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Z-TYR(BZL)-OH

Z-TYR(BZL)-OH Structure
Z-TYR(BZL)-OH structure
CAS No.
16677-29-5
Chemical Name:
Z-TYR(BZL)-OH
Synonyms
Z-TYR(BZL)-OH;CBZ-TYR(BZL)-OH;Z-L-Tyr(Bzl)-OH;Cbz-L-Tyr(Bzl)-OH;CBZ-O-BENZYL-L-TYR;Z-TYROSINE(BZL)-OH;Z-O-BENZYL-L-TYROSINE;CBZ-O-BENZYL-L-TYROSINE;Z-O-Benzyl-L-tyrosine, 98%+;N-ALPHA-CBZ-O-BENZYL-L-TYROSINE
CBNumber:
CB3175990
Molecular Formula:
C24H23NO5
Molecular Weight:
405.44
MDL Number:
MFCD00037819
MOL File:
16677-29-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-20 15:44:34
Product description Number Pack Size Price
Z-O-benzyl-L-tyrosine ≥98%(HPLC) 02269 1G $22.83
Z-O-benzyl-L-tyrosine ≥98%(HPLC) 02269 5G $64.8
Z-O-benzyl-L-tyrosine ≥98%(HPLC) 02269 25G $243.77
Z-O-benzyl-L-tyrosine ≥98%(HPLC) 02269 100G $599.2
Z-O-benzyl-L-tyrosine ≥98%(HPLC) 02269 250G $1145.72
More product size
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Z-TYR(BZL)-OH Properties

Boiling point 624.4±55.0 °C(Predicted)
Density 1.249±0.06 g/cm3(Predicted)
storage temp. Store at 0°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Solid
pka 2.98±0.10(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3
NFPA 704
1
0 0

Z-TYR(BZL)-OH price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Chem-Impex 02269 Z-O-benzyl-L-tyrosine ≥98%(HPLC) 16677-29-5 1G $22.83 2026-05-19 Buy
Chem-Impex 02269 Z-O-benzyl-L-tyrosine ≥98%(HPLC) 16677-29-5 5G $64.8 2026-05-19 Buy
Chem-Impex 02269 Z-O-benzyl-L-tyrosine ≥98%(HPLC) 16677-29-5 25G $243.77 2026-05-19 Buy
Chem-Impex 02269 Z-O-benzyl-L-tyrosine ≥98%(HPLC) 16677-29-5 100G $599.2 2026-05-19 Buy
Chem-Impex 02269 Z-O-benzyl-L-tyrosine ≥98%(HPLC) 16677-29-5 250G $1145.72 2026-05-19 Buy
Product number Packaging Price Buy
02269 1G $22.83 Buy
02269 5G $64.8 Buy
02269 25G $243.77 Buy
02269 100G $599.2 Buy
02269 250G $1145.72 Buy

Z-TYR(BZL)-OH Chemical Properties,Uses,Production

Synthesis

H-TYR(BZL)-OH

16652-64-5

Benzyl chloroformate

501-53-1

Tyrosine, N-[(phenylmethoxy)carbonyl]-O-(phenylmethyl)-

86827-18-1

General procedure for the synthesis of the compound (CAS: 86827-18-1) from O-benzyl-L-tyrosine and benzyl chloroformate: (S)-O-benzyl-tyrosine (8.14 g, 30 mmol) was dissolved in THF (60 mL) and cooled to 0 °C. Subsequently, an aqueous solution of NaOH (3 g, 75 mmol) was added (60 mL). A solution of benzyl chloroformate (4.65 mL, 5.63 g, 33 mmol) in THF (30 mL) was slowly added dropwise at 0 °C. The reaction mixture was stirred at 0 °C for 2 h, then gradually warmed to room temperature and continued stirring overnight. After the reaction was completed, water (50 mL) was added and the pH was adjusted to 1-2 with 10% HCl, then the aqueous phase was extracted with EtOAc (3 × 100 mL). The organic phases were combined, washed with brine (2 × 100 mL) and dried over Na2SO4. The solvent was removed by concentration under reduced pressure to give pure (S)-N-Benzyloxycarbonyl-O-benzyl-tyrosine (11.57 g, 95% yield) as a pale yellow solid, melting point: 128-130°C. The product could be used in the next reaction without further purification.1H NMR (400 MHz, CDCl3) δ: 2.85 (dd, J = 13.2, 8.4 Hz, 1H, CH2), 3.10 (dd, J = 13.2, 12.0 Hz, 1H, CH2), 4.43 (dd, J = 12.0, 8.4 Hz, 1H, CH). 4.80 (d, J = 12.4 Hz, 1H, CH2O), 4.82 (s, 2H, CH2O), 5.00 (d, J = 12.4 Hz, 1H, CH2O), 5.60 (d, J = 4.8 Hz, 1H, NH), 6.65-7.35 (m, 14H, ArH).13C NMR (100 MHz, CDCl3) δ : 36.9, 56.2, 66.8, 69.8, 114.8, 127.5, 127.83, 127.89, 127.93, 128.4, 128.5, 128.9, 130.3, 136.2, 137.0, 156.6, 157.7, 177.5. HRMS (ESI) C24H24NO5 [M + H ]+ m/z calculated value: 406.1649; measured value: 406.1641.

