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5-Bromopyridine-2-carbaldehyde

5-Bromopyridine-2-carbaldehyde structure

CAS No.: 31181-90-5

Chemical Name:: 5-Bromopyridine-2-carbaldehyde

Synonyms: 5-BROMOPICOLINALDEHYDE;5-BROMO-2-PYRIDINECARBOXALDEHYDE;5-BROMO-PYRIDINE-2-CARBALDEHYDE;2-Formyl-5-Bromopyridine;5-Bromo-2-formylpyridine, 5-Bromo-2-picolinaldehyde;5-BROMO-2-FORMYLPYRIDINE;5-Bromopyridine-2-carbaL;5-Bromo-2-picolinaldehyde;5-Bromo-2-Pyridinaldehyde;5-BroM-3-pyridincarbaldehyd

CBNumber:: CB8352244

Molecular Formula:: C6H4BrNO

Molecular Weight:: 186.01

MDL Number:: MFCD04112535

MOL File:: 31181-90-5.mol

MSDS File:: SDS

Last updated:2025-08-18 19:12:29

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5-Bromopyridine-2-carbaldehyde Properties

Melting point	91-96 °C
Boiling point	70°C/26mmHg(lit.)
Density	1.683±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	1.36±0.10(Predicted)
form	powder to crystal
color	White to Light yellow to Light orange
Water Solubility	Insoluble in water.
Sensitive	Air Sensitive
InChI	InChI=1S/C6H4BrNO/c7-5-1-2-6(4-9)8-3-5/h1-4H
InChIKey	ZQVLPMNLLKGGIU-UHFFFAOYSA-N
SMILES	C1(C=O)=NC=C(Br)C=C1
CAS DataBase Reference	31181-90-5(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38-20/21/22

Safety Statements

22-26-36/37/39-36

WGK Germany

HazardClass

IRRITANT

HS Code

29333990

NFPA 704

	1
2		0

5-Bromopyridine-2-carbaldehyde price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	694177	5-Bromo-2-pyridinecarboxaldehyde 95%	31181-90-5	1g	$84.2	2025-07-31	Buy
TCI Chemical	B3489	5-Bromo-2-pyridinecarboxaldehyde >98.0%(GC)	31181-90-5	1g	$30	2025-07-31	Buy
Oakwood	040402	5-Bromopyridine-2-carbaldehyde	31181-90-5	5g	$30	2021-12-16	Buy
SynQuest Laboratories	4H15-9-01	5-Bromo-2-formylpyridine 98%	31181-90-5	25g	$80	2021-12-16	Buy
AK Scientific	0643AP	5-Bromopyridine-2-carbaldehyde,tech.	31181-90-5	100g	$120	2021-12-16	Buy

Product number	Packaging	Price	Buy
694177	1g	$84.2	Buy
B3489	1g	$30	Buy
040402	5g	$30	Buy
4H15-9-01	25g	$80	Buy
0643AP	100g	$120	Buy

5-Bromopyridine-2-carbaldehyde Chemical Properties,Uses,Production

Chemical Properties

Light yellow Cryst

Uses

5-Bromopyridine-2-carboxaldehyde is used as organic chemical synthesis intermediate.

Synthesis

624-28-2

68-12-2

31181-90-5

5-Bromo-2-pyridinecarboxaldehyde was synthesized according to General Method C using 2,5-dibromopyridine and N,N-dimethylformamide (DMF) as raw materials. The specific operation was as follows: 2,5-dibromopyridine (237 mg, 1 mmol) was mixed with DMF (115 μL, 1.5 mmol) for the reaction. After completion of the reaction, the crude product was purified by fast column chromatography (eluent: hexane/ethyl acetate = 10:1) to afford the target compound 5-bromo-2-pyridinecarboxaldehyde (27b) as a brown solid (149 mg, 80% yield). Thin layer chromatography (TLC) analysis showed an Rf value of 0.45 (Expander: hexane/ethyl acetate = 8:1). Nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 400 MHz, CDCl3) data were as follows: δ 10.03 (1H, s), 8.85 (1H, dd, J = 0.8, 2.0 Hz), 8.02 (1H, ddd, J = 0.8, 2.0, 8.0 Hz), 7.85 (1H, dd, J = 0.8, 8.0 Hz). The nuclear magnetic resonance carbon spectrum (13C NMR, 100 MHz, CDCl3) data were as follows: δ 192.4, 151.7, 151.3, 140.0, 126.3, 122.8. The spectral data obtained were in agreement with literature reports.

