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Mizagliflozin

Mizagliflozin Structure
Mizagliflozin structure
CAS No.
666843-10-3
Chemical Name:
Mizagliflozin
Synonyms
KGA3235;KGA 3235;KGA-3235;GSK1614235;GSK-1614235;GSK 1614235;Mizagliflozin;DSP-3235 free base;KGA-3235 free base;GSK-1614235 free base
CBNumber:
CB34919871
Molecular Formula:
C28H44N4O8
Molecular Weight:
564.68
MDL Number:
MOL File:
666843-10-3.mol
Last updated:2026-03-06 19:22:19
Product description Number Pack Size Price
Mizagliflozin 99.64% CS-0016832 5mg $480
Mizagliflozin 99.64% CS-0016832 10mg $800
Mizagliflozin 99.64% CS-0016832 25mg $1600
Mizagliflozin 99.64% CS-0016832 50mg $2500
Mizagliflozin 99.64% CS-0016832 100mg $4000
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Mizagliflozin Properties

Boiling point 837.0±65.0 °C(Predicted)
Density 1.274±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility Methanol: 250 mg/mL (442.74 mM); DMSO: 100 mg/mL (177.09 mM)
form Solid
pka 12.65±0.70(Predicted)
color Off-white to light yellow
FDA UNII 1X96A704XV

Mizagliflozin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0016832 Mizagliflozin 99.64% 666843-10-3 5mg $480 2021-12-16 Buy
ChemScene CS-0016832 Mizagliflozin 99.64% 666843-10-3 10mg $800 2021-12-16 Buy
ChemScene CS-0016832 Mizagliflozin 99.64% 666843-10-3 25mg $1600 2021-12-16 Buy
ChemScene CS-0016832 Mizagliflozin 99.64% 666843-10-3 50mg $2500 2021-12-16 Buy
ChemScene CS-0016832 Mizagliflozin 99.64% 666843-10-3 100mg $4000 2021-12-16 Buy
Product number Packaging Price Buy
CS-0016832 5mg $480 Buy
CS-0016832 10mg $800 Buy
CS-0016832 25mg $1600 Buy
CS-0016832 50mg $2500 Buy
CS-0016832 100mg $4000 Buy

Mizagliflozin Chemical Properties,Uses,Production

Uses

Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation[1].

in vivo

Mizagliflozin (DSP-3235 free base) (3-30 mg/kg; oral) exerts a laxative effect[1].
Mizagliflozin administrated intravenously (0.3 mg/kg) and orally (3 mg/kg) declined with a short half-life (0.23 and 1.14 h, respectively)[2]

Animal Model:Male Wistar rats (rat model of low-fiber-diet-induced constipation)[1]
Dosage:3, 10, 30 mg/kg
Administration:Oral
Result:Increased fecal wet weight in a rat model of low-fiber-diet-induced constipation.

IC 50

SGLT1

References

[1] Inoue T, et al. Mizagliflozin, a novel selective SGLT1 inhibitor, exhibits potential in the amelioration of chronic constipation. Eur J Pharmacol. 2017 Jul 5;806:25-31. DOI:10.1016/j.ejphar.2017.04.010
[2] Ohno H, et al. Absorption, disposition, metabolism and excretion of [14C]mizagliflozin, a novel selective SGLT1 inhibitor, in rats. Xenobiotica. 2019 Apr;49(4):463-473. DOI:10.1080/00498254.2018.1449269

Mizagliflozin Preparation Products And Raw materials

Raw materials

Preparation Products

Mizagliflozin Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32469 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2538 55
Twochem Co.Ltd 021-021-58111628 15800915896 sales@twochem.com China 304 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6039 18920764717 sales@heowns.com China 23933 60
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Shanghai Beckham Medical Technology Co., Ltd 55
Twochem Co.Ltd 55
ShangHai Biochempartner Co.,Ltd 62
Tianjin heowns Biochemical Technology Co., Ltd. 60

View Lastest Price from Mizagliflozin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mizagliflozin pictures 2026-03-06 Mizagliflozin
666843-10-3
 US $61.00-147.00 / mg 99.60% 10g TargetMol Chemicals Inc.
  • Mizagliflozin pictures
  • Mizagliflozin
    666843-10-3
  • US $61.00-147.00 / mg
  • 99.60%
  • TargetMol Chemicals Inc.

Mizagliflozin Spectrum

Mizagliflozin(666843-10-3)1HNMR
Mizagliflozin DSP-3235 free base GSK-1614235 free base KGA-3235 free base Propanamide, 3-[[3-[4-[[3-(β-D-glucopyranosyloxy)-5-(1-methylethyl)-1H-pyrazol-4-yl]methyl]-3-methylphenoxy]propyl]amino]-2,2-dimethyl- GSK1614235,Chronic,KGA 3235,DSP-3235,selective,Sodium-dependent glucose cotransporters,KGA-3235,constipation,Mizagliflozin,antidiabetic,disorder,SGLT,gastrointestinal,DSP 3235,inhibit,GSK 1614235,Inhibitor,KGA3235,GSK-1614235,DSP3235 Mizagliflozin (KWA 0711) GSK 1614235 GSK1614235 GSK-1614235 KGA 3235 KGA3235 KGA-3235 3-((3-(4-((5-Isopropyl-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1H-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethylpropanamide Mizagliflozin, 10 mM in DMSO 666843-10-3 C28H44N4O8