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4'-(Octyloxy)-4-biphenylcarbonitrile

4'-(Octyloxy)-4-biphenylcarbonitrile structure

CAS No.: 52364-73-5

Chemical Name:: 4'-(Octyloxy)-4-biphenylcarbonitrile

Synonyms: 8OCB;M-24;RO-CM-5324;m24(liquidcrystal);OCTYLOXYCYANOBIPHENYL;Octoxybiphenylnitrile;4-cyano-4-octylophenyl;4-octyloxycyanodiphenyl;4-octoxy-4'-cyanobiphenyl;4-Cyano-4’-octoxybiphenyl

CBNumber:: CB3452127

Molecular Formula:: C21H25NO

Molecular Weight:: 307.43

MDL Number:: MFCD00075145

MOL File:: 52364-73-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 06:32:10

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4'-(Octyloxy)-4-biphenylcarbonitrile Properties

Melting point	51-77 °C (lit.)
Boiling point	447.93°C (rough estimate)
Density	1.0505 (rough estimate)
refractive index	1.5614 (estimate)
Flash point	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	liquid crystal (Nematic)
color	White to Almost white
InChI	InChI=1S/C21H25NO/c1-2-3-4-5-6-7-16-23-21-14-12-20(13-15-21)19-10-8-18(17-22)9-11-19/h8-15H,2-7,16H2,1H3
InChIKey	GPGGNNIMKOVSAG-UHFFFAOYSA-N
SMILES	C1(C2=CC=C(OCCCCCCCC)C=C2)=CC=C(C#N)C=C1
FDA UNII	DS9F86ARY6
NIST Chemistry Reference	Octyloxycyanobiphenyl(52364-73-5)
EPA Substance Registry System	[1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)- (52364-73-5)
UNSPSC Code	12352103
NACRES	NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H413

Precautionary statements

P273-P501

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-36/37/38

Safety Statements

26-36

WGK Germany

RTECS

DV1764500

TSCA

TSCA listed

HS Code

29269090

Storage Class

11 - Combustible Solids

Hazard Classifications

Aquatic Chronic 4

NFPA 704

	1
2		0

4'-(Octyloxy)-4-biphenylcarbonitrile price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	338672	4′-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic)	52364-73-5	250mg	$36.1	2023-06-20	Buy
Sigma-Aldrich	338672	4′-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic)	52364-73-5	1g	$114	2023-06-20	Buy
TCI Chemical	C2618	4-Cyano-4'-n-octyloxybiphenyl >98.0%(GC)	52364-73-5	5g	$133	2026-04-30	Buy
TCI Chemical	C2618	4-Cyano-4'-n-octyloxybiphenyl >98.0%(GC)	52364-73-5	25g	$463	2026-04-30	Buy
Usbiological	286285	4'-(Octyloxy)-4-biphenylcarbonitrile Asreported	52364-73-5	5g	$363	2026-06-03	Buy

Product number	Packaging	Price	Buy
338672	250mg	$36.1	Buy
338672	1g	$114	Buy
C2618	5g	$133	Buy
C2618	25g	$463	Buy
286285	5g	$363	Buy

4'-(Octyloxy)-4-biphenylcarbonitrile Chemical Properties,Uses,Production

Chemical Properties

White Crysstalline

Uses

8CB may be used in the preparation of asymmetrical zinc phthalocyanine (aZnPc)-functional photocurable copolymer.

Uses

Intermediates of Liquid Crystals

General Description

4′-octyl-4- biphenylcarbonitrile (8CB) is a low molar mass liquid crystal (LCs), which shows different liquid crystalline phases depending on temperature conditions. Under normal temperature conditions 8CB exists only as bulk smectic-A phase. LCs are responsive to minor changes in temperature, shear, electric (or magnetic) fields, and the structure of solid surfaces with which they are in contact.

Synthesis

111-83-1

19812-93-2

52364-73-5

GENERAL STEPS: 4'-hydroxybiphenyl-4-carbonitrile (20.0 g, 0.1 mol), potassium carbonate (28.0 g, 0.2 mol) and N,N-dimethylformamide (600 mL) were added sequentially in a 1000 mL three-necked flask with magnetic stirring turned on. Subsequently, 1-bromooctane (23.0 g, 0.12 mol) was slowly added dropwise, and the reaction system was warmed to 120 °C and kept for 48 hours. Upon completion of the reaction, the mixture was cooled to room temperature, slowly poured into ice water (1000 mL) and allowed to stand overnight. The precipitated solid product was collected by filtration and purified by recrystallization with ethanol to afford the target compound 4'-octyloxy-[1,1'-biphenyl]-4-carbonitrile.