References

[1] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 22, p. 5852 - 5869
[2] Patent: WO2007/15744, 2007, A1. Location in patent: Page/Page column 58-59
[3] Chemistry - A European Journal, 2006, vol. 12, # 13, p. 3472 - 3483
[4] Patent: WO2006/22794, 2006, A1. Location in patent: Page/Page column 49
[5] Tetrahedron Letters, 2000, vol. 41, # 22, p. 4335 - 4338

5-Bromopyridine-2-carbaldehyde synthesis

Synthesis of 5-Bromopyridine-2-carbaldehyde from 5-Bromo-2-pyridinecarbonitrile

5-Bromopyridine-2-carbaldehyde Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide 3-Chloroperoxybenzoic acid Triethylamine Chloroform Trifluoroacetic anhydride

Ethyl acetate 5-Bromo-2-methylpyridine Methanol Oxalyl chloride Sodium thiosulfate pentahydrate

2-Pyridinemethanol, 5-bromo-, 2-acetate 5-Bromo-2-(dibromomethyl)pyridine 5-Bromo-2-hydroxymethylpyridine 5-Bromo-2-pyridinecarbonitrile 2-FORMYL-5-PICOLINE

5-BROMO-2-METHYLPYRIDINE N-OXIDE 5-Bromo-2-iodopyridine

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Preparation Products

5-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER

5-Bromopyridine-2-carbaldehyde Suppliers

Global( 425)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
PNP Biotech Co. Ltd	+8618516098983	sales@pnpbiotech.com	China	1001	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	9029	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
PNP Biotech Co. Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58

View Lastest Price from 5-Bromopyridine-2-carbaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-08-18	5-Bromo-2-pyridinecarbaldehyde 31181-90-5	US $1.10-9.90 / KG	1KG	99% min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-07-25	5-Bromopyridine-2-carbaldehyde 31181-90-5	US $0.00 / kg	1kg	98%	1000kg	Shaanxi Dideu New Materials Co. Ltd
2025-06-20	5-Bromopyridine-2-carbaldehyde 31181-90-5	US $20.00-7.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.

5-Bromo-2-pyridinecarbaldehyde
31181-90-5
US $1.10-9.90 / KG
99% min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

5-Bromopyridine-2-carbaldehyde
31181-90-5
US $0.00 / kg
98%
Shaanxi Dideu New Materials Co. Ltd

5-Bromopyridine-2-carbaldehyde
31181-90-5
US $20.00-7.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

5-Bromopyridine-2-carbaldehyde Spectrum

5-Bromopyridine-2-carbaldehyde(31181-90-5)¹HNMR 5-Bromopyridine-2-carbaldehyde(31181-90-5)FT-IR

31181-90-5(5-Bromopyridine-2-carbaldehyde)Related Search:

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5-BROMOPICOLINALDEHYDE 5-BROMO-PYRIDINE-2-CARBALDEHYDE 5-BROMO-2-PYRIDINECARBALDEHYDE 5-BROMO-2-PYRIDINECARBOXALDEHYDE 5-BROMO-2-FORMYLPYRIDINE 5-BROMOPYRIDINE-2-CARBALDEHYDE(MFCD04112535) 5-Bromo-2-formylpyridine, 5-Bromo-2-picolinaldehyde 2-Formyl-5-Bromopyridine 5-Bromopyridine-2-carboxaldehyde 95% 2-FORMYL-5-BROMOPYRIDINE / 5-BROMO-2-FORMYLPYRIDINE 5-BROMO-2-PYRIDINECARBOXALDEHYDE / 5-BROMONICOTINALDEHYDE 5-Bromo-2-picolinaldehyde 2-Pyridinecarboxaldehyde, 5-bromo- 5-Bromo-2-pyridinecarboxaldehyde,5-Bromo-2-picolinaldehyde 5-BroMopyridine-2-carboxa... 5-Bromo-2-formylpyridine, 5-Bromopicolinaldehyde 5-BroM-3-pyridincarbaldehyd 5--2-broMinepyridineforMaldehyde 5-Bromopyridine-2-carboxaldehyde,99% 5-Bromo-2-pyridinecarboxaldehyde 95% 5-BROMOPYRIDINE-2-CARBOXALDEHYDE 5-Bromo-2-pyridinecarboxaldehyde > 5-Bromopyridine-2-carbaL 5-Bromopyridine-2-carboxaldeyhde 5-Bromopyridine-2-carbaldehyde ISO 9001：2015 REACH 5- bromo -2- pyridine formaldehyde 31181-90-5 5-Bromo-2-Pyridinaldehyde 31181-90-5 31181-07-2 Aldehyde pharmacetical Aldehyde Building Blocks Carbonyl Compounds Heterocycles Aldehydes blocks Bromides Pyridines Pyridine Pyridine Series 31181-90-5