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H-Thr(tBu)-OMe HCl

H-Thr(tBu)-OMe HCl structure

CAS No.: 71989-43-0

Chemical Name:: H-Thr(tBu)-OMe HCl

Synonyms: H-Thr(tBu)-OMe;H-Thr(tBu);Methyl O-(tert-butyl)-L-threoninate hydrochloride;Thr(OtBu)-Ome.HCl;L-Thr(tBu)-OMe·HCl;H-THR(BUT)-OME HCL;H-Thr(tBu)-Ome. HC;H-Thr(tBu)-OMe HCl;H-L-THR(TBU)-OME HCL;THREONINE(TBU)-OME HCL

CBNumber:: CB3427653

Molecular Formula:: C9H20ClNO3

Molecular Weight:: 225.71

MDL Number:: MFCD00077111

MOL File:: 71989-43-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:52:03

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H-Thr(tBu)-OMe HCl Properties

storage temp.	Inert atmosphere,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Solid
color	White to off-white
BRN	4716005
InChI	InChI=1/C9H19NO3.ClH/c1-6(13-9(2,3)4)7(10)8(11)12-5;/h6-7H,10H2,1-5H3;1H/t6-,7+;/s3
InChIKey	SDHKEUUZUMQSAD-UHQDPJPENA-N
SMILES	[C@H](C)(OC(C)(C)C)[C@H](N)C(=O)OC.Cl \|&1:0,7,r\|
CAS DataBase Reference	71989-43-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

WGK Germany

NFPA 704

	1
0		0

H-Thr(tBu)-OMe HCl price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		1g	$170	2026-06-03	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		5g	$222	2026-06-03	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		25g	$528	2026-06-03	Buy
Usbiological	241070	O-tert-Butyl-L-threonine methyl ester hydrochloride 99+% (HPLC) ≥99%(HPLC)		100g	$1493	2026-06-03	Buy
ChemScene	CS-W022753	H-Thr(tBu)-OMe.HCl ≥98%	71989-43-0	5g	$13	2026-06-04	Buy

Product number	Packaging	Price	Buy
241070	1g	$170	Buy
241070	5g	$222	Buy
241070	25g	$528	Buy
241070	100g	$1493	Buy
CS-W022753	5g	$13	Buy

H-Thr(tBu)-OMe HCl Chemical Properties, Uses, Production

Chemical Properties

White to off white powder

Uses

H-Thr(tBu)-OMe.HCl is a threonine derivative[1].

Synthesis

Take L-threonine methyl ester into the round bottom flask, add anhydrous ethanol and rotor in the round bottom flask, put the round bottom flask into the silicone oil heating furnace heating to 80 , when the liquid becomes uniform, add potassium hydroxide to the round bottom flask, the reaction for 1 hour the liquid from turbid to transparent, add tert-butyllithium, the liquid becomes transparent light yellow. Continue the reaction for 2 hours, the color of the liquid remained unchanged, thin-layer chromatography to detect the progress of the reaction, to be L-Threonine methyl ester reaction is complete to stop the reaction. After cooling to room temperature and filtering, a light yellow powder was obtained. In a round-bottomed flask, add anhydrous dioxane and rotor in a round-bottomed flask, L-threonine methyl ester suspended in dioxane solution, and acylation reaction with fluorenylmethoxycarbonyl azide, thin-layer chromatography to detect the progress of the reaction, to wait for the reaction of O-tert-butyl-L-threonine is complete after the reaction was stopped to obtain the crude O-tert-butyl-L-threonine methyl ester hydrochloride, extracted with ethyl acetate under the condition of pH 9-10 The crude O-tert-butyl-L-threonine methyl ester hydrochloride was extracted with ethyl acetate at pH 9-10 and refined by recrystallization.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

H-Thr(tBu)-OMe HCl Preparation Products And Raw materials

Raw materials

Preparation Products

H-Thr(tBu)-OMe HCl Suppliers

Global Suppliers ( 133)