References

[1] Molecular Crystals and Liquid Crystals, 2008, vol. 480, # 1, p. 287 - 294
[2] Tetrahedron, 2012, vol. 68, # 39, p. 8172 - 8180
[3] Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1995, vol. 268, p. 21 - 44
[4] Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, p. 1192 - 1195
[5] Zhurnal Organicheskoi Khimii, 1984, vol. 20, # 6, p. 1310 - 1314

4'-(Octyloxy)-4-biphenylcarbonitrile synthesis

Synthesis of 4'-(Octyloxy)-4-biphenylcarbonitrile from 4-Bromoanisole

4'-(Octyloxy)-4-biphenylcarbonitrile Preparation Products And Raw materials

Raw materials

[1,1'-Biphenyl]-4-carbonitrile, 4'-iodo- 4'-Cyano[1,1'-biphenyl]-4-yl acetate 4'-Hydroxy-4-biphenylcarbonitrile 4-Cyano-4'-nitrodiphenyl 4'-Aminobiphenyl-4-carbonitrile

4'-methoxy[1,1'-biphenyl]-4-carbonitrile 1-Bromooctane 1-Octanol 4-Bromobenzonitrile 4-Bromoanisole

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Preparation Products

4'-(Octyloxy)-4-biphenylcarbonitrile Suppliers

Global( 167)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Peiling Biological Technology Co., LTD	13127581762 13127581762	peilingchem@sina.com	China	465	58
Nanbu County Chengxin Technology Co., Ltd.	0838-5675166 15883665058	nbcxkj@126.com	China	956	55
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.	0311-89250318 13582355795	master@sjzsdyn.com	China	2776	65
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64

Supplier	Advantage
Shanghai Peiling Biological Technology Co., LTD	58
Nanbu County Chengxin Technology Co., Ltd.	55
INTATRADE GmbH	66
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Beijing HwrkChemical Technology Co., Ltd	55
Energy Chemical	61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.	65
Capot Chemical Co., Ltd	66
Nanjing Chemlin Chemical Co., Ltd	64

View Lastest Price from 4'-(Octyloxy)-4-biphenylcarbonitrile manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-11	4'-(Octyloxy)-4-biphenylcarbonitrile 52364-73-5	$40.00-413.00	25g	0.98	25kg	Shanghai UCHEM Inc.
2026-08-25	4'-(Octyloxy)-4-biphenylcarbonitrile 52364-73-5	$2.00-5.00		99%		ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-03-20	4'-(Octyloxy)-4-biphenylcarbonitrile 52364-73-5		1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd

4'-(Octyloxy)-4-biphenylcarbonitrile
52364-73-5
$40.00-413.00
0.98
Shanghai UCHEM Inc.

4'-(Octyloxy)-4-biphenylcarbonitrile
52364-73-5
$2.00-5.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4'-(Octyloxy)-4-biphenylcarbonitrile
52364-73-5
99%
Hebei Chuanghai Biotechnology Co., Ltd

4'-(Octyloxy)-4-biphenylcarbonitrile Spectrum

4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)MS 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)¹HNMR 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)¹³CNMR 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)IR1 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)Raman

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4'-(Octyloxy)-4-biphenylcarbonitrile

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[1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)- 1’-biphenyl)-4-carbonitrile,4’-(octyloxy)-( 1’-biphenyl]-4-carbonitrile,4’-(octyloxy)-[ 1’-Biphenyl]-4-carbonitrile,4’-(octyloxy)-[1 4-(4-octyloxyphenyl)benzonitrile 4'-(n-Octyloxy)-4-cyanobiphenyl 4'-(Octyloxy)[1,1'-biphenyl]-4-carbonitrile 4'-(Octyloxy)-4-cyanobiphenyl 4-(Octyloxy)-4'-cyanobiphenyl 4’-(octyloxy)-(1,1’-biphenyl)-4-carbonitrile 4-Cyano-4'-(octyloxy)-1,1'-biphenyl 4'-OCTYLOXY-BIPHENYL-4-CARBONITRILE 4-CYANO-4'-OCTYLOXYBIPHENYL 4-CYANO-4'-N-OCTYLOXYBIPHENYL 4-(4'-N-OCTYLOXYPHENYL)-BENZONITRILE 4-(4''-N-OCTYLOXYPHENYL)-BENZONITRILE: 99.5% OCTYLOXYCYANOBIPHENYL 4-octoxybiphenylcarbonitrile 1-(octyloxy)-4-phenylcyclohexa-2,4-diene-1-carbonitrile 4-octoxy-4'-cyanobiphenyl 4'-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic) (Octyloxy)-4-biphenylcarbonitrile 4-(4-octoxyphenyl)benzonitrile 4-Cyano-4’-octoxybiphenyl 4-cyano-4’-octyloxydiphenyl 4-Cyano-4'-octoxybiphenyl 4-octyloxy-4’-cyanobiphenyl 4-octyloxycyanodiphenyl m24(liquidcrystal) p-(Octyloxy)-p'-cyanobiphenyl p-Cyano-p'-(octyloxy)biphenyl RO-CM-5324 4-oetyloxybiphenyl carbonitrile 4-Cyano-4'-n-octyloxybiphenyl> 4-cyano-4-octylophenyl 4'-n-Octyloxy-4-biphenylcarbonitrile Octoxybiphenylnitrile TIANFU CHEM--4'-(Octyloxy)-4-biphenylcarbonitrile 4'-Octyloxy-[1,1'-biphenyl]-4-carbonitrile 4'-(Octyloxy)-4-biphenylcarbonitrile [1,1'-Biphenyl]-4-carbonitrile,4'-(octyloxy)- 4′-(Octyloxy)-4-biphenylcarbonitrile, CAS 52364-73-5 4'-(Octyloxy)-4-biphenylcarbonitrile 8OCB M-24 52364-73-5 CH3CH27OC6H4C6H4CN Biphenyl & Diphenyl ether Liquid Crystals Nematic Organic Electronics and Photonics