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2-Chloro-3-pyridinamine

2-Chloro-3-pyridinamine Structure
2-Chloro-3-pyridinamine structure
CAS No.
6298-19-7
Chemical Name:
2-Chloro-3-pyridinamine
Synonyms
2-CHLOROPYRIDIN-3-AMINE;3-AMINO-2-CHLOROPYRIDINE;2-CHLORO-3-AMINOPYRIDINE;2-CHLORO-PYRIDIN-3-YLAMINE;Nsc 45407;AKOS MSC-0729;oro-3-pyridyL;TIMTEC-BB SBB004233;2-Chloro-3-pyridinam;OTAVA-BB BB7110951374
CBNumber:
CB3673072
Molecular Formula:
C5H5ClN2
Molecular Weight:
128.56
MDL Number:
MFCD00006238
MOL File:
6298-19-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-24 13:15:37
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2-Chloro-3-pyridinamine Properties

Melting point 76-78 °C (lit.)
Boiling point 130-134 °C (12.7517 mmHg)
Density 130
refractive index 1.5110 (estimate)
Flash point 185 °C
storage temp. 2-8°C
solubility 30g/l
pka 2.42±0.10(Predicted)
form Crystalline Powder, Crystals, and/or Chunks
color Off-white to yellow to pink
PH 7 (30g/l, H2O, 20℃)
Water Solubility Soluble in methanol and water. (30 g/L).
BRN 109814
InChI 1S/C5H5ClN2/c6-5-4(7)2-1-3-8-5/h1-3H,7H2
InChIKey MEQBJJUWDCYIAB-UHFFFAOYSA-N
SMILES Nc1cccnc1Cl
CAS DataBase Reference 6298-19-7(CAS DataBase Reference)
FDA UNII WFH374WQE6
NIST Chemistry Reference 3-Amino-2-chloropyridine(6298-19-7)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H312-H335
Precautionary statements  P280h-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  UN2811
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  29333999
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
1
2 0

2-Chloro-3-pyridinamine price More Price(84)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A46900 3-Amino-2-chloropyridine 98% 6298-19-7 10g $64.1 2026-04-30 Buy
Sigma-Aldrich A46900 3-Amino-2-chloropyridine 98% 6298-19-7 50g $119 2026-04-30 Buy
TCI Chemical A0836 3-Amino-2-chloropyridine >98.0%(GC)(T) 6298-19-7 25g $35 2026-04-30 Buy
Usbiological 258188 3-Amino-2-chloropyridine Asreported 6298-19-7 50g $389 2026-06-03 Buy
Usbiological 258188 3-Amino-2-chloropyridine Asreported 6298-19-7 100g $545 2026-06-03 Buy
Product number Packaging Price Buy
A46900 10g $64.1 Buy
A46900 50g $119 Buy
A0836 25g $35 Buy
258188 50g $389 Buy
258188 100g $545 Buy

2-Chloro-3-pyridinamine Chemical Properties, Uses, Production

Chemical Properties

off-white to yellow to pink crystalline powder,

Uses

It is an intermediate of medicine and agricultural chemicals. It is involved in the Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.

Synthesis

Dissolve 188g (2mol) of 3-aminopyridine in 10% hydrochloric acid: 900g (10%, 2.46mol), completely dissolved and mixed, the volume ratio of the solution to dichloromethane: 400g, sodium hypochlorite solution: 800g (10%, 1.07mol) as a preset unit time volume ratio, and then according to the unit time volume ratio at room temperature (the specific temperature range of 10 -30 the same below) will be pumped into the first stage extraction centrifuge for extraction centrifugation; after that, separate the organic phase and the organic phase continuously. Then, according to the unit time volume ratio at room temperature (the specific temperature range of room temperature is 10 -30 the same below) will be three separate and at the same time continuously pumped into the first stage of the extraction centrifuge extraction centrifugation; after that, the separation of organic phase and aqueous phase, and retain the organic phase, the aqueous phase, industrial hydrochloric acid: 59g (content of 31%, 0.5mol), dichloromethane: 200g, and sodium hypochlorite solution: 400g (10%, 0.54mol) four of the volume ratio, the content of the organic phase: 500g (content of 10 percent, 1.07mol), the volume ratio of the organic phase: 800g (content of 10 percent, 1.07mol) (content 10%, 0.54 mol) as a preset unit time volume ratio, and then in accordance with the unit time volume ratio at room temperature, the four were separately and simultaneously pumped continuously into the second stage of the extraction centrifuge extraction centrifuge; after that, the separation of organic and aqueous phases, and retaining the organic phase, and put the aqueous phase into the next stage of the extraction centrifuge; the subsequent amount of hydrochloric acid, methylene chloride, and sodium hypochlorite solution used in each stage of extraction centrifuge volume The amount of hydrochloric acid, dichloromethane and sodium hypochlorite solution used in each subsequent stage of extraction centrifuge was reduced by half, a total of five stages of continuous extraction reaction (each stage of extraction centrifugal reaction time was 3h), after which the organic phase was combined as 3-amino-2-chloropyridine solution; a total of 962g of solution was obtained, which was analyzed by liquid chromatography with external standard method, and the content of the external standard method was calculated to be 24.4%, the weight of the 3-amino-2-chloropyridine was calculated to be 234.5g, and the molar yield of 3-amino-2-chloropyridine was 91.3 The molar yield of 3-amino-2-chloropyridine was 91.3% (as 3-aminopyridine), purity was 98.4%.

