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H-THR(TBU)-OME HCL

H-THR(TBU)-OME HCL structure

CAS No.: 71989-43-0

Chemical Name:: H-THR(TBU)-OME HCL

Synonyms: H-Thr(tBu)-OMe;H-Thr(tBu);Methyl O-(tert-butyl)-L-threoninate hydrochloride;Thr(OtBu)-Ome.HCl;L-Thr(tBu)-OMe·HCl;H-THR(TBU)-OME HCL;H-THR(BUT)-OME HCL;H-Thr(tBu)-Ome. HC;H-L-THR(TBU)-OME HCL;THREONINE(TBU)-OME HCL

CBNumber:: CB3427653

Molecular Formula:: C9H20ClNO3

Molecular Weight:: 225.71

MDL Number:: MFCD00077111

MOL File:: 71989-43-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 06:31:42

Product description	Number	Pack Size	Price
O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)	241070	1g	$170
O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)	241070	5g	$222
O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)	241070	25g	$528
O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)	241070	100g	$1493
H-Thr(tBu)-OMe.HCl ≥98%	CS-W022753	5g	$13
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H-THR(TBU)-OME HCL Properties

storage temp.	Inert atmosphere,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Solid
color	White to off-white
BRN	4716005
InChI	InChI=1/C9H19NO3.ClH/c1-6(13-9(2,3)4)7(10)8(11)12-5;/h6-7H,10H2,1-5H3;1H/t6-,7+;/s3
InChIKey	SDHKEUUZUMQSAD-UHQDPJPENA-N
SMILES	[C@H](C)(OC(C)(C)C)[C@H](N)C(=O)OC.Cl \|&1:0,7,r\|
CAS DataBase Reference	71989-43-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

WGK Germany

NFPA 704

	1
0		0

H-THR(TBU)-OME HCL price More Price(49)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		1g	$170	2026-06-03	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		5g	$222	2026-06-03	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		25g	$528	2026-06-03	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		100g	$1493	2026-06-03	Buy
ChemScene	CS-W022753	H-Thr(tBu)-OMe.HCl ≥98%	71989-43-0	5g	$13	2026-06-04	Buy

Product number	Packaging	Price	Buy
241070	1g	$170	Buy
241070	5g	$222	Buy
241070	25g	$528	Buy
241070	100g	$1493	Buy
CS-W022753	5g	$13	Buy

H-THR(TBU)-OME HCL Chemical Properties,Uses,Production

Chemical Properties

White to off white powder

Uses

H-Thr(tBu)-OMe.HCl is a threonine derivative[1].

Synthesis

Take L-threonine methyl ester into the round bottom flask, add anhydrous ethanol and rotor in the round bottom flask, put the round bottom flask into the silicone oil heating furnace heating to 80 , when the liquid becomes uniform, add potassium hydroxide to the round bottom flask, the reaction for 1 hour the liquid from turbid to transparent, add tert-butyllithium, the liquid becomes transparent light yellow. Continue the reaction for 2 hours, the color of the liquid remained unchanged, thin-layer chromatography to detect the progress of the reaction, to be L-Threonine methyl ester reaction is complete to stop the reaction. After cooling to room temperature and filtering, a light yellow powder was obtained. In a round-bottomed flask, add anhydrous dioxane and rotor in a round-bottomed flask, L-threonine methyl ester suspended in dioxane solution, and acylation reaction with fluorenylmethoxycarbonyl azide, thin-layer chromatography to detect the progress of the reaction, to wait for the reaction of O-tert-butyl-L-threonine is complete after the reaction was stopped to obtain the crude O-tert-butyl-L-threonine methyl ester hydrochloride, extracted with ethyl acetate under the condition of pH 9-10 The crude O-tert-butyl-L-threonine methyl ester hydrochloride was extracted with ethyl acetate at pH 9-10 and refined by recrystallization.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

H-THR(TBU)-OME HCL Preparation Products And Raw materials

Raw materials

Preparation Products

H-THR(TBU)-OME HCL Suppliers

Global( 132)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6366	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
Dideu Industries Group Limited	+86-86-15536356810 +8617392712697	1022@dideu.com	China	29066	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9539	58
Hangzhou Go Top Peptide Biotech	0571-88211921	sales1@gotopbio.com	CHINA	2609	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
GenicBio Limited	58
Xiamen AmoyChem Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
GL Biochem(Binhai) Ltd.	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
Hangzhou Go Top Peptide Biotech	58

View Lastest Price from H-THR(TBU)-OME HCL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-09	H-THR(TBU)-OME HCL 71989-43-0		1KG	98%	2000	Shenzhen Nexcon Pharmatechs Ltd.

H-THR(TBU)-OME HCL
71989-43-0
98%
Shenzhen Nexcon Pharmatechs Ltd.

H-THR(TBU)-OME HCL Spectrum

H-THR(TBU)-OME HCL(71989-43-0)¹HNMR

71989-43-0(H-THR(TBU)-OME HCL)Related Search:

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O-tert-Butyl-L-serine methyl ester hydrochloride L-Threonine hydrochloride (S)-2-AMINO-3-METHOXY-PROPIONIC ACID HYDROCHLORIDE H-THR(TBU)-OH H-SER(TBU)-OME HCL

Methyl L-threoninate hydrochloride H-D-THR(TBU)-OME HCL L-SERINE METHYL ESTER O-METHYL-L-THREONINE H-THR(TBU)-OTBU HCL

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THREONINE(TBU)-OME HCL O-T-BUTYL-L-THREONINE METHYL ESTER HYDROCHLORIDE O-TERT-BUTYL-L-THREONINE METHYL ESTER HYDROCHLORIDE H-L-THR(TBU)-OME HCL H-THR(BUT)-OME HCL H-THR(TBU)-OME HCL Methyl O-(2-Methyl-2-propanyl)-L-threoninate hydrochloride (2S,3R)-Methyl 2-aMino-3-(tert-butoxy)butanoate hydrochloride O-T-Butyl-L-Threonine Methyl Ester Hydrochlorid L-Thr(tBu)-OMe·HCl O-tert-Butyl-L-threonine methyl ester hydrochloride≥ 99% (HPLC) methyl (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoate o-tert-Butyl-L-threoine methyl ester HCl methyl (2S,3R)-2-amino-3-(tert-butoxy)butanoate hydrochloride O-T-Butyl-L-ThreonineMethylEsterHydrochlori H-THR(TBU)-OME HCL USP/EP/BP methyl O-(1,1-dimethylethyl)-L-threoninate hydrochloride L-Threonine, O-(1,1-dimethylethyl)-, methyl ester, hydrochloride (1:1) H-Thr(tBu)-Ome. HC Thr(OtBu)-Ome.HCl H-Thr(tBu)-OMe H-Thr(tBu) Methyl O-(tert-butyl)-L-threoninate hydrochloride 71989-43-0 Amino Acid Derivatives Threonine Specialty Synthesis Peptide Synthesis Amino Acid Derivatives Peptide Synthesis Threonine Amino Acids ADVANCED INT.