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5-Hydroxy-3,4-dihydroquinolin-2(1H)-one

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one structure

CAS No.: 30389-33-4

Chemical Name:: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one

Synonyms: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one;5-Hydroxy-3,4-dihydrocarbostyryl;Carteolol EP Impurity B;5-HYDROXY-3;Carteolol int;Carteolol Impurity 2;Carteolol Intermediate;Carteolol HCl Impurity;Aripiprazole impurity 7;Aripiprazole Impurity 14

CBNumber:: CB4259600

Molecular Formula:: C9H9NO2

Molecular Weight:: 163.17

MDL Number:: MFCD01862194

MOL File:: 30389-33-4.mol

TDS File:: TDS

Last updated:2026-05-28 03:12:17

Product description	Number	Pack Size	Price
3,4-Dihydro-5-hydroxy-1H-quinolin-2-one	D5669	1G	$69
3,4-Dihydro-5-hydroxy-1H-quinolin-2-one	D5669	5G	$346
5-Hydroxy-3,4-dihydro-2(1H)-quinolinone	TRC-H941410-5G	5g	$581
5-Hydroxy-3,4-dihydro-2(1H)-quinolinone	TRC-H941410-250MG	250mg	$103
5-Hydroxy-3,4-dihydro-2(1H)-quinolinone	TRC-H941410-2.5G	2.5g	$351
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5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Properties

Melting point	225-227°C
Boiling point	381.2±42.0 °C(Predicted)
Density	1.282±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	9.63±0.20(Predicted)
color	White to Off-White
InChI	InChI=1S/C9H9NO2/c11-8-3-1-2-7-6(8)4-5-9(12)10-7/h1-3,11H,4-5H2,(H,10,12)
InChIKey	UTTJAIFHRUAFED-UHFFFAOYSA-N
SMILES	N1C2=C(C(O)=CC=C2)CCC1=O
CAS DataBase Reference	30389-33-4(CAS DataBase Reference)
FDA UNII	BH76UU379C

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319-H335
Precautionary statements	P271-P260-P280
Hazard Codes	Xi
HS Code	2933499090

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D5669	3,4-Dihydro-5-hydroxy-1H-quinolin-2-one	30389-33-4	1G	$69	2026-04-30	Buy
TCI Chemical	D5669	3,4-Dihydro-5-hydroxy-1H-quinolin-2-one	30389-33-4	5G	$346	2026-04-30	Buy
TRC	TRC-H941410-5G	5-Hydroxy-3,4-dihydro-2(1H)-quinolinone	30389-33-4	5g	$581	2026-06-03	Buy
TRC	TRC-H941410-250MG	5-Hydroxy-3,4-dihydro-2(1H)-quinolinone	30389-33-4	250mg	$103	2026-06-03	Buy
TRC	TRC-H941410-2.5G	5-Hydroxy-3,4-dihydro-2(1H)-quinolinone	30389-33-4	2.5g	$351	2026-06-03	Buy

Product number	Packaging	Price	Buy
D5669	1G	$69	Buy
D5669	5G	$346	Buy
TRC-H941410-5G	5g	$581	Buy
TRC-H941410-250MG	250mg	$103	Buy
TRC-H941410-2.5G	2.5g	$351	Buy

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Chemical Properties,Uses,Production

Chemical Properties

Off-white Solid

Uses

Carteolol (C184450) metabolite.

Definition

ChEBI: 5-hydroxy-3,4-dihydro-2(1h)-quinolinone is a quinolone and a hydroxyquinoline.

Synthesis

To a 100 ml three-necked flask were added 3,4,7,8-tetrahydro-2,5 (1 H, 6Η) -quinoline dione (0.02 mol) and cyclohexane (25 ml). After stirring to dissolve in the ice bath for 10min, slowly add a dropwise N-bromosuccinimide (0.03mol) in cyclohexane (5ml), and reflux for 3h at the end of the dropwise addition. After completion of the reaction by TLC, cool down to room temperature. Water was added (the amount was 0.7 times the volume of the reactant), and the mixture was allowed to stand with stirring. The aqueous layer was extracted with ethyl acetate (1 × the volume of the aqueous layer 4 times), and the organic layers were combined. Anhydrous sulfuric acid Calcium was dried and filtered, the filtrate was evaporated to remove the solvent, and the residue was dried to give an off-white solid as a 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one (Yield 92.7percent).