Supplier	Tel	Email	Country	ProdList	Advantage
Gill polypeptide biopharmaceutical (dalian) co., LTD	021-61263455 13167021076	amy@glschina.com	China	9699	58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD	0838-2809458 13350585791	pharm@biots.cn	China	774	58
Tiantai Yisheng Biochemical Technology Co., Ltd	0576-83869808 18958639818	156697457@qq.com	China	101	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Shanghai Sunway Pharmaceutical Technology Co., Ltd	13761987713	hxzheng@sunwaypharm.cn	China	8663	57

Supplier	Advantage
Gill polypeptide biopharmaceutical (dalian) co., LTD	58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD	58
Tiantai Yisheng Biochemical Technology Co., Ltd	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
Energy Chemical	61
Adamas Reagent, Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Shanghai Sunway Pharmaceutical Technology Co., Ltd	57

View Latest Price from H-Thr(tBu)-OMe HCl manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-13	H-THR(TBU)-OME HCL 71989-43-0		1KG	98%	2000	Shenzhen Nexcon Pharmatechs Ltd.

H-THR(TBU)-OME HCL
71989-43-0
98%
Shenzhen Nexcon Pharmatechs Ltd.

H-Thr(tBu)-OMe HCl Spectrum

H-THR(TBU)-OME HCL(71989-43-0)¹HNMR

71989-43-0 (H-Thr(tBu)-OMe HCl) Related Search:

H-Thr(tBu)-OtBu H-Thr(tBu)-OtBu.AcOH Methyl L-threoninate hydrochloride O-tert-Butyl-L-serine methyl ester hydrochloride L-Threonine hydrochloride

L-Serine hydrochloride L-Serine methyl ester hydrochloride H-Ser(tBu)-OH H-Ser(tBu)-OMe HCl (S)-2-Amino-3-methoxy-propionic acid hydrochloride

H-Thr(tBu)-OH NH2-Et-OtBu HCl (S)-2-Amino-3-ethoxy-propionic acid hydrochloride H-Thr(tBu)-OMe HCl L-Threonine methyl ester

DL-Threonine methyl ester hydrochloride L-Serine methyl ester O-Methyl-L-threonine

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THREONINE(TBU)-OME HCL O-T-BUTYL-L-THREONINE METHYL ESTER HYDROCHLORIDE O-TERT-BUTYL-L-THREONINE METHYL ESTER HYDROCHLORIDE H-L-THR(TBU)-OME HCL H-THR(BUT)-OME HCL Methyl O-(2-Methyl-2-propanyl)-L-threoninate hydrochloride (2S,3R)-Methyl 2-aMino-3-(tert-butoxy)butanoate hydrochloride O-T-Butyl-L-Threonine Methyl Ester Hydrochlorid L-Thr(tBu)-OMe·HCl O-tert-Butyl-L-threonine methyl ester hydrochloride≥ 99% (HPLC) methyl (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoate o-tert-Butyl-L-threoine methyl ester HCl methyl (2S,3R)-2-amino-3-(tert-butoxy)butanoate hydrochloride O-T-Butyl-L-ThreonineMethylEsterHydrochlori H-THR(TBU)-OME HCL USP/EP/BP methyl O-(1,1-dimethylethyl)-L-threoninate hydrochloride L-Threonine, O-(1,1-dimethylethyl)-, methyl ester, hydrochloride (1:1) H-Thr(tBu)-Ome. HC Thr(OtBu)-Ome.HCl H-Thr(tBu)-OMe H-Thr(tBu) Methyl O-(tert-butyl)-L-threoninate hydrochloride H-Thr(tBu)-OMe HCl 71989-43-0 Amino Acid Derivatives Threonine Specialty Synthesis Peptide Synthesis Amino Acid Derivatives Peptide Synthesis Threonine Amino Acids ADVANCED INT.