References

[1] Tetrahedron, 2014, vol. 70, # 34, p. 5197 - 5206
[2] Chemische Berichte, 1958, vol. 91, p. 542,546
[3] Monatshefte fuer Chemie, 1974, vol. 105, p. 1110 - 1135

Z-TYR(BZL)-OH Preparation Products And Raw materials

Raw materials

Z-TYR-OH H-TYR(BZL)-OH Benzyl chloroformate Benzyl bromide Water
Sodium hydroxide Tetrahydrofuran

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Preparation Products

Z-TYR(BZL)-OH Suppliers

Global( 161)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9539 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Hangzhou Go Top Peptide Biotech 		0571-88211921 sales1@gotopbio.com CHINA 2609 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
GL Biochem(Binhai) Ltd. 		58
Finetech Industry Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Hangzhou Go Top Peptide Biotech 		58

View Lastest Price from Z-TYR(BZL)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Z-TYR(BZL)-OH pictures 2019-07-06 Z-TYR(BZL)-OH
16677-29-5
 US $1.00 / KG 1KG 99% 20kg Career Henan Chemical Co
Z-TYR(BZL)-OH pictures 2019-07-06 Z-TYR(BZL)-OH
16677-29-5
 US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co

16677-29-5(Z-TYR(BZL)-OH)Related Search:

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N-ALPHA-CBZ-O-BENZYL-L-TYROSINE N-ALPHA-CARBOBENZOXY-O-BENZYL L-TYROSINE N-CARBOBENZOXY-O-BENZYL-L-TYROSINE Z-O-BENZYL-L-TYROSINE Z-TYR(BZL)-OH Z-TYROSINE(BZL)-OH CBZ-(S)-2-AMINO-3-(4'-BENZYLOXYPHENYL)PROPANOIC ACID CBZ-O-BENZYL-L-TYR CBZ-O-BENZYL-L-TYROSINE CBZ-TYR(BZL)-OH BENZYLOXYCARBONYL-O-BENZYL-L-TYROSINE (2S)-2-{[(benzyloxy)carbonyl]aMino}-3-[4-(benzyloxy)phenyl]propanoic acid N-Benzyloxycarbonyl-O-benzyl-L-tyrosine N-CBZ-O-BENZYL-L-TYROSINE CRYSTALLINE N-alpha-Benzyloxycarbonyl-O-benzyl-L-tyrosine Z-L-Tyr(Bzl)-OH (S)-3-(4-(benzyloxy)phenyl)-2-(benzyloxycarbonylamino)propanoic acid Cbz-L-Tyr(Bzl)-OH Z-O-benzyl-L-tyrosine≥ 98% (HPLC) (S)-2-(((Benzyloxy)carbonyl)aMino)-3-(4-(benzyloxy)phenyl)propanoic acid 2-(phenylmethoxycarbonylamino)-3-(4-phenylmethoxyphenyl)propanoic acid L-Tyrosine, N-[(phenylmethoxy)carbonyl]-O-(phenylmethyl)- Z-O-Benzyl-L-tyrosine, 98%+ Z-O-Benzyl-L-Tyrosine extrapure, 98% 16677-29-5 Amino Acid Derivatives Peptide Synthesis Specialty Synthesis Tyrosine