5-Trifluoromethyl-pyridin-3-ylamine
- CAS No.
- 112110-07-3
- Chemical Name:
- 5-Trifluoromethyl-pyridin-3-ylamine
- Synonyms
- 5-(TrifluoroMethyl)pyridin-3-aMine;5-(Trifluoromethyl)-3-pyridinamine;3-Amino-5-trifluoromethyl-pyridine;3-Pyridinamine,5-(trifluoromethyl);5-(TrifluorMethyl)-3-aMinopyridine;5-Trifluoromethyl-pyridin-3-ylamine;5-Trifluoromethyl-pyridin-3-ylamine ISO 9001：2015 REACH
- CBNumber:
- CB41560086
- Molecular Formula:
- C6H5F3N2
- Molecular Weight:
- 162.11
- MDL Number:
- MFCD00128900
- MOL File:
- 112110-07-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 96% | 51723 | 0.25G | $11 |
| 5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 96% | 51723 | 1G | $15 |
| 5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 96% | 51723 | 5G | $59 |
| 5-(Trifluoromethyl)-3-aminopyridine | 073977 | 1.00g | $328 |
| 5-Trifluoromethyl-pyridin-3-ylamine 97.0% | T10601 | 1g | $28 |
| More product size | |||
| Melting point | 40-41.5 °C |
|---|---|
| Boiling point | 105.5-106 °C(Press: 11 Torr) |
| Density | 1.368 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 3.74±0.20(Predicted) |
| Appearance | Colorless to light yellow <40°C Solid,>41.5°C Liquid |
| InChI | InChI=1S/C6H5F3N2/c7-6(8,9)4-1-5(10)3-11-2-4/h1-3H,10H2 |
| InChIKey | NJFRBMFEAGFNDC-UHFFFAOYSA-N |
| SMILES | C1=NC=C(C(F)(F)F)C=C1N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| RIDADR | UN2811 |
| HS Code | 2933399990 |
5-Trifluoromethyl-pyridin-3-ylamine price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 51723 | 5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 96% | 112110-07-3 | 0.25G | $11 | 2026-04-30 | Buy |
| AstaTech | 51723 | 5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 96% | 112110-07-3 | 1G | $15 | 2026-04-30 | Buy |
| AstaTech | 51723 | 5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 96% | 112110-07-3 | 5G | $59 | 2026-04-30 | Buy |
| Matrix Scientific | 073977 | 5-(Trifluoromethyl)-3-aminopyridine | 112110-07-3 | 1.00g | $328 | 2026-05-18 | Buy |
| Synthonix | T10601 | 5-Trifluoromethyl-pyridin-3-ylamine 97.0% | 112110-07-3 | 1g | $28 | 2026-05-06 | Buy |
5-Trifluoromethyl-pyridin-3-ylamine Chemical Properties,Uses,Production
Synthesis
72587-15-6
112110-07-3
Step Ia: 5-(Trifluoromethyl)-2-chloro-3-nitropyridine (0.850 g, 3.75 mmol) was dissolved in methanol (17 mL), and palladium carbon (800 mg, 10% wetted, 0.375 mmol) was added. The reaction mixture was hydrogenated for 16 h at 60 psi hydrogen pressure and 20 °C. The progress of the reaction was monitored by LCMS to confirm that the starting material (M + H 213/215, 3:1) and hydroxylamine intermediate were completely consumed and a mixture of partially reduced product (M + H 163; UVmax 214, 258, 332 nm) and completely reduced product (M + H 169; no UV absorption) was detected. After completion of the reaction, the reaction mixture was filtered and the filter cake was washed well with methanol. The filtrate was concentrated in vacuum to give 0.74 g of product in the form of HCl salt. Subsequently, the product was purified by preparative HPLC/MS using a 30 mm × 100 mm C18 column; the mobile phase was 20% acetonitrile-water (containing 0.1% NH4OH), with an initial hold of 1 min and a gradient up to 40% over 6 min; the flow rate was 60 mL/min; the detector was set at m/z 163; and the product retention time was 4.4 min. Fractions containing the pure product were collected, combined and concentrated to give 52 mg of the product as an oil in 8% yield.1H NMR (CDCl3) δ 8.26 (s, 1H); 8.24 (d, 1H); 7.15 (t, 1H); 4.00 (s, 2H).
References
[1] Patent: WO2008/79965, 2008, A1. Location in patent: Page/Page column 72-73
[2] Patent: US2006/4018, 2006, A1. Location in patent: Page/Page column 14; 35-36
5-Trifluoromethyl-pyridin-3-ylamine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29793 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
View Lastest Price from 5-Trifluoromethyl-pyridin-3-ylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 5-Trifluoromethyl-pyridin-3-ylamine
112110-07-3
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-04-04 | 5-Trifluoromethyl-pyridin-3-ylamine
112110-07-3
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
|
 |
2020-01-03 | 5-Trifluoromethyl-pyridin-3-ylamine
112110-07-3
|
US $6.60 / KG | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
-
- 5-Trifluoromethyl-pyridin-3-ylamine
112110-07-3
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 5-Trifluoromethyl-pyridin-3-ylamine
112110-07-3
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-Trifluoromethyl-pyridin-3-ylamine
112110-07-3
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co
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