Thiodiglycolic acid
- CAS No.
- 505-73-7
- Chemical Name:
- Thiodiglycolic acid
- Synonyms
- 2,2'-Disulfanediyldiacetic acid;DITHIOGLYCOLIC ACID;Vendors;THIODIACETIC ACID;NSC 54088;Dithioglycollicacid;RARECHEM AL BO 1549;Dithiodiglycolicaci;THIODIGLYCOLLIC ACID;Dithiobisacetic acid
- CBNumber:
- CB3688247
- Molecular Formula:
- C4H6O4S2
- Molecular Weight:
- 182.22
- MDL Number:
- MFCD00039607
- MOL File:
- 505-73-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 128-131 °C(lit.) |
|---|---|
| Boiling point | 395.6±27.0 °C(Predicted) |
| Density | 1,19 g/cm3 |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | pK1:3.32;pK2:4.29 (25°C) |
| color | White to Off-White |
| Water Solubility | very faint turbidity |
| Cosmetics Ingredients Functions | REDUCING |
| InChI | InChI=1S/C4H6O4S2/c5-3(6)1-9-10-2-4(7)8/h1-2H2,(H,5,6)(H,7,8) |
| InChIKey | DLLMHEDYJQACRM-UHFFFAOYSA-N |
| SMILES | S(CC(O)=O)SCC(O)=O |
| LogP | 1.390 (est) |
| CAS DataBase Reference | 505-73-7(CAS DataBase Reference) |
| FDA UNII | 7ZZ0LAL4TI |
| EPA Substance Registry System | Acetic acid, 2,2'-dithiobis- (505-73-7) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 34-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-45-36 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | AJ6475000 | |||||||||
| F | 13 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2930.90.4950 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Thiodiglycolic acid price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D5392 | Dithiodiglycolic acid ≥98% | 505-73-7 | 25g | $261 | 2026-04-30 | Buy |
| TCI Chemical | D0945 | Dithiodiglycolic Acid >96.0%(T) | 505-73-7 | 25g | $156 | 2026-04-30 | Buy |
| TRC | TRC-B416620-500MG | 2-(Carboxymethyldisulfanyl)acetic Acid | 505-73-7 | 500mg | $77 | 2026-06-03 | Buy |
| TRC | TRC-B416620-250MG | 2-(Carboxymethyldisulfanyl)acetic Acid | 505-73-7 | 250mg | $64 | 2026-06-03 | Buy |
| TRC | TRC-B416620-2.5G | 2-(Carboxymethyldisulfanyl)acetic Acid | 505-73-7 | 2.5g | $101 | 2026-06-03 | Buy |
Thiodiglycolic acid Chemical Properties, Uses, Production
Uses
Thiodiglycolic acid is a major metabolite of vinyl chloride monomer and ifosfamide (an anti-cancer drug) in human urine. It is used as an analytical reagent for the detection of copper, lead, mercury and silver.
Definition
ChEBI: Thiodiacetic acid is a dicarboxylic acid.
Synthesis
Dithiol dihydroxyacetic acid was prepared as follows: 120g of 2-mercaptoacetic acid, 500g of ethyl acetate and 0.6g of potassium iodide were mixed homogeneously under the condition of temperature of 20C according to mass to form solution A; 80g of hydrogen peroxide with the concentration of 30wt% was added to solution A slowly and the reaction was kept in a warm state for 2h; at the end of the reaction, the obtained solution was washed by 300mL of saturated sodium sulfite solution. After washing and evaporating ethyl acetate under reduced pressure, dithiol dihydroxyacetic acid was obtained.
Thiodiglycolic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Qiyu Biotechnology Co., Ltd. | 13961298435 | zzyqqq@163.com | China | 46 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
View Latest Price from Thiodiglycolic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | THIODIGLYCOLIC ACID
505-73-7
|
$1.00 | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2022-01-15 | Dithiodiglycolic acid
505-73-7
|
1KG | 98.1% | 100 tons | Honest Joy Holdings Limited | ||
![]() |
2020-01-10 | THIODIGLYCOLIC ACID
505-73-7
|
$1.00 | 1KG | 98% HPLC | 10 tons/month | Career Henan Chemical Co |
-

- THIODIGLYCOLIC ACID
505-73-7
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Dithiodiglycolic acid
505-73-7
- $0.00
- 98.1%
- Honest Joy Holdings Limited
-

- THIODIGLYCOLIC ACID
505-73-7
- $1.00
- 98% HPLC
- Career Henan Chemical Co








