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RIPK2 inhibitor 1

CAS No.
1290490-78-6
Chemical Name:
RIPK2 inhibitor 1
Synonyms
RIPK2-IN-3;RIPK2 inhibitor;RIPK2 inhibitor 1;3-Benzamido-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide;Benzamide, 3-(benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]-
CBNumber:
CB34668443
Molecular Formula:
C25H22N4O2
Molecular Weight:
410.47
MDL Number:
MOL File:
1290490-78-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:32:44

RIPK2 inhibitor 1 Properties

storage temp. 2-8°C
solubility Soluble to 100 mM in DMSO
form powder
color white to very dark gray
InChI 1S/C25H22N4O2/c1-17-11-12-20(16-22(17)28-24(30)18-7-4-3-5-8-18)25(31)27-21-10-6-9-19(15-21)23-26-13-14-29(23)2/h3-16H,1-2H3,(H,27,31)(H,28,30)
InChIKey OIIYBZHRYXJCHR-UHFFFAOYSA-N
SMILES CC1=CC=C(C(NC2=CC(C3=NC=CN3C)=CC=C2)=O)C=C1NC(C4=CC=CC=C4)=O
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H303-H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P312-P264-P280-P302+P352-P321-P332+P313-P362
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

RIPK2 inhibitor 1 price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2554 RIPK2 inhibitor 1 ≥98% (HPLC) 1290490-78-6 5mg $78.28 2026-04-30 Buy
Sigma-Aldrich SML2554 RIPK2 inhibitor 1 ≥98% (HPLC) 1290490-78-6 25mg $464 2026-04-30 Buy
Biosynth QBC49078 3-Benzamido-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide 1290490-78-6 50mg $637 2026-06-04 Buy
Biosynth QBC49078 3-Benzamido-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide 1290490-78-6 0.5g $2006 2026-06-04 Buy
aablocks AA0200P2 3-benzamido-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide >98%(HPLC) 1290490-78-6 5mg $450 2026-06-01 Buy
Product number Packaging Price Buy
SML2554 5mg $78.28 Buy
SML2554 25mg $464 Buy
QBC49078 50mg $637 Buy
QBC49078 0.5g $2006 Buy
AA0200P2 5mg $450 Buy

RIPK2 inhibitor 1 Chemical Properties, Uses, Production

Uses

RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor. RIPK2-IN-3 inhibits recombinant truncated RIPK2 with an IC50 of 6.39 μM. RIPK2-IN-3 can be used for research of inflammation and cancer[1].

Biological Activity

RIPK2 inhibitor 1 is a potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) th at potently inhibit NFKB activity and the proliferation of cancer cell lines. RIPK2 inhibitor 1 inhibits intestinal and lung inflammation in rodent models.

storage

Store at -20°C

References

[1] Shairaz BAKSH, et al. Ripk2 inhibitors. WO2019161495.

RIPK2 inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

RIPK2 inhibitor 1 Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD 86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6288 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 5000 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
ChemOrigin Pharm 15026428026 19002516454 ChemOrigin@126.com China 1585 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58

RIPK2 inhibitor 1 Spectrum

RIPK2 inhibitor 1 Benzamide, 3-(benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]- RIPK2-IN-3 3-Benzamido-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide RIPK2 inhibitor 1290490-78-6