ChemicalBook >> CAS DataBase List >>5-CHLORO-2-FLUOROPHENYLBORONIC ACID
5-CHLORO-2-FLUOROPHENYLBORONIC ACID
- CAS No.
- 352535-83-2
- Chemical Name:
- 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
- Synonyms
- 57842;AKOS BRN-0727;5-chloro-2-fluorophenylboric acid;5-Chloro-2-fluorophenylbornic acid;(5-chloro-2-fluorophenyl)boronicaci;5-CHLORO-2-FLUOROPHENYLBORONIC ACID;5-CHLORO-2-FLUOROBENZENEBORONIC ACID;5-Chloro-2-fluorobenzeneboronicacid97%;B-(5-Chloro-2-fluorophenyl)boronic acid;5-Chloro-2-fluorobenzeneboronic acid 97%
- CBNumber:
- CB3663716
- Molecular Formula:
- C6H5BClFO2
- Molecular Weight:
- 174.37
- MDL Number:
- MFCD05664225
- MOL File:
- 352535-83-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 03:56:05
| Melting point | 122-127 °C (lit.) |
|---|---|
| Boiling point | 310.8±52.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 7.35±0.58(Predicted) |
| color | White to Almost white |
| InChI | 1S/C6H5BClFO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,10-11H |
| InChIKey | GGTUVWGMCFXUAS-UHFFFAOYSA-N |
| SMILES | OB(O)c1cc(Cl)ccc1F |
| CAS DataBase Reference | 352535-83-2(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37-60 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
5-CHLORO-2-FLUOROPHENYLBORONIC ACID price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2645 | 5-Chloro-2-fluorophenylboronic Acid (contains varying amounts of Anhydride) | 352535-83-2 | 5g | $66 | 2026-04-30 | Buy |
| AstaTech | 57842 | 5-CHLORO-2-FLUOROPHENYLBORONIC ACID 97% | 352535-83-2 | 25G | $85 | 2026-04-30 | Buy |
| AstaTech | 57842 | 5-CHLORO-2-FLUOROPHENYLBORONIC ACID 97% | 352535-83-2 | 100G | $246 | 2026-04-30 | Buy |
| Apolloscientific | PC1635 | 5-Chloro-2-fluorobenzeneboronic acid 97% | 352535-83-2 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC1635 | 5-Chloro-2-fluorobenzeneboronic acid 97% | 352535-83-2 | 5g | $85 | 2026-06-04 | Buy |
5-CHLORO-2-FLUOROPHENYLBORONIC ACID Chemical Properties,Uses,Production
Uses
suzuki reaction
Uses
Reactant involved in:
- Suzuki cross-coupling reactions
- Synthesis of biaryl amides with muscarinic acetylcholine receptor subtype M1 agonistic activity
- Synthesis of kinesin spindle protein inhibitors
- GABA α2/3 agonist preparation
Synthesis
To a solution of 2-bromo-4-chloro-1-fluorobenzene (5 g, 0.0238 mol) in anhydrous ether (30 ) at -70C under nitrogen atmosphere was added a 2M solution of n-BuLi in hexane (13 mL, 0.0262 mol). mL) in anhydrous ether (30 ) was added to a 2 M solution of n-BuLi in hexane (13 mL, 0.0262 mol). The solution was stirred at the same temperature for 30 min and then triisopropyl borate (4.93 g,0.0262 mol) was added dropwise to the solution. The white slurry formed was stirred at -70 C for 30 min and then warmed to room temperature and stirred for 1 h. The reaction was monitored by TLC and H NMR to monitor the reaction. After the reaction was completed, the reaction mixture was hydrolyzed with 6N NaOH and stirred for 1 h. The reaction mixture was extracted with EtOAc. The organic layer was washed with brine and concentrated under reduced pressure to obtain a viscous compound, which was ground with n-pentane and dried to obtain 5-chloro-2-fluorophenylboronic acid as an off-white solid.
5-CHLORO-2-FLUOROPHENYLBORONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 223)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Lastest Price from 5-CHLORO-2-FLUOROPHENYLBORONIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
352535-83-2
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-30 | 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
352535-83-2
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2021-07-13 | 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
352535-83-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
352535-83-2
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
352535-83-2
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- 5-CHLORO-2-FLUOROPHENYLBORONIC ACID
352535-83-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
352535-83-2(5-CHLORO-2-FLUOROPHENYLBORONIC ACID)Related Search:
2-Chloro-4-fluorophenylboronic acid
3-Chloro-2-fluorophenylboronic acid
2-Chloro-6-fluorophenylboronic acid
5-Bromo-3-chloro-2-fluorophenylboronic acid
2-CHLORO-5-FLUOROPHENYLBORONIC ACID
6-Bromo-3-chloro-2-fluorophenylboronic acid
5-Chloro-2,4-difluorobenzeneboronic acid, 97%
4-CHLORO-3-FLUOROPHENYLBORONIC ACID,4-CHLORO-3-FLUOROPHENYLBORONIC ACID 98%
2-CHLORO-3-FLUOROPHENYLBORONIC ACID
3-CHLORO-4-FLUOROPHENYLBORONIC ACID,3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)
1of4
5-Chloro-2-fluorobenzeneboronicacid97%
5-Chloro-2-fluorophenylbornic acid
5-Chloro-2-fluorophenylboronic Acid (contains varying aMounts of Anhydride)
AKOS BRN-0727
5-CHLORO-2-FLUOROBENZENEBORONIC ACID
5-CHLORO-2-FLUOROPHENYLBORONIC ACID
5-Chloro-2-fluorobenzeneboronic acid 97%
57842
Boronic acid, B-(5-chloro-2-fluorophenyl)-
(5-chloro-2-fluorophenyl)boronicaci
5-chloro-2-fluorophenylboric acid
(5-Chloro-2-fluorophenyl)boronic acid - [C2202]
B-(5-Chloro-2-fluorophenyl)boronic acid
352535-83-2
C5H6BClFO2
ClC6H3FBOH2
Aryl
Boronic Acids
Boronic Acids and Derivatives
Organometallic Reagents
blocks
BoronicAcids
FluoroCompounds
Organic boronic acid
Aryl
Boronic Acids
Boronic Acids and Derivatives
