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Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester

CAS No.
2093934-94-0
Chemical Name:
Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester
Synonyms
DBCO-PEG12-NHS Ester;DBCO-PEG12-SPA;DBCO-NH-PEG12-CH2CH2COONHS ester;Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester;Poly(oxy-1,2-ethanediyl), α-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethyl]-ω-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]-
CBNumber:
CB33309389
Molecular Formula:
(C2H4O)nC28H27N3O7
Molecular Weight:
0
MDL Number:
MOL File:
2093934-94-0.mol
MSDS File:
SDS
Last updated:2026-07-17 09:03:53
Product description Number Pack Size Price
DBCO-PEG12-NHS ester 95% bp-24149 25MG $380
DBCO-PEG12-NHS ester 95% bp-24149 50MG $650
DBCO-PEG12-NHS ester 95% bp-24149 100MG $960
DBCO-PEG12-NHS ester 95% bp-24149 250MG $1850
Poly(oxy-1,2-ethanediyl), α-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethyl]-ω-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]- ≥98% AA01JOTA 25mg $400

Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester Properties

storage temp. -20°C, protect from light, stored under nitrogen
solubility Soluble in DMSO, DCM, DMF
form Oil
color Colorless to light yellow

Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm bp-24149 DBCO-PEG12-NHS ester 95% 2093934-94-0 25MG $380 2026-05-24 Buy
BroadPharm bp-24149 DBCO-PEG12-NHS ester 95% 2093934-94-0 50MG $650 2026-05-24 Buy
BroadPharm bp-24149 DBCO-PEG12-NHS ester 95% 2093934-94-0 100MG $960 2026-05-24 Buy
BroadPharm bp-24149 DBCO-PEG12-NHS ester 95% 2093934-94-0 250MG $1850 2026-05-24 Buy
aablocks AA01JOTA Poly(oxy-1,2-ethanediyl), α-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethyl]-ω-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]- ≥98% 2093934-94-0 25mg $400 2026-05-30 Buy
Product number Packaging Price Buy
bp-24149 25MG $380 Buy
bp-24149 50MG $650 Buy
bp-24149 100MG $960 Buy
bp-24149 250MG $1850 Buy
AA01JOTA 25mg $400 Buy

Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester Chemical Properties,Uses,Production

Description

DBCO-PEG12-NHS Ester is a monodisperse PEG linker which enable free copper click chemistry with N3 group. NHS ester moiety can react specifically and efficiently with primary amines to form a covalent amide bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation.

Uses

DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
XIAMEN SINOPEG BIOTECH CO., LTD.
+86-0592-7761068 15616186207 changaiwei@sinopeg.com China 1133 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3147 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 38999 58
Jilin Chinese Academy of Sciences-yanshen Technology
18143011203 info@chemextension.com China 42052 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 1924344760@confluore.cn China 2996 58
Aladdin Scientific
tp@aladdinsci.com United States 50108 58
Shanghai Send Pharmaceutical Technology Co., Ltd. 58088081 18317173152 sale1@shsendpharm.com China 846 55
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80534353 19917294565 et@chemextension.com China 3862 55
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518 shyysw007@163.com China 89667 60

View Lastest Price from Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DBCO-PEG12-NHS pictures 2026-07-24 DBCO-PEG12-NHS
2093934-94-0
1g 98% 1g/bottle, 10g/bottle, 100g/bottle XIAMEN SINOPEG BIOTECH CO., LTD.
DBCO-PEG12-NHS ester pictures 2026-07-17 DBCO-PEG12-NHS ester
2093934-94-0
10g TargetMol Chemicals Inc.
DBCO-PEG12-NHS ester pictures 2025-06-07 DBCO-PEG12-NHS ester
2093934-94-0
25mg >99.00% 100mg Xian confluore Biological Technology Co., Ltd.

Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester Spectrum

Azadibenzocyclooctyne-PEG12-N-hydroxysuccinimidyl ester DBCO-NH-PEG12-CH2CH2COONHS ester Poly(oxy-1,2-ethanediyl), α-[2-[[4-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1,4-dioxobutyl]amino]ethyl]-ω-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]- DBCO-PEG12-NHS Ester DBCO-PEG12-SPA 2093934-94-0