Stachydrine hydrochloride
- CAS No.
- 4136-37-2
- Chemical Name:
- Stachydrine hydrochloride
- Synonyms
- StachydrineHCl;Stachydrine chloride;Stachydrine hydrochL;Herba leonurl extract;Cadabine hydrochloride;Stachydrine hydrochlor;Stachydrine hydrochlori;Stachydrine chloride-RM;Stachytine hydrochloride;Stachydrine hydrichloride
- CBNumber:
- CB4290780
- Molecular Formula:
- C7H14ClNO2
- Molecular Weight:
- 179.64
- MDL Number:
- MFCD21609192
- MOL File:
- 4136-37-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 225°C |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water |
| Merck | 14,8771 |
| Stability | Hygroscopic |
| InChI | InChI=1S/C7H13NO2.ClH/c1-8(2)5-3-4-6(8)7(9)10;/h6H,3-5H2,1-2H3;1H |
| InChIKey | DUNMULOWUUIQIL-UHFFFAOYSA-N |
| SMILES | C1(CCC[N+]1(C)C)C([O-])=O.Cl |
| CAS DataBase Reference | 4136-37-2(CAS DataBase Reference) |
| FDA UNII | 19Z024IC5E |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 20-22 |
| Safety Statements | 22-45-36/37/39 |
| HS Code | 29339900 |
Stachydrine hydrochloride price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89799 | Stachydrine chloride phyproof? Reference Substance | 4136-37-2 | 25MG | $327 | 2026-04-30 | Buy |
| TCI Chemical | S0358 | Stachydrine Hydrochloride | 4136-37-2 | 10mg | $29 | 2026-04-30 | Buy |
| Cayman Chemical | 20506 | Stachydrine (hydrochloride) ≥95% | 100mg | $70 | 2026-04-30 | Buy | |
| Cayman Chemical | 20506 | Stachydrine (hydrochloride) ≥95% | 250mg | $153 | 2026-04-30 | Buy | |
| Cayman Chemical | 20506 | Stachydrine (hydrochloride) ≥95% | 500mg | $268 | 2026-04-30 | Buy |
Stachydrine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, easily soluble in methanol and water, derived from motherwort.
Uses
Stachydrine Chloride is a constituent of the Chinese herb leonurus heterophyllus sweet. its used in clinics to support blood circulation and dispel blood stasis.
Biological Activity
stachydrine is an anti-metastatic agent.stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of c. leonurus, and many other asian plants and fruits.
in vitro
the aim of a previous study was to investigate the effects of stachydrine (sta) on norepinephrine (ne) induced hypertrophy and the changes of calcium transients in neonatal rat cardiomyocytes. results showed that ne treatment could increase protein synthesis, cell surface area, the expression level of β-mhc and β/α-mhc ratio and these effects were attenuated by sta treatment. in addition, ne-induced hypertrophy was associated with accelerated decay of ca2+-transient, increased phospholamban expression, increased ca2+-transient amplitude, hyper-phosphorylation, increased intracellular camp level, as well as pka overactivation. all of these effects could be inhibited by sta treatment significantly [1].
in vivo
previous study evaluated the effect of stachydrine on the expression of caspase-9 and 12 in rats with unilateral ureteral obstruction. results showed that degree of renal interstitial fibrosis, serum creatinine, blood urea nitrogen, the renal tubular interstitial damage index, and expression of caspase-9 and 12 in the stachydrine-treatment groups were significantly decreased [2].
target
IL Receptor | T-bet | RORγt | GATA-3 | Foxp3
IC 50
p65; Human Endogenous Metabolite
References
[1] zhang, c. ,shan, x.-l.,liao, y.-l., et al. effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients. bmc complement. altern. med. 14, 474 (2014).
[2] zhang c, lu y, zhou yj, tong qq, qu c, kang tj. the effect of stachydrine on the expression of caspase-12 in rats with unilateral ureteral obstruction. j urol. 2014 nov;192(5):1549-54.
Stachydrine hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haochen Biotechnology Co., Ltd | 18710685966 18710685966 | 511325867@qq.com | China | 319 | 58 |
| Xi 'an Xinmengchen Biotechnology Co., LTD | 15002922985 | 511325867@qq.com | China | 305 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Lastest Price from Stachydrine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Stachydrine hydrochloride
4136-37-2
|
1KG | ≥98% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd.
|
||
 |
2026-08-25 | STACHYDRINE HYDROCHLORIDE
4136-37-2
|
1kg | 0.99 | 1000kg | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-08-07 | STACHYDRINE HYDROCHLORIDE
4136-37-2
|
$1.00-70.00 | 1KG | 99%+ | 1658KG | Shaanxi Dideu Medichem Co. Ltd |
-
- Stachydrine hydrochloride
4136-37-2
- $0.00
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- STACHYDRINE HYDROCHLORIDE
4136-37-2
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- STACHYDRINE HYDROCHLORIDE
4136-37-2
- $1.00-70.00
- 99%+
- Shaanxi Dideu Medichem Co. Ltd
