ChemicalBook >> CAS DataBase List >>6-Bromoisatin

6-Bromoisatin

6-Bromoisatin structure

CAS No.: 6326-79-0

Chemical Name:: 6-Bromoisatin

Synonyms: 6-BROMOINDOLINE-2,3-DIONE;6-BROMO-1H-INDOLE-2,3-DIONE;SW-8;SWF-8;AKOS B01843;AKOS B018432;6-BROMOISATIN;BROMOISATIN(6-);6-Bromoisatin 97%;BUTTPARK 50\07-95

CBNumber:: CB4300641

Molecular Formula:: C8H4BrNO2

Molecular Weight:: 226.03

MDL Number:: MFCD01631138

MOL File:: 6326-79-0.mol

Last updated:2026-01-13 11:19:57

Product description	Number	Pack Size	Price
6-Bromoisatin >97.0%(GC)(T)	B2424	5g	$107
6-Bromoisatin >97.0%(GC)(T)	B2424	25g	$333
6-BromoIsatin	B684485	2g	$50
6-Bromoisatin	FB19026	2g	$50
6-Bromo-1H-indole-2,3-dione 95+%	030121	5g	$24
More product size

Request For Quotation

6-Bromoisatin Properties

Melting point	274°C
Density	1.826±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	8.83±0.20(Predicted)
form	Solid
color	Dark Yellow
InChI	InChI=1S/C8H4BrNO2/c9-4-1-2-5-6(3-4)10-8(12)7(5)11/h1-3H,(H,10,11,12)
InChIKey	HVPQMLZLINVIHW-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC(Br)=C2)C(=O)C1=O
CAS DataBase Reference	6326-79-0(CAS DataBase Reference)
FDA UNII	UVA4QW7PH2
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H317-H319

Precautionary statements

P261-P264-P270-P271-P272-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501

Hazard Codes

Xi,Xn

Risk Statements

22-41-43

Safety Statements

22-24/25-36/37/39-26

WGK Germany

WGK 3

HazardClass

IRRITANT

HS Code

2933998090

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2

NFPA 704

	0
2		0

6-Bromoisatin price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B2424	6-Bromoisatin >97.0%(GC)(T)	6326-79-0	5g	$107	2025-07-31	Buy
TCI Chemical	B2424	6-Bromoisatin >97.0%(GC)(T)	6326-79-0	25g	$333	2025-07-31	Buy
TRC	B684485	6-BromoIsatin	6326-79-0	2g	$50	2021-12-16	Buy
Biosynth Carbosynth	FB19026	6-Bromoisatin	6326-79-0	2g	$50	2021-12-16	Buy
Matrix Scientific	030121	6-Bromo-1H-indole-2,3-dione 95+%	6326-79-0	5g	$24	2021-12-16	Buy

Product number	Packaging	Price	Buy
B2424	5g	$107	Buy
B2424	25g	$333	Buy
B684485	2g	$50	Buy
FB19026	2g	$50	Buy
030121	5g	$24	Buy

6-Bromoisatin Chemical Properties,Uses,Production

Chemical Properties

Orange Powder

Uses

Antimicrobial

Biological Functions

6-Bromoisatin inhibited proliferation of HT29 cells at IC50 223 μM (0.05 mg/mL) and induced apoptosis without increasing caspase 3/7 activity. In vivo 6-bromoisatin (0.05 mg/g) was found to significantly enhance the apoptotic index (p ≤ 0.001) and reduced cell proliferation (p ≤ 0.01) in the distal colon.

Synthesis

Acetamide, N-(3-bromophenyl)-2-(hydroxyimino)-

65971-74-6

6326-79-0

Step 2: N-(3-bromophenyl)-2-hydroxyiminoacetamide (55 g, 0.2272 mol) was added to concentrated sulfuric acid (275 mL) and the temperature was maintained at 50 °C. The temperature of the reaction system was then raised to 90 °C for 3 hours. Upon completion of the reaction, the reaction mixture was slowly poured into ice water and a yellow precipitate was precipitated. The precipitate was collected by filtration and dried to give 6-bromodihydroindole-2,3-dione as a yellow solid (50 g, 98% yield). The resulting product can be used directly in the subsequent reaction without further purification.

