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4-Bromotryptophol

4-Bromotryptophol Structure
4-Bromotryptophol structure
CAS No.
202753-56-8
Chemical Name:
4-Bromotryptophol
Synonyms
4-Bromotryptophol;4-BROMOTRYPTOPHOL, 98+%;4-Bromo-1H-indole-3-ethanol;1H-INDOLE-3-ETHANOL, 4-BROMO-;2-(4-bromo-1H-indol-3-yl)ethanol;2-(4-bromo-1H-indol-3-yl)ethan-1-ol
CBNumber:
CB3697889
Molecular Formula:
C10H10BrNO
Molecular Weight:
240.1
MDL Number:
MFCD08275164
MOL File:
202753-56-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:10
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4-Bromotryptophol Properties

Melting point 101-103 °C(Solvent: Ethyl acetate)
Boiling point 411.464±30.00 °C(Press: 760.00 Torr)(predicted)
Density 1.618±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Sealed in dry,Room Temperature
pka 14.824±0.10(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-Bromotryptophol price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 073622 2-(4-Bromo-1H-indol-3-yl)ethanol 202753-56-8 250.00mg $324 2026-05-18 Buy
Matrix Scientific 073622 2-(4-Bromo-1H-indol-3-yl)ethanol 202753-56-8 1.00g $700 2026-05-18 Buy
Matrix Scientific 073622 2-(4-Bromo-1H-indol-3-yl)ethanol 202753-56-8 5.00g $1750 2026-05-18 Buy
Synthonix B52390 2-(4-Bromo-1H-indol-3-yl)ethanol 95+% 202753-56-8 100mg $190 2026-05-06 Buy
Synthonix B52390 2-(4-Bromo-1H-indol-3-yl)ethanol 95+% 202753-56-8 250mg $280 2026-05-06 Buy
Product number Packaging Price Buy
073622 250.00mg $324 Buy
073622 1.00g $700 Buy
073622 5.00g $1750 Buy
B52390 100mg $190 Buy
B52390 250mg $280 Buy

4-Bromotryptophol Chemical Properties,Uses,Production

Synthesis

1H-INDOLE-3-ACETIC ACID,4-BROMO-A-OXO-,ETHYL ESTER

214915-73-8

4-BROMOTRYPTOPHOL

202753-56-8

This embodiment demonstrates the procedure for the synthesis of 2-(4-bromo-1H-indol-3-yl)ethanol from ethyl 2-(4-bromo-3-indolyl)-2-oxoacetate. This was done as follows: lithium aluminum hydride (17.4 mg, 0.459 mmol) was added to a solution of tetrahydrofuran (THF, 1.4 mL) containing ethyl 2-(4-bromo-3-indolyl)-2-oxoacetate (20 mg, 0.0675 mmol), and the reaction mixture was subsequently refluxed for 2 hours. Upon completion of the reaction, the mixture was diluted with ethyl acetate and washed with water. The organic layer was dried with anhydrous magnesium sulfate (MgSO4) and filtered. Evaporation of the filtrate gave the crude product, which was purified by preparative thin layer chromatography (TLC) using a solvent mixture of hexane and ethyl acetate (1:1), resulting in the target product 2-(4-bromo-1H-indol-3-yl)ethanol (10 mg, 63% yield). The structure of the product was confirmed by 1H NMR and HRMS (ESI-MS): 1H NMR (CDCl3) δ 8.12 (1H, br s), 7.32 (1H, dd, J = 0.8 and 7.7 Hz), 7.28 (1H, dd, J = 0.8 and 7.7 Hz), 7.14 (1H, d, J = 2.5 Hz), 7.02 (1H, t, J = 7.8 Hz), 3.97 (2H, q, J = 6.1 Hz), 3.29 (2H, dt, J = 0.6 and 6.5 Hz), 1.46 (1H, t, J = 5.6 Hz); HRMS (ESI-MS m/z) calculated value of C10H11BrNO(M + H)+ 240.0024, measured value 240.0028.

References

[1] Journal of Medicinal Chemistry, 2007, vol. 50, # 8, p. 1810 - 1827
[2] Patent: WO2009/6089, 2009, A2. Location in patent: Page/Page column 26

4-Bromotryptophol Preparation Products And Raw materials

Raw materials

1H-Indole-3-acetic acid,4-bromo-α-oxo-,ethyl ester Ethyl acetate Water Tetrahydrofuran Lithium Aluminum Hydride

Preparation Products

4-Bromotryptophol Suppliers

Global( 63)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Shandong Xiya Chemical Co., Ltd. 4009903999 13395398332 sales@xiyashiji.com China 20788 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai Civic Chemical Technology Co., Ltd. 021-34053660 sale2@labgogo.com China 2018 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Yujinpharma(Tianjin) Technology Co.,Ltd. 13370351217 kungfu1217@1 kungfu1217@163.com China 7995 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Allfluoro Pharmaceutical Company Limited +86-400-0216110 +86-15958047586 sales@allfluoro.com China 11380 58
Changzhou Kechem Bio-Scientific Co., LTD. 0519-68985668 13685222090 sales@kechem.cn China 26012 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Supplier Advantage
Shanghai Topbiochem Technology Co., Ltd 58
Shandong Xiya Chemical Co., Ltd. 60
Amadis Chemical Company Limited 58
Shanghai Civic Chemical Technology Co., Ltd. 58
Aikon International Limited 58
Yujinpharma(Tianjin) Technology Co.,Ltd. 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Allfluoro Pharmaceutical Company Limited 58
Changzhou Kechem Bio-Scientific Co., LTD. 58
Energy Chemical 58

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1H-INDOLE-3-ETHANOL, 4-BROMO- 4-BROMOTRYPTOPHOL, 98+% 2-(4-bromo-1H-indol-3-yl)ethanol 4-Bromo-1H-indole-3-ethanol 2-(4-bromo-1H-indol-3-yl)ethan-1-ol 4-Bromotryptophol 202753-56-8