7-Hydroxyquinolinone
- CAS No.
- 70500-72-0
- Chemical Name:
- 7-Hydroxyquinolinone
- Synonyms
- 7-Hydroxyquinolin-2(1H)-one;quinoline-2,7-diol;2,7-DIHYDROXYQUINOLINE;7-Hydroxy-;7-hydroxyquinolinone;7-Hydroxycarbostyril;7-hydroxy-2(1H)-Quino;7- hydroxy-2-quinolone;7-HYDROXY-2-QUINOLINONE;N1-(2,3-dichlorophenyl)-N2
- CBNumber:
- CB6404930
- Molecular Formula:
- C9H7NO2
- Molecular Weight:
- 161.16
- MDL Number:
- MFCD04117979
- MOL File:
- 70500-72-0.mol
| Product description | Number | Pack Size | Price |
| 7-Hydroxyquinoline-(1H)-2-one | H953255 | 10g | $365 |
| 2,7-DIHYDROXYQUINOLINE 95.00% | CHM0966005 | 5MG | $495.78 |
| 7-Hydroxyquinolinone 95% | 144291 | 5g | $903 |
| 7-Hydroxyquinolinone 95% | 144291 | 25g | $2709 |
| 2,7-Dihydroxyquinoline 95+% | 072934 | 1g | $12 |
| More product size | |||
| Melting point | 187-192°C |
|---|---|
| Boiling point | 426.8±45.0 °C(Predicted) |
| Density | 1.337±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| pka | 9.32±0.20(Predicted) |
| form | Solid |
| color | Off-White to Pale Yellow |
| Water Solubility | Water: Insoluble |
| Major Application | pharmaceutical |
| InChI | InChI=1S/C9H7NO2/c11-7-3-1-6-2-4-9(12)10-8(6)5-7/h1-5,11H,(H,10,12) |
| InChIKey | DBSPUDKBNOZFMX-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC(O)=C2)C=CC1=O |
| CAS DataBase Reference | 70500-72-0(CAS DataBase Reference) |
| FDA UNII | 3B25C3NP9L |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| WGK Germany | WGK 3 |
| HS Code | 29334900 |
| Storage Class | 11 - Combustible Solids |
7-Hydroxyquinolinone price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | H953255 | 7-Hydroxyquinoline-(1H)-2-one | 70500-72-0 | 10g | $365 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0966005 | 2,7-DIHYDROXYQUINOLINE 95.00% | 70500-72-0 | 5MG | $495.78 | 2021-12-16 | Buy |
| Matrix Scientific | 144291 | 7-Hydroxyquinolinone 95% | 70500-72-0 | 5g | $903 | 2021-12-16 | Buy |
| Matrix Scientific | 144291 | 7-Hydroxyquinolinone 95% | 70500-72-0 | 25g | $2709 | 2021-12-16 | Buy |
| Matrix Scientific | 072934 | 2,7-Dihydroxyquinoline 95+% | 70500-72-0 | 1g | $12 | 2021-12-16 | Buy |
7-Hydroxyquinolinone Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
7-Hydroxyquinolone is a substituted carbostyril derivative used as a pharmaceutical intermediate. It is an impurity of aripiprazole quinolinone.
Definition
ChEBI: 7-hydroxyquinolin-2(1H)-one is a monohydroxyquinoline and a quinolone.
Synthesis
127033-74-3
70500-72-0
General procedure for the synthesis of 7-hydroxyquinolin-2(1H)-one from N-(3-methoxyphenyl)cinnamamide: Aluminum trichloride (3.16 g, 23.69 mmol) was added batchwise to a suspension of chlorobenzene (30 mL) of compound 3 (1 g, 3.95 mmol) in an ice bath. The reaction mixture was gradually warmed up to 120 °C and kept at reflux for 3 hours. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the reaction mixture was concentrated to dryness under reduced pressure and the residue was purified by silica gel column chromatography to afford compound 4 in 54% yield.
References
[1] Synthesis, 1997, # 1, p. 87 - 90
[2] Tetrahedron Letters, 1999, vol. 40, # 24, p. 4505 - 4506
[3] Journal of Medicinal Chemistry, 2015, vol. 58, # 14, p. 5561 - 5578
[4] Patent: CN108101926, 2018, A. Location in patent: Paragraph 0033; 0034; 0035
[5] Patent: WO2008/24481, 2008, A2. Location in patent: Page/Page column 32
7-Hydroxyquinolinone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD | +8613572219112 | info@pushanshiye.com | China | 165 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13635 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
View Lastest Price from 7-Hydroxyquinolinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-04 | 7-Hydroxycarbostyril
70500-72-0
|
US $0.00 / removed | 97.54% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-12-01 | 7-Hydroxyquinolinone
70500-72-0
|
US $0.00 / kg | 1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-11-18 | 7-Hydroxyquinolinone
70500-72-0
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited |
-
- 7-Hydroxycarbostyril
70500-72-0
- US $0.00 / removed
- 97.54%
- TargetMol Chemicals Inc.
-
- 7-Hydroxyquinolinone
70500-72-0
- US $0.00 / kg
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 7-Hydroxyquinolinone
70500-72-0
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
