3,5-Dimethyl-4-iodophenol
- CAS No.
- 80826-86-4
- Chemical Name:
- 3,5-Dimethyl-4-iodophenol
- Synonyms
- 4-IODO-3,5-XYLENOL;3,5-Xylenol, 4-iodo-;5-Hydroxy-2-iodo-m-xylene;3,5-Dimethyl-4-iodophenol;4-IODO-3,5-DIMETHYL-PHENOL;Phenol, 4-iodo-3,5-dimethyl-;4-Iodo-3,5-dimethyl-phenol, CAS 80826-86-4;5-Hydroxy-2-iodo-m-xylene, 4-Iodo-3,5-xylenol
- CBNumber:
- CB4201821
- Molecular Formula:
- C8H9IO
- Molecular Weight:
- 248.06
- MDL Number:
- MFCD00174284
- MOL File:
- 80826-86-4.mol
- MSDS File:
- SDS
| Melting point | 129 °C |
|---|---|
| Boiling point | 293.0±28.0 °C(Predicted) |
| Density | 1.740±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | crystalline needles |
| pka | 9.59±0.23(Predicted) |
| color | Faint brown |
| Sensitive | Light Sensitive |
| CAS DataBase Reference | 80826-86-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| Hazard Note | Irritant/Light Sensitive | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2908190090 | |||||||||
| NFPA 704 |
|
3,5-Dimethyl-4-iodophenol price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 62700 | 4-IODO-3,5-DIMETHYL-PHENOL 95% | 80826-86-4 | 1G | $35 | 2026-04-30 | Buy |
| Activate Scientific | AS27749 | 4-Iodo-3,5-dimethylphenol 95% | 80826-86-4 | 1g | $28 | 2026-06-04 | Buy |
| Activate Scientific | AS27749 | 4-Iodo-3,5-dimethylphenol 95% | 80826-86-4 | 5g | $81 | 2026-06-04 | Buy |
| Apolloscientific | OR1104 | 3,5-Dimethyl-4-iodophenol 94% | 80826-86-4 | 1g | $25 | 2026-06-04 | Buy |
| Activate Scientific | AS27749 | 4-Iodo-3,5-dimethylphenol 95% | 80826-86-4 | 25g | $298 | 2026-06-04 | Buy |
3,5-Dimethyl-4-iodophenol Chemical Properties,Uses,Production
Chemical Properties
Light yellow crystalline
Synthesis
108-68-9
80826-86-4
The general procedure for the synthesis of 3,5-dimethyl-4-iodophenol from 3,5-dimethylphenol was as follows: 395 mL of 36% hydrochloric acid was slowly added to a 1 L methanol solution containing 59.1 g (484 mmol) of 3,5-dimethylphenol, which was cooled intermittently to maintain the reaction temperature between 20°C and 30°C. The reaction was then carried out over a period of 5 min by dropwise addition of 54.3 g (327 mmol) of potassium iodide and 33.5 g (157 mmol) of potassium iodate to 500 mL of water. Subsequently, a solution prepared from 54.3 g (327 mmol) of potassium iodide and 33.5 g (157 mmol) of potassium iodate dissolved in 500 mL of water was added dropwise to the reaction system over a period of 5 min. It was observed that the solution gradually turned red and became turbid, followed by the formation of a tan precipitate. The reaction mixture was stirred continuously for 20 h at room temperature before being cooled in an ice bath, the precipitate was collected by filtration and washed with a pre-cooled 2:1 (v:v) water/methanol mixture. The resulting brown solid was purified by several recrystallizations from hot methanol and water, resulting in 36.4 g (15% yield) of white acicular crystals with a melting point of 131-132°C, which were identified as 3,5-dimethyl-4-iodophenol. The structure of the compound was confirmed by 1H NMR (δ, CDCl3) 8.03 (br s, 1H), 6.52 (s, 2H), and 2.35 (s, 6H) as well as by mass spectra (m/e) 248 (M+, 100%), 121, 91, and 77.
References
[1] Catalysis Communications, 2017, vol. 93, p. 1 - 4
[2] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 3, p. 323 - 325
[3] Synthesis, 2001, # 11, p. 1639 - 1644
[4] Journal of Chemical Research, 2004, # 4, p. 294 - 295
[5] Organic Letters, 2015, vol. 17, # 12, p. 2886 - 2889
3,5-Dimethyl-4-iodophenol Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| EnliPharma Technology Co., Ltd | 0551-66399836 18955197623 | sales@enlipharma.com | China | 1875 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7734 | 55 |
View Lastest Price from 3,5-Dimethyl-4-iodophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 3,5-DIMETHYL-4-IODOPHENOL
80826-86-4
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2019-12-20 | 3,5-DIMETHYL-4-IODOPHENOL
80826-86-4
|
$1.00 | 1g | 99% | Career Henan Chemical Co |
-
- 3,5-DIMETHYL-4-IODOPHENOL
80826-86-4
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 3,5-DIMETHYL-4-IODOPHENOL
80826-86-4
- $1.00
- 99%
- Career Henan Chemical Co
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