-5-pyridinecarboxamide

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2-BROMOPYRIDINE-5-CARBALDEHYDE 2-BROMOPYRIDINE-5-CARBOXALDEHYDE 2-BROMO-5-PYRIDINECARBOXALDEHYDE 6-BROMOPYRIDINE-3-CARBOXALDEHYDE 6-BROMO-3-PYRIDINECARBOXALDEHYDE 2-BROMO-5-FORMYLPYRIDINE97+% 6-Bromo-3-pyridinecarboxaldehyde,95% 6-Bromopyridine-3-carboxaldehyde, 6-Bromo-3-formylpyridine 2-Bromo-5-formylpyridine 6-Bromonicotinaldehyde 2-BroMopridine-5-carbaldehyde 3-Pyridinecarboxaldehyde,6-broMo- 6-BroMo-3-pyridinecarboxaldehyde, 98%, 98% 6-Bromo-3-pyridinecarboxaldehyde 95% 6-Bromopyridine-3-carboxaldehyde, 2-Bromo-5-formylpyridine 6-Bromo-3-pyridinecarboxaldehyde > 6-Bromopyridine-3-carboxaldehyde, 98%, for synthesis 2-Bromo-5-aldopyridine 6-Bromo-3-pyridinecarboxaL 2-Bromopyridine-5-carbaldehyde ISO 9001：2015 REACH TIANFU CHEM-- 2-Bromopyridine-5-carbaldehyde 2- bromo -5- aldehyde pyridine 2-BROMO-5-PYRIDINECARBOXALDEHYDEChemicalbook Abemaciclib Impurity 37 2-BROMO-5-FORMYLPYRIDINE 6-BROMO-PYRIDINE-3-CARBALDEHYDE 6-Bromo-3-pyridinecarbaldehyde 6-BROMONICOTINALDEHYDE 2-bromopyridine-5-formaldehyde 149806-06-4 34160-40-3 Heterocyclic Building Blocks Halogenated Heterocycles Pyridines Building Blocks Heterocycle-Pyridine series C1 to C6 C5 to C6 C6 to C7 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Organic Building Blocks Bases & Related Reagents Nucleotides C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridine Series pharmacetical Aldehydes Pyridines Aldehyde Building Blocks Nucleotides and Nucleosides Carbonyl Compounds Heterocycles Pyridine