4-BENZYL-3-HYDROXYMETHYLMORPHOLINE
- CAS No.
- 110167-20-9
- Chemical Name:
- 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE
- Synonyms
- (4-Benzylmorpholin-3-yl);4-Benzyl-3-MorpholineMethanol;4-Bn-3-hydroxymethylmorpholine;4-BENZYL-3-HYDROXYMETHYLMORPHOLINE;N-Benzyl-3-(hydroxymethyl)morpholine;3-Morpholinemethanol, 4-(phenylmethyl)-
- CBNumber:
- CB3846128
- Molecular Formula:
- C12H17NO2
- Molecular Weight:
- 207.27
- MDL Number:
- MFCD04038651
- MOL File:
- 110167-20-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE 97% | 53728 | 0.25G | $46 |
| 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE 97% | 53728 | 1G | $68 |
| 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE 97% | 53728 | 5G | $365 |
| (4-Benzylmorpholin-3-yl)methanol | 145341 | 250.00mg | $252 |
| (4-Benzylmorpholin-3-yl)methanol | 145341 | 1.00g | $831 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319-H315-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501 |
4-BENZYL-3-HYDROXYMETHYLMORPHOLINE price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 53728 | 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE 97% | 110167-20-9 | 0.25G | $46 | 2026-04-30 | Buy |
| AstaTech | 53728 | 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE 97% | 110167-20-9 | 1G | $68 | 2026-04-30 | Buy |
| AstaTech | 53728 | 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE 97% | 110167-20-9 | 5G | $365 | 2026-04-30 | Buy |
| Matrix Scientific | 145341 | (4-Benzylmorpholin-3-yl)methanol | 110167-20-9 | 250.00mg | $252 | 2026-05-18 | Buy |
| Matrix Scientific | 145341 | (4-Benzylmorpholin-3-yl)methanol | 110167-20-9 | 1.00g | $831 | 2026-05-18 | Buy |
4-BENZYL-3-HYDROXYMETHYLMORPHOLINE Chemical Properties,Uses,Production
Synthesis
106910-79-6
110167-20-9
General procedure for the synthesis of N-benzyl-3-hydroxymethylmorpholine from 4-benzyl-5-oxo-3-morpholinecarboxylic acid: triethylamine (7.29 g, 10.0 mL, 72 mmol) was added to a solution of intermediate 58 (17.7 g, 75.3 mmol) in tetrahydrofuran (THF, 300 mL). The reaction system was cooled to 0 °C and the borane dimethyl sulfide complex (~10 M solution of THF, 45 mL, 450 mmol) was slowly added. Subsequently, the reaction mixture was heated to reflux for 16 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and the excess borane was carefully destroyed. The excess THF was evaporated under reduced pressure and the residue was adjusted to strong basicity with 2 M NaOH solution (250 mL) and subsequently extracted with ethyl acetate (EtOAc, 3 x 150 mL). The aqueous phase was acidified to pH 1 with concentrated hydrochloric acid and extracted again. The combined organic phases were washed with brine (150 mL), dried over anhydrous magnesium sulfate (MgSO4), and concentrated under reduced pressure to give N-benzyl-3-hydroxymethylmorpholine (13.5 g, 87% yield) as a clear oil.1H NMR (CDCl3) δ: 7.29-7.16 (5H, m), 4.05 (1H, d, J = 12.8 Hz), 3.88 (1H dd, J = 11.5, 4.5 Hz), 3.78 (1H, m), 3.70-3.53 (2H, m), 3.51-3.40 (2H, m), 3.20 (1H, d, J = 13.2 Hz), 2.68 (1H, dt, J = 12.1, 2.8 Hz), 2.48 (1H, m), 2.27 (1H, m). 2.20-2.15 (1H, bs).
References
[1] Patent: WO2006/114606, 2006, A1. Location in patent: Page/Page column 58-59
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985, p. 2577 - 2580
4-BENZYL-3-HYDROXYMETHYLMORPHOLINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Wuhan Konberd Biotech Co., Ltd | +undefined18986093962 | admin@konberdbio.com | China | 1378 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39021 | 58 |
View Lastest Price from 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-09 | 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE
110167-20-9
|
500g | 98%; 99% | 500g；1kg； 10kg; 25kg | Career Henan Chemical Co |
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- 4-BENZYL-3-HYDROXYMETHYLMORPHOLINE
110167-20-9
- $0.01
- 98%; 99%
- Career Henan Chemical Co
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