3-BROMO-4-FORMYLPYRIDINE
- CAS No.
- 70201-43-3
- Chemical Name:
- 3-BROMO-4-FORMYLPYRIDINE
- Synonyms
- 3-BROMOISONICOTINALDEHYDE;CHEMBRDG-BB 4003258;3-BROMO-4-FORMYLPYRIDI;3-BROMO-4-FORMYLPYRIDINE;3-Bromoisonicotinaldehyde 95%;3-Bromo-4-pyridinecarbaldehyde;3-Bromoisonicotinaldehyde ,98%;3-BROMO-PYRIDINE-4-CARBALDEHYDE;3-BROMO-4-PYRIDINECARBOXALDEHYDE;5-BroMopyridine-4-carboxaldehyde
- CBNumber:
- CB3351242
- Molecular Formula:
- C6H4BrNO
- Molecular Weight:
- 186.01
- MDL Number:
- MFCD05864506
- MOL File:
- 70201-43-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Bromo-4-pyridinecarboxaldehyde 97% | 638285 | 5g | $222 |
| 3-Bromo-4-pyridinecarboxaldehyde 97% | 638285 | 1g | $77.8 |
| 3-Bromopyridine-4-carboxaldehyde | B2624 | 1G | $32 |
| 3-Bromopyridine-4-carboxaldehyde | B2624 | 5G | $126 |
| 3-Bromo-4-pyridinecarboxaldehyde Asreported | 264417 | 1g | $408 |
| More product size | |||
| Melting point | 81-82 °C(lit.) |
|---|---|
| Boiling point | 246.2±20.0 °C(Predicted) |
| Density | 1.683±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly) |
| form | Solid |
| pka | 0.90±0.18(Predicted) |
| color | Light Brown |
| InChI | 1S/C6H4BrNO/c7-6-3-8-2-1-5(6)4-9/h1-4H |
| InChIKey | NOBDKWLIAQKADB-UHFFFAOYSA-N |
| SMILES | [H]C(=O)c1ccncc1Br |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H317-H319 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/38-43 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
3-BROMO-4-FORMYLPYRIDINE price More Price(103)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 638285 | 3-Bromo-4-pyridinecarboxaldehyde 97% | 70201-43-3 | 5g | $222 | 2026-04-30 | Buy |
| Sigma-Aldrich | 638285 | 3-Bromo-4-pyridinecarboxaldehyde 97% | 70201-43-3 | 1g | $77.8 | 2023-01-07 | Buy |
| TCI Chemical | B2624 | 3-Bromopyridine-4-carboxaldehyde | 70201-43-3 | 1G | $32 | 2026-04-30 | Buy |
| TCI Chemical | B2624 | 3-Bromopyridine-4-carboxaldehyde | 70201-43-3 | 5G | $126 | 2026-04-30 | Buy |
| Usbiological | 264417 | 3-Bromo-4-pyridinecarboxaldehyde Asreported | 70201-43-3 | 1g | $408 | 2026-06-03 | Buy |
3-BROMO-4-FORMYLPYRIDINE Chemical Properties,Uses,Production
Chemical Properties
Off-white solid
Uses
3-Bromo-4-pyridinecarboxaldehyde acts as a reagent in the synthesis of 3,4,5-trisubstituted 4,5-dihydro-1,2,4-oxadiazoles agonists which interact with the G-protein-coupled bile acid receptor 1 (TGR5) inducing insulin secretion which may be used as a potential treatment for diabetus mellitus.
Synthesis
626-55-1
68-12-2
70201-43-3
Diisopropylamine (27.6 g, 273.0 mmol) was dissolved in tetrahydrofuran (300 mL) under nitrogen protection and cooled to -78 °C. A tetrahydrofuran solution of n-butyllithium (91 mL, 228.0 mmol, 2.5 M) was slowly added dropwise and stirred at -78 °C for 1 hour. Subsequently, 3-bromopyridine (30.0 g, 190.0 mmol) was added dropwise and stirring was continued at -78 °C for 20 min. Next, N,N-dimethylformamide (55.0 g, 760.0 mmol) was added dropwise and stirred at -78 °C for 1 hour. After completion of the reaction, the mixture was slowly warmed to room temperature and the reaction was quenched with saturated aqueous ammonium chloride solution (150 mL). The aqueous layer was extracted with ethyl acetate (200 mL x 3), and the organic layers were combined and concentrated in vacuum. The residue was purified by silica gel column chromatography to afford 3-bromopyridine-4-aldehyde (12.0 g, 34.0% yield). The product was confirmed by 1H NMR (400 MHz, CD3OD): δ 10.37 (s, 1H), 8.91 (s, 1H), 8.80-8.61 (m, 1H), 7.78-7.63 (m, 1H).LCMS (m/z): 187.0 (M + 1).
References
[1] Tetrahedron, 2000, vol. 56, # 3, p. 397 - 406
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 11, p. 3146 - 3151
[3] Patent: WO2015/200677, 2015, A2. Location in patent: Paragraph 00504; 00505
[4] Tetrahedron Letters, 1983, vol. 24, # 32, p. 3291 - 3294
[5] Synthesis, 1999, # 2, p. 306 - 311
3-BROMO-4-FORMYLPYRIDINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
View Lastest Price from 3-BROMO-4-FORMYLPYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-21 | 3-BROMO-4-FORMYLPYRIDINE
70201-43-3
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
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2025-11-18 | 3-BROMO-4-FORMYLPYRIDINE
70201-43-3
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
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2020-05-13 | 3-Bromopyridine-4-carboxaldehyde
70201-43-3
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-

- 3-BROMO-4-FORMYLPYRIDINE
70201-43-3
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- 3-BROMO-4-FORMYLPYRIDINE
70201-43-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- 3-Bromopyridine-4-carboxaldehyde
70201-43-3
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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