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2-Amino-5-bromo-6-methylpyridine

2-Amino-5-bromo-6-methylpyridine Structure
2-Amino-5-bromo-6-methylpyridine structure
CAS No.
42753-71-9
Chemical Name:
2-Amino-5-bromo-6-methylpyridine
Synonyms
5-BROMO-6-METHYLPYRIDIN-2-AMINE;6-AMINO-3-BROMO-2-PICOLINE;5-BROMO-6-METHYL-PYRIDIN-2-YLAMINE;ASISCHEM W51193;BUTTPARK 43\57-95;AKOS BBS-00004445;TIMTEC-BB SBB000260;6-Amino-3-bromo-2-methyL;2-AMINO-5-BROMO-6-PICOLINE;5-fluoro-2-pyridin-2-amine
CBNumber:
CB8188979
Molecular Formula:
C6H7BrN2
Molecular Weight:
187.04
MDL Number:
MFCD00068230
MOL File:
42753-71-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:26:58
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2-Amino-5-bromo-6-methylpyridine Properties

Melting point 79-84 °C(lit.)
Boiling point 234.3±35.0 °C(Predicted)
Density 1.5672 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 4.80±0.37(Predicted)
form Fluffy Powder
color White to off-white
Sensitive Hygroscopic
BRN 114140
InChI InChI=1S/C6H7BrN2/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3,(H2,8,9)
InChIKey SEOZHXRTVJPQPZ-UHFFFAOYSA-N
SMILES C1(N)=NC(C)=C(Br)C=C1
CAS DataBase Reference 42753-71-9(CAS DataBase Reference)
FDA UNII DU7SD24F59
EPA Substance Registry System 2-Pyridinamine, 5-bromo-6-methyl- (42753-71-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-26/37/39
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29333999
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
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2-Amino-5-bromo-6-methylpyridine price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 548405 6-Amino-3-bromo-2-methylpyridine 97% 42753-71-9 5g $48.7 2023-06-20 Buy
TCI Chemical A1889 6-Amino-3-bromo-2-methylpyridine >98.0%(GC)(T) 42753-71-9 1g $18 2026-04-30 Buy
TCI Chemical A1889 6-Amino-3-bromo-2-methylpyridine >98.0%(GC)(T) 42753-71-9 5g $71 2026-04-30 Buy
Usbiological 264351 5-Bromo-6-methylpyridiN-2-amiNe Asreported 42753-71-9 25g $319 2026-06-03 Buy
Usbiological 264351 5-Bromo-6-methylpyridiN-2-amiNe Asreported 42753-71-9 50g $429 2026-06-03 Buy
Product number Packaging Price Buy
548405 5g $48.7 Buy
A1889 1g $18 Buy
A1889 5g $71 Buy
264351 25g $319 Buy
264351 50g $429 Buy

2-Amino-5-bromo-6-methylpyridine Chemical Properties, Uses, Production

Application

2-Amino-5-bromo-6-methylpyridine is an important chemical raw material or intermediate, widely used in the synthesis of pyridine drugs, and also has potential effects such as antibacterial, antidepressant, insecticidal, herbicidal, and antimicrobial properties.

Chemical Properties

Light yellow Cryst

Synthesis

2-Bromo-3-methylpyridine

3430-17-9

2-Amino-5-bromo-6-methylpyridine

42753-71-9

General steps: Example 2 Add 650 g of xylene as solvent to the reactor and heat to 115-120°C. The heating was continued under reflux conditions until the water was completely removed. The solvent was cooled to 70°C under nitrogen protection. Subsequently, 22 g of sodium amide was added and the solution was heated to 118-120 °C. Under reflux condition, 102 g of 2-bromo-3-methylpyridine was slowly added dropwise, and after completion of the dropwise addition, the reaction temperature was maintained at reflux for 1 hour. Upon completion of the reaction, the reaction solution was cooled to 45 °C. The reaction solution was then poured into ice water and the upper organic phase was separated. The xylene was concentrated under atmospheric pressure to 220 g remaining and cooled to 10-15 °C with stirring. After crystallization, 100 g of the target product 2-amino-5-bromo-6-methylpyridine was obtained with 99.3% purity and 90.1% yield.

