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Strychnine hydrochloride

CAS No.
1421-86-9
Chemical Name:
Strychnine hydrochloride
Synonyms
STRYCHNINE HCL;Strychnine Hydrochloride Hydrate;Strychnine hydrochloride;Strychnini Hydrochloridum;strychnine,monohydrochloride;Strychnidin-10-onehydrochloride;STRYCHNINE HYDROCHLORIDE USP/EP/BP;strychnidin-10-one,monohydrochloride;Strychnidin-10-one hydrochloride (1:1);Strychnidin-10-one, monohydrochloride (9ci)
CBNumber:
CB4213196
Molecular Formula:
C21H23ClN2O2
Molecular Weight:
370.87
MDL Number:
MFCD00058174
MOL File:
1421-86-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:35

Strychnine hydrochloride Properties

Melting point 295 °C
storage temp. Store at RT
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Sparingly, Slightly)
form Solid
color White to Light Beige
Merck 14,8855
Stability Hygroscopic
InChIKey VLXYTKMPCOQKEM-ZEYGOCRCSA-N
SMILES Cl.[H][C@@]12CC(=O)N3c4ccccc4[C@]56CCN7CC(=CCO1)[C@]([H])(C[C@@]57[H])[C@]2([H])[C@]36[H]
CAS DataBase Reference 1421-86-9(CAS DataBase Reference)
FDA UNII 9651U398A9
EPA Substance Registry System Strychnine hydrochloride (1421-86-9)
UNSPSC Code 12352210
NACRES NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Environment (GHS09)
GHS06,GHS09
Signal word  Danger
Hazard statements  H300+H330-H410
Precautionary statements  P260-P264-P270-P271-P273-P304+P340+P310
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  T+,N
Risk Statements  26/27/28-51/53-50/53-26/28
Safety Statements  22-36/37/39-45-61-60-28-13
RIDADR  UN 1692 6.1/PG 1
WGK Germany  3
RTECS  WL2430000
HazardClass  6.1(a)
PackingGroup  I
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 2 Inhalation
Acute Tox. 2 Oral
Aquatic Acute 1
Aquatic Chronic 1

Strychnine hydrochloride price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S8753 Strychnine hydrochloride 1421-86-9 25g $164 2026-04-30 Buy
Usbiological 289608 Strychnine Hydrochloride Hydrate Asreported 1421-86-9 5g $320 2026-06-03 Buy
Usbiological 289608 Strychnine Hydrochloride Hydrate Asreported 1421-86-9 10g $443 2026-06-03 Buy
Usbiological 289608 Strychnine Hydrochloride Hydrate Asreported 1421-86-9 25g $638 2026-06-03 Buy
Usbiological 289608 Strychnine Hydrochloride Hydrate Asreported 1421-86-9 50g $882 2026-06-03 Buy
Product number Packaging Price Buy
S8753 25g $164 Buy
289608 5g $320 Buy
289608 10g $443 Buy
289608 25g $638 Buy
289608 50g $882 Buy

Strychnine hydrochloride Chemical Properties, Uses, Production

Uses

Strychnine Hydrochloride acts as an antagonist for cholinesterases and beta amyloid aggregation.

Uses

Strychnine hydrochloride has been used as a glycine receptor antagonist in the retina for biophysiological functions. It has also been used to block glutamatergic, GABAergic and glycinergic receptors and gap junctions.

Definition

ChEBI: A hydrochloride obtained by combining strychnine with one molar equivalent of hydrogen chloride.

Biological Activity

Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α 7 receptors and non-competitive antagonism at α 4 β 2 receptors.

Biochem/physiol Actions

Strychnine is a potent convulsant, which is extracted from Strychnos nux vomica seeds. At high doses, the compound causes convulsions and ultimately death due to respiratory paralysis. Strychnine acts as a respiratory, circulatory and digestive stimulant.

Strychnine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 71)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 18080918076 800078821@qq.com China 9706 55
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 sales@uhnshanghai.com China 997 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55

View Latest Price from Strychnine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
STRYCHNINE HYDROCHLORIDE USP/EP/BP pictures 2026-08-20 STRYCHNINE HYDROCHLORIDE USP/EP/BP
1421-86-9
$1.10 1g 99.9% 100 Tons min Dideu Industries Group Limited
 Strychnidin-10-one,hydrochloride (1:1) pictures 2023-05-04 Strychnidin-10-one,hydrochloride (1:1)
1421-86-9
$40.00-48.00 1Kg/Bag 99% 200tons Guangzhou Sunton Biotechnology Co., Ltd.
(4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline-14-one:hydrochloride Strychnidin-10-one hydrochloride (1:1) (4aR,4a1R,5aS,8aR,8a1S,15aS)-4a1,5,5a,7,8,8a1,15,15a-Octahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14(4aH)-one hydrochloride Strychnidin-10-one, monohydrochloride (9ci) Strychnidin-10-onehydrochloride strychnidin-10-one,monohydrochloride strychnine,monohydrochloride STRYCHNINE HYDROCHLORIDE USP/EP/BP Strychnine Hydrochloride (1.0 mg/mL in Methanol) Strychnini Hydrochloridum Strychnine Hydrochloride Hydrate STRYCHNINE HCL Strychnine Hydrochloride (1mg/ml in Methanol) Strychnine hydrochloride 1421-86-9 C21H22N2O2HClxH2O C21H23N2O2Cl C21H22N2O2HCl C21H23ClN2O2 Cell Signaling and Neuroscience Cell Biology BioChemical Ion Channels Ligand-Gated Ion Channels GABA and Glycine Receptor Modulators Optical Resolution Alkaloids Indole Alkaloids for Resolution of Acids GABA and Glycine Receptor ModulatorsNeurotransmission Glycinergics Ion Channels Ligand-Gated Ion Channels Neurotransmitters chiral Alkaloids Biochemistry for Resolution of Acids Indole Alkaloids Optical Resolution Synthetic Organic Chemistry