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D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE

CAS No.
75590-17-9
Chemical Name:
D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE
Synonyms
DVal-Phe-Lys-CMK;PLASMIN INHIBITOR, 2HCL;valyl-phenylalanyl-lysine chloromethyl ketone;D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE;L-Phenylalaninamide, D-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]-
CBNumber:
CB3399806
Molecular Formula:
C21H33ClN4O3
Molecular Weight:
424.96
MDL Number:
MFCD00077405
MOL File:
75590-17-9.mol
Last updated:2025-06-18 16:39:34

D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Properties

Boiling point 707.0±60.0 °C(Predicted)
Density 1.160±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 5mg/mL
pka 13.06±0.46(Predicted)
form lyophilized solid
color off-white
Sequence {d-Val}-Phe-Lys-{CMK}
UNSPSC Code 12352202
NACRES NA.77

D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

D-Val-Phe-Lys-CMK (D-Val-Phe-Lys Chloromethyl ketone) can inhibit plasmin activity[1].

Biological Activity

Cell permeable: no', 'Primary Target
Human plasmin', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 100 pM for human plasmin

References

[1] F Laube, et al. Cell surface antigens in renal tumour cells: detection by immunoluminescence and enzymatic analysis. Br J Cancer. 2001 Sep 14;85(6):924-9. DOI:10.1054/bjoc.2001.2004

D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 Eric@peptidego.com China 7222 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 0571-87213919 17306812703 3007955328@qq.com China 6791 58
Merck KGaA 21-20338288 ordercn@merckgroup.com China 6394 58
D-VAL-PHE-LYS CHLOROMETHYL KETONE, DIHYDROCHLORIDE PLASMIN INHIBITOR, 2HCL valyl-phenylalanyl-lysine chloromethyl ketone L-Phenylalaninamide, D-valyl-N-[(1S)-5-amino-1-(2-chloroacetyl)pentyl]- DVal-Phe-Lys-CMK 75590-17-9 C21H33ClN4O3HCl