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4'-(Octyloxy)-4-biphenylcarbonitrile

4'-(Octyloxy)-4-biphenylcarbonitrile structure

CAS No.: 52364-73-5

Chemical Name:: 4'-(Octyloxy)-4-biphenylcarbonitrile

Synonyms: 8OCB;M-24;RO-CM-5324;m24(liquidcrystal);OCTYLOXYCYANOBIPHENYL;Octoxybiphenylnitrile;4-cyano-4-octylophenyl;4-octyloxycyanodiphenyl;4-octoxy-4'-cyanobiphenyl;4-Cyano-4’-octoxybiphenyl

CBNumber:: CB3452127

Molecular Formula:: C21H25NO

Molecular Weight:: 307.43

MDL Number:: MFCD00075145

MOL File:: 52364-73-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:44

Product description	Number	Pack Size	Price
4′-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic)	338672	250mg	$36.1
4′-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic)	338672	1g	$114
4-Cyano-4'-n-octyloxybiphenyl >98.0%(GC)	C2618	5g	$133
4-Cyano-4'-n-octyloxybiphenyl >98.0%(GC)	C2618	25g	$463
4''-(Octyloxy)-4-biphenylcarbonitrile	O293265	5g	$130
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4'-(Octyloxy)-4-biphenylcarbonitrile Properties

Melting point	51-77 °C (lit.)
Boiling point	447.93°C (rough estimate)
Density	1.0505 (rough estimate)
refractive index	1.5614 (estimate)
Flash point	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	liquid crystal (Nematic)
color	White to Almost white
InChI	InChI=1S/C21H25NO/c1-2-3-4-5-6-7-16-23-21-14-12-20(13-15-21)19-10-8-18(17-22)9-11-19/h8-15H,2-7,16H2,1H3
InChIKey	GPGGNNIMKOVSAG-UHFFFAOYSA-N
SMILES	C1(C2=CC=C(OCCCCCCCC)C=C2)=CC=C(C#N)C=C1
FDA UNII	DS9F86ARY6
NIST Chemistry Reference	Octyloxycyanobiphenyl(52364-73-5)
EPA Substance Registry System	[1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)- (52364-73-5)
UNSPSC Code	12352103
NACRES	NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H413

Precautionary statements

P273-P501

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-36/37/38

Safety Statements

26-36

WGK Germany

RTECS

DV1764500

TSCA

TSCA listed

HS Code

29269090

Storage Class

11 - Combustible Solids

Hazard Classifications

Aquatic Chronic 4

NFPA 704

	1
2		0

4'-(Octyloxy)-4-biphenylcarbonitrile price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	338672	4′-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic)	52364-73-5	250mg	$36.1	2023-06-20	Buy
Sigma-Aldrich	338672	4′-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic)	52364-73-5	1g	$114	2023-06-20	Buy
TCI Chemical	C2618	4-Cyano-4'-n-octyloxybiphenyl >98.0%(GC)	52364-73-5	5g	$133	2026-03-19	Buy
TCI Chemical	C2618	4-Cyano-4'-n-octyloxybiphenyl >98.0%(GC)	52364-73-5	25g	$463	2026-03-19	Buy
TRC	O293265	4''-(Octyloxy)-4-biphenylcarbonitrile	52364-73-5	5g	$130	2021-12-16	Buy

Product number	Packaging	Price	Buy
338672	250mg	$36.1	Buy
338672	1g	$114	Buy
C2618	5g	$133	Buy
C2618	25g	$463	Buy
O293265	5g	$130	Buy

4'-(Octyloxy)-4-biphenylcarbonitrile Chemical Properties,Uses,Production

Chemical Properties

White Crysstalline

Uses

8CB may be used in the preparation of asymmetrical zinc phthalocyanine (aZnPc)-functional photocurable copolymer.

Uses

Intermediates of Liquid Crystals

General Description

4′-octyl-4- biphenylcarbonitrile (8CB) is a low molar mass liquid crystal (LCs), which shows different liquid crystalline phases depending on temperature conditions. Under normal temperature conditions 8CB exists only as bulk smectic-A phase. LCs are responsive to minor changes in temperature, shear, electric (or magnetic) fields, and the structure of solid surfaces with which they are in contact.

Synthesis

111-83-1

19812-93-2

52364-73-5

GENERAL STEPS: 4'-hydroxybiphenyl-4-carbonitrile (20.0 g, 0.1 mol), potassium carbonate (28.0 g, 0.2 mol) and N,N-dimethylformamide (600 mL) were added sequentially in a 1000 mL three-necked flask with magnetic stirring turned on. Subsequently, 1-bromooctane (23.0 g, 0.12 mol) was slowly added dropwise, and the reaction system was warmed to 120 °C and kept for 48 hours. Upon completion of the reaction, the mixture was cooled to room temperature, slowly poured into ice water (1000 mL) and allowed to stand overnight. The precipitated solid product was collected by filtration and purified by recrystallization with ethanol to afford the target compound 4'-octyloxy-[1,1'-biphenyl]-4-carbonitrile.

