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5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole

CAS No.
175135-53-2
Chemical Name:
5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole
Synonyms
5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole;5-AMINO-4-CYANO-1-(3-CHLORO-4-FLUOROPHENYL)PYRAZOLE;5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole97%;5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 97%;5-amino-1-(3-chloro-4-fluorophenyl)-4-pyrazolecarbonitrile;5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE;1H-Pyrazole-4-carbonitrile, 5-amino-1-(3-chloro-4-fluorophenyl)-;5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile
CBNumber:
CB3428847
Molecular Formula:
C10H6ClFN4
Molecular Weight:
236.63
MDL Number:
MFCD00052032
MOL File:
175135-53-2.mol
Last updated:2026-09-12 18:52:03

5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole Properties

Melting point 153-154
Boiling point 433.3±45.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
form solid
pka -1.59±0.50(Predicted)
InChI 1S/C10H6ClFN4/c11-8-3-7(1-2-9(8)12)16-10(14)6(4-13)5-15-16/h1-3,5H,14H2
InChIKey CQCMIVONXGCSME-UHFFFAOYSA-N
SMILES Nc1c(cnn1-c2ccc(F)c(Cl)c2)C#N
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  22
WGK Germany  WGK 3
Hazard Note  Irritant
HS Code  2933199090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich JRD0283 5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile Aldrich 175135-53-2 1g $738 2026-04-30 Buy
Usbiological 434821 5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile 175135-53-2 5mg $347 2026-06-03 Buy
Usbiological 434821 5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile 175135-53-2 10mg $489 2026-06-03 Buy
Apolloscientific PC1070C 5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 95% 175135-53-2 50mg $111 2026-06-04 Buy
Apolloscientific PC1070C 5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 95% 175135-53-2 100mg $202 2026-06-04 Buy
Product number Packaging Price Buy
JRD0283 1g $738 Buy
434821 5mg $347 Buy
434821 10mg $489 Buy
PC1070C 50mg $111 Buy
PC1070C 100mg $202 Buy

5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole Chemical Properties,Uses,Production

Uses

5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile is an intermediate in the synthesis of Binucleine 2 (B387153). Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. Highly isoform-specific inhibitor of Drosophila Aurora B kinase.

5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 sales@linyuepharm.com China 5731 55
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Aikon International Limited 17714375163 hywu@aikonchem.com China 9974 58
Yantai Shengkailun Chemical Technology Co., Ltd. 13356901049 mark@sklnchem.cn China 9926 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860 anhua.mao@aladdin-e.com China 43379 58
Alchem Pharmtech,Inc. 8485655694 sales@alchempharmtech.com United States 63645 58
Aladdin Scientific tp@aladdinsci.com United States 54738 58
5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 97% 5-AMINO-4-CYANO-1-(3-CHLORO-4-FLUOROPHENYL)PYRAZOLE 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole97% 5-amino-1-(3-chloro-4-fluorophenyl)-4-pyrazolecarbonitrile 1H-Pyrazole-4-carbonitrile, 5-amino-1-(3-chloro-4-fluorophenyl)- 5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile 5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 175135-53-2 C10H6ClFN4