ChemicalBook >> CAS DataBase List >>2,4,6-Trichloro-5-methylpyrimidine
2,4,6-Trichloro-5-methylpyrimidine
- CAS No.
- 1780-36-5
- Chemical Name:
- 2,4,6-Trichloro-5-methylpyrimidine
- Synonyms
- 2,4,6-Trichoro-5-MethylpyriMidine;2,4,6-TRICHLORO-5-METHYLPYRIMIDINE;5-Methyl-2,4,6-trichloropyrimidine;Pyrimidine, 2,4,6-trichloro-5-methyl-;5-Methyl-2,4,6-trichloropyrimidine 98%;2,4,6-TRICHLORO-5-METHYLPYRIMIDINE, 98+%;2,4,6-
Trichloro- 5- MethylpyriMidine;2,4,6-Trichloro-5-methylpyrimidine ISO 9001：2015 REACH
- CBNumber:
- CB3496309
- Molecular Formula:
- C5H3Cl3N2
- Molecular Weight:
- 197.45
- MDL Number:
- MFCD00233525
- MOL File:
- 1780-36-5.mol
Last updated:2026-01-13 11:18:45
| Product description | Number | Pack Size | Price |
| 2,4,6-Trichloro-5-methylpyrimidine 97% | 679054 | 1g | $112 |
| 2,4,6-Trichloro-5-methylpyrimidine | T774393 | 1g | $65 |
| 2,4,6-Trichloro-5-methylpyrimidine | NT67801 | 10g | $72.5 |
| 5-Methyl-2,4,6-trichloropyrimidine 97% | 3H32-5-3M | 5G | $85 |
| 2,4,6-Trichloro-5-methylpyrimidine 95+% | 073214 | 1g | $35 |
| More product size | |||
| Melting point | 65-69 °C |
|---|---|
| Boiling point | 132-136 °C(Press: 23-25 Torr) |
| Density | 1.542±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | solid |
| pka | -6.75±0.39(Predicted) |
| color | Off-white |
| InChI | 1S/C5H3Cl3N2/c1-2-3(6)9-5(8)10-4(2)7/h1H3 |
| InChIKey | VTSWSQGDJQFXHB-UHFFFAOYSA-N |
| SMILES | Cc1c(Cl)nc(Cl)nc1Cl |
| CAS DataBase Reference | 1780-36-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 22-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3261 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | Ⅱ | |||||||||
| HS Code | 29335990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Corr. 1B |
|||||||||
| NFPA 704 |
|
2,4,6-Trichloro-5-methylpyrimidine price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 679054 | 2,4,6-Trichloro-5-methylpyrimidine 97% | 1780-36-5 | 1g | $112 | 2023-06-20 | Buy |
| TRC | T774393 | 2,4,6-Trichloro-5-methylpyrimidine | 1780-36-5 | 1g | $65 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NT67801 | 2,4,6-Trichloro-5-methylpyrimidine | 1780-36-5 | 10g | $72.5 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3H32-5-3M | 5-Methyl-2,4,6-trichloropyrimidine 97% | 1780-36-5 | 5G | $85 | 2021-12-16 | Buy |
| Matrix Scientific | 073214 | 2,4,6-Trichloro-5-methylpyrimidine 95+% | 1780-36-5 | 1g | $35 | 2021-12-16 | Buy |
2,4,6-Trichloro-5-methylpyrimidine Chemical Properties,Uses,Production
Synthesis
2565-47-1
1780-36-5
1. 450 mL (2.94 mol) of phosphorus trichloride was added to a 2-liter flask and 49.3 mL (0.39 mol) of N,N-dimethylaniline was added slowly while cooling and stirring. 2. 142 g (1 mol) of 1-methylpyrimidine-2,4,6(1H,3H,5H)-trione was added in a batch over 20 min and the reaction was exothermic. 3. the reaction mixture was heated to reflux and held for 5 hours until gas escape ceased. 4. the reaction suspension is slowly poured into water at a controlled temperature of 25°C to 30°C 5. Filter the aqueous suspension by suction and dissolve the filtrate in 250 mL of dichloromethane. 6. Filter the solution until clear and extract twice with 250 mL of ice water. 7. The organic phase was dried and concentrated by evaporation to give a crystalline residue. 8. the residue was dried under vacuum to give 126.7 g of 5-methyl-2,4,6-trichloropyrimidine crystals with a melting point of 67°C-68°C and a yield of 64.2% of the theoretical value.
References
[1] Patent: US4741760, 1988, A
2,4,6-Trichloro-5-methylpyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 168)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 2,4,6-Trichloro-5-methylpyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 2,4,6-Trichloro-5-methylpyrimidine
1780-36-5
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-06-27 | 2,4,6-Trichloro-5-methylpyrimidine
1780-36-5
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-05-23 | 2,4,6-Trichloro-5-methylpyrimidine
1780-36-5
|
US $100.00-50.00 / kg | 1kg | 99% | 20 tons | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- 2,4,6-Trichloro-5-methylpyrimidine
1780-36-5
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2,4,6-Trichloro-5-methylpyrimidine
1780-36-5
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2,4,6-Trichloro-5-methylpyrimidine
1780-36-5
- US $100.00-50.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
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1of4
5-Methyl-2,4,6-trichloropyrimidine 98%
2,4,6-Trichoro-5-MethylpyriMidine
2,4,6-Trichloro-5-MethylpyriMidine
2,4,6-TRICHLORO-5-METHYLPYRIMIDINE
Pyrimidine, 2,4,6-trichloro-5-methyl-
5-Methyl-2,4,6-trichloropyrimidine
2,4,6-TRICHLORO-5-METHYLPYRIMIDINE, 98+%
2,4,6-Trichloro-5-methylpyrimidine ISO 9001：2015 REACH
1780-36-5
C5H3Cl3N2
C5H3N2Cl3
Building Blocks
Halogenated Heterocycles
Heterocyclic Building Blocks
Pyrimidines
PyrimidinesHeterocyclic Building Blocks
Heterocycle-Pyrimidine series
APIs & Intermediate
Pyrimidine
Pyridines, Pyrimidines, Purines and Pteredines
pharmacetical