2-Chloro-3-pyridinamine Preparation Products And Raw materials

Raw materials

Preparation Products

Tampramine 3-Iodopyridin-2-amine 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one 3-Amino-2-pyridinecarbonitrile Pirenzepine
2-Chloro-3-(trifluoroMethoxy)pyridine 3-Amino-2-phenylpyridine 3-Amino-2-picoline 2-cyclohexen-1-one, 3-[(2-chloro-3-pyridinyl)amino]-5,5-di 3-[(2-chloro-3-pyridinyl)amino]cyclohex-2-en-1-one
(2-chloropyridin-3-yl)-(4-methoxybenzyl)amine 1-(2-Chloro-pyridin-3-yl)-1H-pyrrole-2-carbaldehyde

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2-Chloro-3-pyridinamine Suppliers

Global Suppliers ( 632)
Supplier Tel Email Country ProdList Advantage
Jiangyin Jufeng Biotechnology Co., Ltd 0519-89891966 13906113265 986329407@qq.com China 55 58
Weifang Siyuan Chemical Co., Ltd. 0536-8888106 17663601818 2354379876@qq.com China 244 58
HEZE DIJADE CHEMCAL CORPORATION 0530-7157019 18678572026 3109950577@qq.com China 18 58
Hengshui Rayson Chemical Technology Co. , Ltd. 0318-8888981 13785822979 1532555757@qq.com China 18 58
Beijing LNP Biotechnology Pharmaceutical Co., Ltd. 15210391295 2531970247@qq.com China 41 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Supplier Advantage
Jiangyin Jufeng Biotechnology Co., Ltd 58
Weifang Siyuan Chemical Co., Ltd. 58
HEZE DIJADE CHEMCAL CORPORATION 58
Hengshui Rayson Chemical Technology Co. , Ltd. 58
Beijing LNP Biotechnology Pharmaceutical Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56

View Latest Price from 2-Chloro-3-pyridinamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chlorpyridin-3-amin pictures 2026-09-02 2-Chlorpyridin-3-amin
6298-19-7
 $6.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Chloro-3-pyridinamine pictures 2026-08-20 2-Chloro-3-pyridinamine
6298-19-7
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Chloro-3-pyridinamine pictures 2026-06-30 2-Chloro-3-pyridinamine
6298-19-7
 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd

2-Chloro-3-pyridinamine Spectrum

2-Chloro-3-pyridinamine(6298-19-7)1HNMR2-Chloro-3-pyridinamine(6298-19-7)13CNMR2-Chloro-3-pyridinamine(6298-19-7)IR12-Chloro-3-pyridinamine(6298-19-7)Raman

6298-19-7 (2-Chloro-3-pyridinamine) Related Search:

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4-Bromo-2-chloro-3-iodopyridine 3-Amino-2-chloro-4-methylpyridine 5-Amino-2-chloro-3-picoline 2-CHLORO-3-FLUORO-4-IODOPYRIDINE 6-Bromo-2-chloro-3-iodopyridine
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3-AMINOCHLOROPYRIDINE AKOS MSC-0729 2-Chloro-3-pyridineaMine Nsc 45407 3-AMINO-2-CHLOROPYRIDINE FOR SYNTHESIS 2-CHLORO-3-AMINOPYRIDINE 2-CHLORO-3-PYRIDYLAMINE 2-Chloro-3-pyridinamine 2-CHLORO-B-PYRIDYLAMINE 2-CHLORO-PYRIDIN-3-YLAMINE OTAVA-BB BB7110951374 TIMTEC-BB SBB004233 3- aMino-2- chlorinepyridine 2-Chloro-3-pyridimine 2-Chloro-3-pyridylamine for synthesis 3-Amino-2-Chloropyridine 2-Chloro-3-Aminopyridine 2-CHLORO-3-PRIDINAMINE 3-Pyridinamine,2-chloro-(9CI) 3-Pyridinamine, 2-chloro- Pyridine, 2-chloro-3-amino- Pyridine, 3-amino-2-chloro- 3-Amino-2-Chlorpyridine 2-Amino-2-chloropyridine 2-CHLORO-3-AMINOPYRIDINE 2-CHLOROPYRIDIN-3-YLAMINE 3-Amino-2-Chloropyridine 99% 3-Amino-2-chloropyridine, 98+% 3-Amino-2-chloropyridine ,99% 3-Amino-2-chloropyridine,96% 2-Chloro-3-pyridinam 3-Amino-2-chloropyridine > oro-3-pyridyL 2-Bromo-3-methyl-7-nitropyridine 2-Chlorpyridin-3-amin 2-Chloro-3-pyridinamine ISO 9001：2015 REACH 3-Amine-2-chloropyridine 3-Amino-2-chloropyridine, 95% 2-CHLOROPYRIDIN-3-AMINE 3-AMINO-2-CHLOROPYRIDINE 6298-19-7 6298-12-7 98-19-7 26298-19-7 C5H5ClN C5H5N2CI HETERO CHLORIDE Halopyridines Chloropyridines Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Building Blocks Building Blocks C5 C5 to C6 Chemical Synthesis Halogenated Heterocycles Pharmaceutical intermediate C5Heterocyclic Building Blocks