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3',4'-Dichloropivalanilide

CAS No.
7160-22-7
Chemical Name:
3',4'-Dichloropivalanilide
Synonyms
N-(3,4-Dichlorophenyl)pivalaMide;AURORA 5475;TIMTEC-BB SBB008104;3',4'-Dichloropivalanilide;3',4'-DICHLORO-2,2-DIMETHYLPROPIONANILIDE;3',4'-DICHLORO-2,2-DIMETHYLPROPIONANILIDE;2,2-Dimethyl-N-(3,4-dichlorophenyl)propanamide;N-(3,4-Dichlorophenyl)-2,2-dimethylpropanamide;N-(3,4-dichlorophenyl)2,2-dimethyl-propionamide;Propanamide, N-(3,4-dichlorophenyl)-2,2-dimethyl-
CBNumber:
CB3203631
Molecular Formula:
C11H13Cl2NO
Molecular Weight:
246.13
MDL Number:
MFCD00043462
MOL File:
7160-22-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:46

3',4'-Dichloropivalanilide Properties

storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H411-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P
RIDADR  UN3077
HazardClass  9
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

3',4'-Dichloropivalanilide price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S902667 3'',4''-DICHLORO-2,2-DIMETHYLPROPIONANILIDE AldrichCPR 7160-22-7 50MG $121 2026-04-30 Buy
Activate Scientific AS49881 N-(3,4-Dichlorophenyl)pivalamide 95% 7160-22-7 1g $76 2026-06-04 Buy
Activate Scientific AS49881 N-(3,4-Dichlorophenyl)pivalamide 95% 7160-22-7 5g $229 2026-06-04 Buy
Matrix Scientific 172215 3',4'-Dichloropivalanilide 7160-22-7 2.00g $100 2026-05-18 Buy
Synthonix D54660 N-(3,4-Dichlorophenyl)pivalamide 95+% 7160-22-7 250mg $142 2026-05-06 Buy
Product number Packaging Price Buy
S902667 50MG $121 Buy
AS49881 1g $76 Buy
AS49881 5g $229 Buy
172215 2.00g $100 Buy
D54660 250mg $142 Buy

3',4'-Dichloropivalanilide Chemical Properties,Uses,Production

Synthesis

Pivaloyl chloride

3282-30-2

3,4-Dichloroaniline

95-76-1

3',4'-DICHLOROPIVALANILIDE

7160-22-7

The general procedure for the synthesis of 3-chloro-2-(chloromethyl)-2-methyl-N-phenylpropionamide from pivaloyl chloride and 3,4-dichloroaniline was carried out as follows: firstly, the preparation of N-(3,4-dichlorophenyl)-2,2-dimethylpropionamide was carried out. 3,4-Dichloroaniline (150 g) was dissolved in tert-butyl methyl ether (TBME, 1 L) and the solution was cooled to 10-15 °C. Under vigorous stirring, 30% aqueous sodium hydroxide solution (141 g, 1.14 eq.) was slowly added, followed by dropwise addition of pivaloyl chloride (PivCl, 126 mL) at a rate that controlled the internal temperature to not exceed 30°C. During the dropwise addition, the reaction mixture gradually thickened and precipitated a white solid product. After completion of the dropwise addition (about 10-15 minutes), the reaction mixture was heated to 30-35°C and maintained for 1 hour, followed by cooling to room temperature. The mixture was placed at -5°C overnight and then filtered. The filter cake was washed sequentially with a 90:10 water/methanol mixture (600 mL) and water (900 mL). Finally, it was dried under vacuum to give 195 g (86% yield) of off-white crystalline product.LCMS analysis showed m/z 246 (M-H)+.

References

[1] Patent: US2003/216375, 2003, A1
[2] Patent: US2003/50298, 2003, A1
[3] Patent: US2003/55286, 2003, A1
[4] Patent: US2004/48897, 2004, A1

3282-30-2
95-76-1
7160-22-7
Synthesis of 3',4'-Dichloropivalanilide from Pivaloyl chloride and 3,4-Dichloroaniline

3',4'-Dichloropivalanilide Preparation Products And Raw materials

3',4'-Dichloropivalanilide Suppliers

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Taizhou Tongxin Bio-Tech Co., Ltd 0523-86818997 18652728585 sales@allyrise.com China 2986 60
Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd 18210788515; 18210788515 zhuzixin999@163.c0m China 4998 55
ShangHai Angti Biotechnology Co., Ltd. 13764913901 info@angtibio.com China 4975 55
Chengdu Xiaojia Technology Co., Ltd. 15902830537 zhanghao@happysyn.com China 2365 55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
Shanghai Moss Medicine Technology Co., Ltd. +86-188369842 +86-15618151133 188369842@qq.com China 1965 58
Labnetwork lnc. +86-27-50766799 +86-18062016861 contact@labnetwork.com China 19981 58

View Lastest Price from 3',4'-Dichloropivalanilide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3',4'-DICHLOROPIVALANILIDE pictures 2026-06-30 3',4'-DICHLOROPIVALANILIDE
7160-22-7
1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
TIMTEC-BB SBB008104 AURORA 5475 N-(3,4-Dichlorophenyl)-2,2-dimethylpropanamide 2,2-Dimethyl-N-(3,4-dichlorophenyl)propanamide N-(3,4-dichlorophenyl)2,2-dimethyl-propionamide Propanamide, N-(3,4-dichlorophenyl)-2,2-dimethyl- 3',4'-DICHLORO-2,2-DIMETHYLPROPIONANILIDE 3',4'-DICHLORO-2,2-DIMETHYLPROPIONANILIDE N-(3,4-Dichlorophenyl)pivalaMide 3',4'-Dichloropivalanilide 7160-22-7