References

[1] Molecular Crystals and Liquid Crystals, 2008, vol. 480, # 1, p. 287 - 294
[2] Tetrahedron, 2012, vol. 68, # 39, p. 8172 - 8180
[3] Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1995, vol. 268, p. 21 - 44
[4] Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, p. 1192 - 1195
[5] Zhurnal Organicheskoi Khimii, 1984, vol. 20, # 6, p. 1310 - 1314

4'-(Octyloxy)-4-biphenylcarbonitrile synthesis

Synthesis of 4'-(Octyloxy)-4-biphenylcarbonitrile from 4-Bromoanisole

4'-(Octyloxy)-4-biphenylcarbonitrile Preparation Products And Raw materials

Raw materials

[1,1'-Biphenyl]-4-carbonitrile, 4'-iodo- 4'-CYANO[1,1'-BIPHENYL]-4-YL ACETATE 4'-Hydroxy-4-biphenylcarbonitrile 4-CYANO-4'-NITRODIPHENYL 4'-Aminobiphenyl-4-carbonitrile

4'-methoxy[1,1'-biphenyl]-4-carbonitrile 1-Bromooctane 1-Octanol 4-Bromobenzonitrile 4-Bromoanisole

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Preparation Products

4'-(Octyloxy)-4-biphenylcarbonitrile Suppliers

Global( 166)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8792	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13815	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21591	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29820	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2949	58
Beijing Yanhua Jilian Opto-Electronic Technology Co., Ltd.	(+86)13146479469		CHINA	315	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Shanghai UCHEM Inc.	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Beijing Yanhua Jilian Opto-Electronic Technology Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 4'-(Octyloxy)-4-biphenylcarbonitrile manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-28	4'-(Octyloxy)-4-biphenylcarbonitrile 52364-73-5	US $40.00-413.00 / g	25g	0.98	25kg	Shanghai UCHEM Inc.
2026-04-17	4'-(Octyloxy)-4-biphenylcarbonitrile 52364-73-5	US $2.00-5.00 / KG	0.1KG	99%	g-kg-tons	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-03-20	4'-(Octyloxy)-4-biphenylcarbonitrile 52364-73-5	US $0.00-0.00 / KG	1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd

4'-(Octyloxy)-4-biphenylcarbonitrile
52364-73-5
US $40.00-413.00 / g
0.98
Shanghai UCHEM Inc.

4'-(Octyloxy)-4-biphenylcarbonitrile
52364-73-5
US $2.00-5.00 / KG
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4'-(Octyloxy)-4-biphenylcarbonitrile
52364-73-5
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4'-(Octyloxy)-4-biphenylcarbonitrile Spectrum

4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)MS 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)¹HNMR 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)¹³CNMR 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)IR1 4'-(Octyloxy)-4-biphenylcarbonitrile(52364-73-5)Raman

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4'-(Octyloxy)-4-biphenylcarbonitrile

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[1,1'-Biphenyl]-4-carbonitrile, 4'-(octyloxy)- 1’-biphenyl)-4-carbonitrile,4’-(octyloxy)-( 1’-biphenyl]-4-carbonitrile,4’-(octyloxy)-[ 1’-Biphenyl]-4-carbonitrile,4’-(octyloxy)-[1 4-(4-octyloxyphenyl)benzonitrile 4'-(n-Octyloxy)-4-cyanobiphenyl 4'-(Octyloxy)[1,1'-biphenyl]-4-carbonitrile 4'-(Octyloxy)-4-cyanobiphenyl 4-(Octyloxy)-4'-cyanobiphenyl 4’-(octyloxy)-(1,1’-biphenyl)-4-carbonitrile 4-Cyano-4'-(octyloxy)-1,1'-biphenyl 4'-OCTYLOXY-BIPHENYL-4-CARBONITRILE 4-CYANO-4'-OCTYLOXYBIPHENYL 4-CYANO-4'-N-OCTYLOXYBIPHENYL M-24 8OCB 4-(4'-N-OCTYLOXYPHENYL)-BENZONITRILE 4-(4''-N-OCTYLOXYPHENYL)-BENZONITRILE: 99.5% OCTYLOXYCYANOBIPHENYL 4-octoxybiphenylcarbonitrile 1-(octyloxy)-4-phenylcyclohexa-2,4-diene-1-carbonitrile 4-octoxy-4'-cyanobiphenyl 4'-(Octyloxy)-4-biphenylcarbonitrile liquid crystal (nematic) (Octyloxy)-4-biphenylcarbonitrile 4-(4-octoxyphenyl)benzonitrile 4-Cyano-4’-octoxybiphenyl 4-cyano-4’-octyloxydiphenyl 4-Cyano-4'-octoxybiphenyl 4-octyloxy-4’-cyanobiphenyl 4-octyloxycyanodiphenyl m24(liquidcrystal) p-(Octyloxy)-p'-cyanobiphenyl p-Cyano-p'-(octyloxy)biphenyl RO-CM-5324 4-oetyloxybiphenyl carbonitrile 4-Cyano-4'-n-octyloxybiphenyl> 4-cyano-4-octylophenyl 4'-n-Octyloxy-4-biphenylcarbonitrile Octoxybiphenylnitrile TIANFU CHEM--4'-(Octyloxy)-4-biphenylcarbonitrile 4'-Octyloxy-[1,1'-biphenyl]-4-carbonitrile 4'-(Octyloxy)-4-biphenylcarbonitrile [1,1'-Biphenyl]-4-carbonitrile,4'-(octyloxy)- 4′-(Octyloxy)-4-biphenylcarbonitrile, CAS 52364-73-5 4'-(Octyloxy)-4-biphenylcarbonitrile 52364-73-5 CH3CH27OC6H4C6H4CN Biphenyl & Diphenyl ether Liquid Crystals Nematic Organic Electronics and Photonics