(4-Fluorobenzyl)triphenylphosphonium chloride
- CAS No.
- 3462-95-1
- Chemical Name:
- (4-Fluorobenzyl)triphenylphosphonium chloride
- Synonyms
- (4-fluorophenyl)methyl-triphenylphosphanium;(4-Fluorobenzyl)triphenylphosphonium chloride;(4-Fluorophenylmethyl)triphenylphosphoniumchloride;4-Fluorobenzyl triphenylphosphonium chloride, 98+%;(4-fluorophenyl)methyl-triphenylphosphanium,chloride
- CBNumber:
- CB4114174
- Molecular Formula:
- C25H21ClFP
- Molecular Weight:
- 406.86
- MDL Number:
- MFCD00031637
- MOL File:
- 3462-95-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26 | |||||||||
| NFPA 704 |
|
(4-Fluorobenzyl)triphenylphosphonium chloride price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S774154 | (4-FLUOROBENZYL)TRIPHENYLPHOSPHONIUM CHLORIDE AldrichCPR | 3462-95-1 | 1 unit | $32.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | S774154 | (4-FLUOROBENZYL)TRIPHENYLPHOSPHONIUM CHLORIDE Aldrich | 3462-95-1 | 50mg | $29.8 | 2024-03-01 | Buy |
| ChemScene | CS-0040954 | (4-Fluorophenylmethyl)triphenylphosphonium chloride ≥97% | 3462-95-1 | 5g | $19 | 2026-06-04 | Buy |
| ChemScene | CS-0040954 | (4-Fluorophenylmethyl)triphenylphosphonium chloride ≥97% | 3462-95-1 | 10g | $36 | 2026-06-04 | Buy |
| ChemScene | CS-0040954 | (4-Fluorophenylmethyl)triphenylphosphonium chloride ≥97% | 3462-95-1 | 25g | $70 | 2026-06-04 | Buy |
(4-Fluorobenzyl)triphenylphosphonium chloride Chemical Properties, Uses, Production
Chemical Properties
white granular crystalline powder
Synthesis
603-35-0
352-11-4
3462-95-1
General method: As an example of the synthesis of trans-3a: A mixture of 4.0 g (2.78 mmol) of 4-fluorobenzyl chloride and 8.73 g (3.30 mmol) of triphenylphosphine in 12 mL of benzene was refluxed for 48 h to give a white solid. The solid was collected by filtration to give (4-fluorobenzyl)triphenylphosphonium chloride in 82% yield. Then, a mixture of 9.97 g (2.5 mmol) of the above phosphonium salt, 2.37 g (2.2 mmol) of benzaldehyde, and 0.82 g (3.11 mmol) of 18-crown-6 in 56 mL of dichloromethane was stirred vigorously and 27 mL of aqueous 50 % K2CO3 was added slowly. After the addition was completed, the reaction mixture was stirred at room temperature for 72 hours. Upon completion of the reaction, the mixture was poured into water and extracted three times with ethyl acetate. The organic layers were combined and dried with anhydrous MgSO4. The organic solvent was removed by concentration under reduced pressure and the residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane = 1:10) to give a mixture of cis and trans-3a in 95.1% yield. The above mixture was refluxed with a catalytic amount of iodine in benzene for 3 h. After completion of the reaction, the mixture was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=1:10) to afford trans-3a in 92% yield.
References
[1] Tetrahedron, 2013, vol. 69, # 35, p. 7325 - 7332
[2] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 10, p. 3041 - 3045
[3] Journal of Organic Chemistry, 1993, vol. 58, # 21, p. 5643 - 5649
[4] Medicinal Chemistry Research, 2011, vol. 20, # 8, p. 1158 - 1163
[5] Medicinal Chemistry Research, 2011, vol. 20, # 8, p. 1349 - 1356
(4-Fluorobenzyl)triphenylphosphonium chloride Preparation Products And Raw materials
(4-Fluorobenzyl)triphenylphosphonium chloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9848 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd | 18210788515; 18210788515 | zhuzixin999@163.c0m | China | 4999 | 55 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7734 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
View Latest Price from (4-Fluorobenzyl)triphenylphosphonium chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | (4-Fluorobenzyl)triphenylphosphonium chloride
3462-95-1
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-08-07 | (4-Fluorobenzyl)Triphenylphosphonium Chloride
3462-95-1
|
$1.00 | 1KG | 99% | 20 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- (4-Fluorobenzyl)triphenylphosphonium chloride
3462-95-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- (4-Fluorobenzyl)Triphenylphosphonium Chloride
3462-95-1
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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