Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Mizagliflozin

Mizagliflozin

Mizagliflozin Structure
Mizagliflozin structure
CAS No.
666843-10-3
Chemical Name:
Mizagliflozin
Synonyms
KGA3235;KGA 3235;KGA-3235;GSK1614235;GSK-1614235;GSK 1614235;Mizagliflozin;DSP-3235 free base;KGA-3235 free base;GSK-1614235 free base
CBNumber:
CB34919871
Molecular Formula:
C28H44N4O8
Molecular Weight:
564.68
MDL Number:
MOL File:
666843-10-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-31 15:04:38
Request For Quotation

Mizagliflozin Properties

Boiling point 837.0±65.0 °C(Predicted)
Density 1.274±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility Methanol: 250 mg/mL (442.74 mM); DMSO: 100 mg/mL (177.09 mM)
form Solid
pka 12.65±0.70(Predicted)
color Off-white to light yellow
FDA UNII 1X96A704XV

Mizagliflozin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth RBB84310 Mizagliflozin 666843-10-3 25mg $1177.25 2026-06-05 Buy
Biosynth RBB84310 Mizagliflozin 666843-10-3 50mg $1637.5 2026-06-05 Buy
ChemScene CS-0016832 Mizagliflozin 99.20% 666843-10-3 5mg $195 2026-06-04 Buy
ChemScene CS-0016832 Mizagliflozin 99.20% 666843-10-3 10mg $314 2026-06-04 Buy
ChemScene CS-0016832 Mizagliflozin 99.20% 666843-10-3 25mg $628 2026-06-04 Buy
Product number Packaging Price Buy
RBB84310 25mg $1177.25 Buy
RBB84310 50mg $1637.5 Buy
CS-0016832 5mg $195 Buy
CS-0016832 10mg $314 Buy
CS-0016832 25mg $628 Buy

Mizagliflozin Chemical Properties,Uses,Production

Uses

Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation[1].

in vivo

Mizagliflozin (DSP-3235 free base) (3-30 mg/kg; oral) exerts a laxative effect[1].
Mizagliflozin administrated intravenously (0.3 mg/kg) and orally (3 mg/kg) declined with a short half-life (0.23 and 1.14 h, respectively)[2]

Animal Model:Male Wistar rats (rat model of low-fiber-diet-induced constipation)[1]
Dosage:3, 10, 30 mg/kg
Administration:Oral
Result:Increased fecal wet weight in a rat model of low-fiber-diet-induced constipation.

IC 50

SGLT1

References

[1] Inoue T, et al. Mizagliflozin, a novel selective SGLT1 inhibitor, exhibits potential in the amelioration of chronic constipation. Eur J Pharmacol. 2017 Jul 5;806:25-31. DOI:10.1016/j.ejphar.2017.04.010
[2] Ohno H, et al. Absorption, disposition, metabolism and excretion of [14C]mizagliflozin, a novel selective SGLT1 inhibitor, in rats. Xenobiotica. 2019 Apr;49(4):463-473. DOI:10.1080/00498254.2018.1449269

Mizagliflozin Preparation Products And Raw materials

Raw materials

Preparation Products

Mizagliflozin Suppliers

Global( 46)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Twochem Co.Ltd 021-021-58111628 15800915896 sales@twochem.com China 303 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6039 18920764717 sales@heowns.com China 24636 60
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Changzhou Chenhong Biotechnology Co., Ltd. +86-0519-85788828 +86-13775037613 sales@chemrenpharm.com China 4058 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
Twochem Co.Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Tianjin heowns Biochemical Technology Co., Ltd. 60
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
Changzhou Chenhong Biotechnology Co., Ltd. 58

View Lastest Price from Mizagliflozin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mizagliflozin pictures 2026-07-31 Mizagliflozin
666843-10-3
 $61.00-147.00 99.60% 10g TargetMol Chemicals Inc.
  • Mizagliflozin pictures
  • Mizagliflozin
    666843-10-3
  • $61.00-147.00
  • 99.60%
  • TargetMol Chemicals Inc.

Mizagliflozin Spectrum

Mizagliflozin(666843-10-3)1HNMR

666843-10-3(Mizagliflozin)Related Search:

KGA2727 Mizagliflozin 4-[[4-[(1E)-4-(2,9-Diazaspiro[5.5]undec-2-yl)-1-buten-1-yl]-2-methylphenyl]methyl]-5-(1-methylethyl)-1H-pyrazol-3-yl β-D-glucopyranoside Canagliflozin Ipragliflozin
Phlorizin

1of2

Mizagliflozin DSP-3235 free base GSK-1614235 free base KGA-3235 free base Propanamide, 3-[[3-[4-[[3-(β-D-glucopyranosyloxy)-5-(1-methylethyl)-1H-pyrazol-4-yl]methyl]-3-methylphenoxy]propyl]amino]-2,2-dimethyl- GSK1614235,Chronic,KGA 3235,DSP-3235,selective,Sodium-dependent glucose cotransporters,KGA-3235,constipation,Mizagliflozin,antidiabetic,disorder,SGLT,gastrointestinal,DSP 3235,inhibit,GSK 1614235,Inhibitor,KGA3235,GSK-1614235,DSP3235 Mizagliflozin (KWA 0711) GSK 1614235 GSK1614235 GSK-1614235 KGA 3235 KGA3235 KGA-3235 3-((3-(4-((5-Isopropyl-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1H-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethylpropanamide Mizagliflozin, 10 mM in DMSO 666843-10-3 C28H44N4O8