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ChemicalBook >> CAS DataBase List >>Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Structure
Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- structure
CAS No.
2360527-40-6
Chemical Name:
Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Synonyms
Thalidomide-O-amide-C5-NH2;Thalidomide-O-amido-C5-NH2;N-(5-aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide;N-(5-Aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide;N-(5-aminopentyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide;Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
CBNumber:
CB38252129
Molecular Formula:
C20H24N4O6
Molecular Weight:
416.43
MDL Number:
MFCD32666632
MOL File:
2360527-40-6.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:10
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Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Properties

Boiling point 757.3±60.0 °C(Predicted)
Density 1.368±0.06 g/cm3(Predicted)
pka 10.68±0.40(Predicted)

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm bp-40568 Thalidomide-O-acetamido-C5-amine, HCl salt 2360527-40-6 25MG $320 2026-05-24 Buy
BroadPharm bp-40568 Thalidomide-O-acetamido-C5-amine, HCl salt 2360527-40-6 50MG $540 2026-05-24 Buy
BroadPharm bp-40568 Thalidomide-O-acetamido-C5-amine, HCl salt 2360527-40-6 100MG $980 2026-05-24 Buy
Biorbyt Ltd orb757644 Thalidomide-O-amido-C5-NH2 >98% 2360527-40-6 100mg $700 2026-05-06 Buy
Biorbyt Ltd orb757644 Thalidomide-O-amido-C5-NH2 >98% 2360527-40-6 250mg $1200 2026-05-06 Buy
Product number Packaging Price Buy
bp-40568 25MG $320 Buy
bp-40568 50MG $540 Buy
bp-40568 100MG $980 Buy
orb757644 100mg $700 Buy
orb757644 250mg $1200 Buy

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Chemical Properties, Uses, Production

Uses

Thalidomide-O-amide-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC 50

Cereblon

References

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Suppliers

Global Suppliers ( 10)
Supplier Tel Email Country ProdList Advantage
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9729 58
SuZhou Medinoah Co.,LTD. 0512-69561983 13914027025 zhang_q@medinoah.com China 3925 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
Abosyn 0512-69561983 13914027025 he_qf@medinoah.com China 3000 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 15306536782 3839324846@qq.com China 149 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd +8618235132063 sales@tihondan.com China 3766 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 info@chemextension.com China 42052 58
Supplier Advantage
Shanghai Chaolan Chemical Technology Center 58
SuZhou Medinoah Co.,LTD. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Abosyn 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 58
Jilin Chinese Academy of Sciences-yanshen Technology 58

2360527-40-6 (Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-) Related Search:

E3 Ligase Ligand-Linker Conjugates 24 (TFA) N-(5-Aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride E3 Ligase Ligand-Linker Conjugates 21 E3 Ligase Ligand-Linker Conjugates 19 Thalidomide-O-amido-C4-NH2 hydrochloride
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Thalidomide-linker 15 Thalidomide-O-amido-C8-NH2 hydrochloride Thalidomide-O-amido-PEG4-azide Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
Thalidomide-linker 14 Thalidomide-linker 13 N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide E3 Ligase Ligand-Linker Conjugates 20

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Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Thalidomide-O-amido-C5-NH2 Thalidomide-O-amide-C5-NH2 N-(5-aminopentyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide N-(5-aminopentyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide N-(5-Aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide 2360527-40-6