5-Amino-1-phenylpyrazole
- CAS No.
- 826-85-7
- Chemical Name:
- 5-Amino-1-phenylpyrazole
- Synonyms
- 1-Phenyl-1H-pyrazol-5-amine;BUTTPARK 23\09-46;Aminophenylpyrazole;2-phenylpyrazol-3-amine;5-amino-1-phenyl-pyrazol;5-Amino-1-phenylpyrazole;1-phenylpyrazol-5-ylamine;1-phenyl-1h-pyrazol-5-amin;(2-phenylpyrazol-3-yl)amine;5-Amino-1-phenyl-1H-pyrazole
- CBNumber:
- CB5416480
- Molecular Formula:
- C9H9N3
- Molecular Weight:
- 159.19
- MDL Number:
- MFCD00020734
- MOL File:
- 826-85-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 51°C |
|---|---|
| Boiling point | 123-130 °C(Press: 0.2 Torr) |
| Density | 1.20±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.17±0.10(Predicted) |
| color | White to Light Orange-Yellow |
| InChI | InChI=1S/C9H9N3/c10-9-6-7-11-12(9)8-4-2-1-3-5-8/h1-7H,10H2 |
| InChIKey | ZVNYYNAAEVZNDW-UHFFFAOYSA-N |
| SMILES | N1(C2=CC=CC=C2)C(N)=CC=N1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| RTECS | UQ6108000 | |||||||||
| HS Code | 2933199090 | |||||||||
| NFPA 704 |
|
5-Amino-1-phenylpyrazole price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A0174 | 5-Amino-1-phenylpyrazole >98.0%(GC)(T) | 826-85-7 | 5g | $214 | 2026-04-30 | Buy |
| TCI Chemical | A0174 | 5-Amino-1-phenylpyrazole >98.0%(GC)(T) | 826-85-7 | 25g | $671 | 2026-04-30 | Buy |
| TRC | TRC-A626220-250MG | 5-Amino-1-phenylpyrazole | 826-85-7 | 250mg | $65 | 2026-06-03 | Buy |
| TRC | TRC-A626220-2.5G | 5-Amino-1-phenylpyrazole | 826-85-7 | 2.5g | $109 | 2026-06-03 | Buy |
| TRC | TRC-A626220-1G | 5-Amino-1-phenylpyrazole | 826-85-7 | 1g | $78 | 2026-06-03 | Buy |
5-Amino-1-phenylpyrazole Chemical Properties, Uses, Production
Uses
5-Amino-1-phenylpyrazole is a reagent that is used in the synthesis of sulfaphenazole(S689020) derivatives as inhibitors and tools for comparing active sites of human liver cytochromes P 450 2C subfamily.
Synthesis
16078-71-0
826-85-7
General procedure for the synthesis of 5-amino-1-phenylpyrazole-4-carboxylic acid from ethyl 5-amino-1-phenylpyrazole-4-carboxylate: Step 1: Synthesis of 1-phenyl-1H-pyrazol-5-amine (F1) 5-Amino-4-ethoxy-1-phenylpyrazole (1 eq.) was dissolved in 36% hydrochloric acid solution (30 eq.) and the reaction mixture was stirred under reflux conditions overnight. After completion of the reaction, the mixture was cooled to room temperature, slowly poured into ice water and the pH was adjusted to basic with ammonia. The mixture was extracted with dichloromethane (3 times) and the organic phases were combined. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent to give a light yellow oily product in 94% yield. Mass spectrometry (electrospray positive ionization mode): the theoretical molecular weight of C9H9N3 was 159, and the measured value was 160 (M+H)+.
References
[1] Patent: WO2010/23480, 2010, A1. Location in patent: Page/Page column 48
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 18, p. 4492 - 4498
[3] Journal of the Brazilian Chemical Society, 2018, vol. 29, # 1, p. 159 - 167
[4] Patent: US2858309, 1957,
[5] Helvetica Chimica Acta, 1958, vol. 41, p. 306,309
5-Amino-1-phenylpyrazole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhongshan Jukemei Biotechnology Co., Ltd. | 13642727863 | 1009049100@qq.com | China | 656 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| China Langchem Inc. | 021-58956006,021-58950017 15800617331 | sales@langchem.com | China | 209 | 57 |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
View Latest Price from 5-Amino-1-phenylpyrazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 5-AMINO-1-PHENYLPYRAZOLE
826-85-7
|
$1.00 | 1KG | 98% HPLC | 10 tons/month | Career Henan Chemical Co |
-
- 5-AMINO-1-PHENYLPYRAZOLE
826-85-7
- $1.00
- 98% HPLC
- Career Henan Chemical Co
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