References

[1] Patent: CN105348181, 2016, A. Location in patent: Paragraph 0023; 0024; 0025

2-Amino-5-bromo-6-methylpyridine synthesis

3430-17-9
42753-71-9
Synthesis of 2-Amino-5-bromo-6-methylpyridine from 2-Bromo-3-methylpyridine

2-Amino-5-bromo-6-methylpyridine Preparation Products And Raw materials

Raw materials

Fuming sulfuric acid 2-Amino-6-methylpyridine Ethyl acetate Bromine Dichloromethane
Sodium hydroxide Petroleum ether Sulfuric acid 2-Amino-3-bromo-6-methylpyridine 2-Amino-3,5-dibromo-6-methylpyridine

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Preparation Products

2-Acetylamino-5-bromo-6-methylpyridine 6-Acetamido-3-bromopicolinic acid 3-Bromo-6-chloro-2-methylpyridine Ethyl 6-chloro-2-methylpyridine-3-carboxylate 2-methyl-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuro[2,3-b]pyridine
ethyl {[(5-bromo-6-methylpyridin-2-yl)amino]carbonothioyl}carbamate 5-broMo-N,N,6-triMethylpyridin-2-aMine

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2-Amino-5-bromo-6-methylpyridine Suppliers

Global Suppliers ( 470)
Supplier Tel Email Country ProdList Advantage
Sanjing New Materials Technology (Taizhou) Co., Ltd. 13852622638 1048979734@qq.com China 778 58
Nanjing Sifanke Chemical Co.LTD 025-58699658 13814094318 985496172@qq.com China 511 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Liaoning Tianhua Chemical Co., Ltd. 0418-6530555 2855550 China 338 69
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Sanjing New Materials Technology (Taizhou) Co., Ltd. 58
Nanjing Sifanke Chemical Co.LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Liaoning Tianhua Chemical Co., Ltd. 69
INTATRADE GmbH 66
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61

View Latest Price from 2-Amino-5-bromo-6-methylpyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-5-bromo-6-methylpyridine pictures 2026-09-02 2-Amino-5-bromo-6-methylpyridine
42753-71-9
 $5.00 1KG 98% Henan Fengda Chemical Co., Ltd
2-Amino-5-bromo-6-methylpyridine pictures 2026-08-20 2-Amino-5-bromo-6-methylpyridine
42753-71-9
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Amino-5-bromo-6-methylpyridine pictures 2026-06-30 2-Amino-5-bromo-6-methylpyridine
42753-71-9
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

2-Amino-5-bromo-6-methylpyridine Spectrum

2-Amino-5-bromo-6-methylpyridine(42753-71-9)1HNMR2-Amino-5-bromo-6-methylpyridine(42753-71-9)IR

42753-71-9 (2-Amino-5-bromo-6-methylpyridine) Related Search:

2-Aminopyridine 2-Bromo-6-methylpyridine 4-Dimethylaminopyridine 6-Aminocaproic acid Dibenzylamine
1-Hexadecylpyridinium bromide Triallylamine 2-Amino-5-methylpyridine Bis(2-ethylhexyl)amine 2,6-Lutidine
2-Amino-5-bromopyridine 2-Picoline 2-Amino-6-methylpyridine 3-Aminophenol Tris(hydroxymethyl)aminomethane
Glycine Aminoethoxyvinyl glycine hydrochloride 3-Aminopyridine

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6-Amino-3-bromo-2-methylpyridine ,98% 2-Methyl-3-bromo-6-aminopyridine 5-Bromo-6-methyl-2-pyridinamine 5-Bromo-6-methylpyridine-2-amine 2-amine-5-bromo-6-methylpyridine 2 - aMino - 5 - broMine - 6 - Methyl pyridine 6-Amino-3-bromo-2-methylpyridine,97% 6-Amino-3-bromo-2-picoline,98% JR-8257, 6-Amino-3-bromo-2-methylpyridine, 97% 5-bromo-6-methyl-2-pyridinamin BUTTPARK 43\57-95 ASISCHEM W51193 TIMTEC-BB SBB000260 AKOS BBS-00004445 5-BROMO-6-METHYL-PYRIDIN-2-YLAMINE 6-AMINO-3-BROMO-2-METHYLPYRIDINE 6-AMINO-3-BROMO-2-PICOLINE 2-AMINO-5-BROMO-6-METHYLPYRIDINE 2-AMINO-5-BROMO-6-PICOLINE 2-AMINO-5-BROMO-6-METHYPYRIDINE 5-bromo-6-methylpyrdin-2-amine 5-fluoro-2-pyridin-2-amine 2-Amino-5-bromo-ALPHA-picoline 6-AMINO-3-BROMO-2-PICOLINE 98% 6-AMINO-3-BROMO-2-PICOLINE (6-AMINO-3-BROMO-2-METHYLPYRIDINE) 6-Amino-3-bromo-2-methylpyridine > 6-Amino-3-bromo-2-methyL 2-Pyridinamine, 5-bromo-6-methyl- 2-Amino-5-bromo-6-methylpyridine ISO 9001：2015 REACH 6-Amino-3-bromo-2-methylpyridine, 95 5-BROMO-6-METHYLPYRIDIN-2-AMINE 42753-71-9 C6H7BrN2 Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Bromopyridines Halopyridines Heterocycle-Pyridine series Amino-pyridine series Halopyridines C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines, Pyrimidines, Purines and Pteredines blocks Bromides Pyridines Pyridine Amines and Anilines Heterocycles Bromopyridines Amines compounds of pyridine