References

[1] Patent: CN107337639, 2017, A. Location in patent: Paragraph 0120; 0127; 0139; 0150; 0161; 0171; 0172; 0183

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one synthesis

Synthesis of 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one from 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Preparation Products And Raw materials

Raw materials

3-CHLORO-N-(3-METHOXYPHENYL)PROPANAMIDE 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE N-Bromosuccinimide Cyclohexane

Preparation Products

5-HYDROXY-2(1H)-QUINOLINONE

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Suppliers

Global( 223)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2945	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +86-13651600618	sales@worldyachem.com	China	963	58
Shaanxi Dideu Medichem Co. Ltd	+86-17392712779	1097@dideu.com	China	3989	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9666	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
Shanghai UCHEM Inc.	+86-18930848214 +86-021-56762820	sales@myuchem.com	China	8927	58
AFINE CHEMICALS LIMITED	+86-571-85134551 +86-18958018566	info@afinechem.com	China	15050	58
Finetech Industry Limited	+86-27-8746-5837 +86-18627785180	info@finetechnology-ind.com	China	9539	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58

Supplier	Advantage
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shanghai UCHEM Inc.	58
AFINE CHEMICALS LIMITED	58
Finetech Industry Limited	58
BOC Sciences	58

View Lastest Price from 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-25	5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 30389-33-4	$65.00-650.00	1KG	0.99	20 tons	Zibo Hangyu Biotechnology Development Co., Ltd
2025-12-24	5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 30389-33-4		1KG	99.0%	1000 tons	Shaanxi Dideu Medichem Co. Ltd
2025-08-21	5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 30389-33-4		1kg	99% HPLC	1000kg	HangZhou RunYan Pharma Technology Co.,LTD.

5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE
30389-33-4
$65.00-650.00
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE
30389-33-4
$0.10
99.0%
Shaanxi Dideu Medichem Co. Ltd

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one
30389-33-4
$0.00
99% HPLC
HangZhou RunYan Pharma Technology Co.,LTD.

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Spectrum

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one(30389-33-4)¹HNMR

30389-33-4(5-Hydroxy-3,4-dihydroquinolin-2(1H)-one)Related Search:

5-HYDROXY-2(1H)-QUINOLINONE 8-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane BroMide 7-Hydroxyquinolinone 7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE Brexpiprazole Impurity 20

Thianaphthene Brexpiprazole Impurity Brexpiprazole Impurity 2 7-(4-chlorobutoxy)-1-{4-[(2-oxo-1,2-dihydroquinolin-7-yl)oxy]butyl}-1,2-dihydroquinolin-2-one Brexpiprazole sulfoxide impurity

(E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE 8-hydroxy-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one 4-Bromobenzo[b]thiophene 7,7'-(butane-1,4-diylbis(oxy))bis(quinolin-2(1H)-one) 2(1H)-Quinolinone,7-(4-chlorobutoxy)-

Brexpiprazole (3,4)-Dihydro-2(1H)-quinolinone 1,4-di(benzo[b]thiophen-4-yl)piperazine Brexpiprazole Impurity

1of4

3,4-DIHYDRO-5-HYDROXY-2(1H)-QUINOLINONE 5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 5-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE 3,4-Dihydro-5-hydroxycarbostyril 5-HYDROXY-3,4-DIHYDRO-2-QUINOLINE 5-Hydroxy-2(1H)-3,4-dihydroquinolinone 3,4-Dihydro-5-hydroxy-1H-quinolin-2-one 5-Hydroxy-3,4-dihydrocarbostyril 3,4-Dihydro-5-hydroxyquinolin-2(1H)-one 5-Hydroxy-1,2,3,4-tetrahydroquinoline-2-one 5-hydroxy-1,2,3,4-tetrahydro-2-quinolinone Carteolol int Brexpiprazole Impurity 70 5-hydroxy-1,2,3,4-tetrahydroquinolin-2-one 5-Hydroxy-3,4-dihydrocarbostyryl 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 2(1H)-Quinolinone, 3,4-dihydro-5-hydroxy- Carteolol HCl EP Impurity B Carbostyril,3,4-dihydro-5-hydroxy- (8CI) Aripiprazole Impurity 14 Carteolol Intermediate 5-Hydroxy-3,4-dihydroquinolin-2(1H) Aripiprazole impurity 7 Carteolol Hydrochloride impurity B Carteolol EP Impurity B 5-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one(For export only) 4-DIHYDRO-1H-QUINOLIN-2-ONE 5-HYDROXY-3 5-hydroxy-3,4-dihydro-1-h-quinoline Aripiprazole impurities1768 Carteolol Impurity 2 Carteolol EP Impurity B（Aripiprazole Impurity 26） 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone (5-HQ) 5-Hydroxy-3,4-dihydro-2(1h)- quinolinone, 98% (Custom work) Carteolol HCl Impurity 5-HYDROXY-3,4-DIHYDROQUINOLINE-2(1H)-ONE Carteolol Hydrochloride Impurity 2(Carteolol Hydrochloride EP Impurity B ) 30389-33-4 pharmacetical Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals API