Foliglurax hydrochloride
- CAS No.
- 2133294-96-7
- Chemical Name:
- Foliglurax hydrochloride
- Synonyms
- PXT002331;PXT 002331;Foliglurax hydrochloride;Foliglurax monohydrochloride;PXT002331 (monohydrochloride)
- CBNumber:
- CB34844780
- Molecular Formula:
- C23H24ClN3O3S
- Molecular Weight:
- 457.97
- MDL Number:
- MOL File:
- 2133294-96-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO : 5 mg/mL (10.92 mM) |
| form | Solid |
| color | Light yellow to yellow |
| FDA UNII | 27P8U380HS |
Foliglurax hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0068027 | Foliglurax (monohydrochloride) 98.57% | 2133294-96-7 | 5mg | $487 | 2026-06-04 | Buy |
| ChemScene | CS-0068027 | Foliglurax (monohydrochloride) 98.57% | 2133294-96-7 | 10mg | $812 | 2026-06-04 | Buy |
| ChemScene | CS-0068027 | Foliglurax (monohydrochloride) 98.57% | 2133294-96-7 | 25mg | $1625 | 2026-06-04 | Buy |
| ChemScene | CS-0068027 | Foliglurax (monohydrochloride) 98.57% | 2133294-96-7 | 50mg | $2275 | 2026-06-04 | Buy |
| ChemScene | CS-0068027 | Foliglurax (monohydrochloride) 98.57% | 2133294-96-7 | 100mg | $3575 | 2026-06-04 | Buy |
Foliglurax hydrochloride Chemical Properties, Uses, Production
Uses
Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM[1]. Antiparkinsonian effect[1].
IC 50
mGlu4: 79 nM (EC50)
References
[1] Charvin D, et al. Discovery, Structure-Activity Relationship, and Antiparkinsonian Effect of a Potent and Brain-Penetrant Chemical Series of Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4. J Med Chem. 2017 Oct 26;60(20):8515-8537. DOI:10.1021/acs.jmedchem.7b00991
[2] Volpi C, et al. Opportunities and challenges in drug discovery targeting metabotropic glutamate receptor 4. Expert Opin Drug Discov. 2018 May;13(5):411-423. DOI:10.1080/17460441.2018.1443076
Foliglurax hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Foliglurax hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Anhui JYHX CO., LTD. | 055167162561 13295518198 | wangyanan@ahjyhx.com | China | 2044 | 58 |
| Shaanxi Didu Pharmaceutical Co., Ltd. | 029-81124775 17791530730 | 1079@dideu.com | China | 10000 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
View Latest Price from Foliglurax hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | Foliglurax monohydrochloride
2133294-96-7
|
$2170.00-4380.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-07-15 | Foliglurax monohydrochloride
2133294-96-7
|
$2170.00-4380.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-06-30 | Foliglurax monohydrochloride
2133294-96-7
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd |
-
- Foliglurax monohydrochloride
2133294-96-7
- $2170.00-4380.00
- TargetMol Chemicals Inc.
-
- Foliglurax monohydrochloride
2133294-96-7
- $2170.00-4380.00
- TargetMol Chemicals Inc.
-
- Foliglurax monohydrochloride
2133294-96-7
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