Purification Methods

6-Bromoisatin recrystallises from AcOH (yellow needles). It is a plant growth substance. IR in CHCl3 has 1320 and 3440cm-1. [Sadler J Org max Chem 21 169 1956, Beilstein 21 III/IV 5012.]

References

[1] Patent: WO2012/58671, 2012, A1. Location in patent: Page/Page column 91
[2] Patent: WO2011/119704, 2011, A1. Location in patent: Page/Page column 36-37
[3] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 5, p. 549 - 554
[4] Medicinal Chemistry, 2014, vol. 10, # 5, p. 484 - 496
[5] Patent: US2014/38952, 2014, A1. Location in patent: Page/Page column 0154-0155

6-Bromoisatin synthesis

Synthesis of 6-Bromoisatin from 6-Bromo-1,3-dihydro-2H-indol-2-one

6-Bromoisatin Preparation Products And Raw materials

Raw materials

Chloral hydrate Sodium sulfate Hydrochloric acid Hydroxylamine hydrochloride 3-Bromoaniline

Sulfuric acid Acetamide, N-(3-bromophenyl)-2-(hydroxyimino)- 4-BROMOISATIN (E)-6,6'-dibromo-[3,3'-biindolinylidene]-2,2'-dione 6-Bromo-1,3-dihydro-2H-indol-2-one

6-Bromo-1H-indole

1of3

Preparation Products

7-bromoquinoline-4-carboxylic acid 6-Bromo-1-methylindolin-2-one

6-Bromoisatin Suppliers

Global( 310)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hefei Lbao Physical & Chemical Science Co.,Ltd	+1-5184799099	lbaochemicals@gmail.com	China	674	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2176	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Hefei Lbao Physical & Chemical Science Co.,Ltd	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Time Chemicals CO., Ltd.	55
Nanjing Finetech Chemical Co., Ltd.	55
career henan chemical co	58
Accela ChemBio Inc.	58
Changzhou Ditong Chemical Co.,Ltd	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 6-Bromoisatin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-15	6-Bromoisatin 6326-79-0	US $0.00 / kg	1kg	98%	Customise	Hefei Lbao Physical & Chemical Science Co.,Ltd
2025-09-25	6-Bromoisatin 6326-79-0	US $36.00-1.50 / kg	1kg	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2025-05-23	6-Bromoisatin 6326-79-0	US $10.00 / kg	1kg	99%	20 ton	Hebei Zhuanglai Chemical Trading Co Ltd

6-Bromoisatin
6326-79-0
US $0.00 / kg
98%
Hefei Lbao Physical & Chemical Science Co.,Ltd

6-Bromoisatin
6326-79-0
US $36.00-1.50 / kg
99%
Henan Fengda Chemical Co., Ltd

6-Bromoisatin
6326-79-0
US $10.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co Ltd

6-Bromoisatin Spectrum

6-Bromoisatin(6326-79-0)¹HNMR 6-Bromoisatin(6326-79-0)FT-IR

6326-79-0(6-Bromoisatin)Related Search:

Indometacin Indole Isatoic Anhydride 4'-Bromoacetophenone 6-Bromo-1H-indole

Indole-3-acetic acid 2-Bromoacetophenone Indirubin 7-Bromoisatin 97% 4-Bromoisatin 98%,4-BROMOISATIN

1-(2,6-Dichlorophenyl)-2-hydroindole BOC,BZL-L-ALA-OH 1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- Pyrido[4,3-d]pyrimidin-4(1H)-one (9CI) 1H-Pyrrole-2-acetic acid, 3-(methoxycarbonyl)-1-methyl-, methyl ester

3-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine 7-bromo-4-(trifluoromethyl)-1H-indole 2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

1of4

BUTTPARK 50\07-95 BROMOISATIN(6-) 6-BROMOINDOLE-2,3-DIONE 6-BROMOINDOLINE-2,3-DIONE 6-BROMOISATIN 6-BROMO ISATINIC ANHYDRIDE 6-BROMO-1H-INDOLE-2,3-DIONE AKOS B018432 AKOS B01843 6-Bromoisatin 97% 6-BROMO-1H-INDOLE-2,3-DIONE 97.0%(MIN)(HPLC) 6-BROMOISATINMONOHYDRATE 6-Bromo-2,3-Indolinedione 6-Bromoisatin ,98% 6-broMo-2,3-dihydro-1H-indole-2,3-dione 6-BroMoisatin 6-BroMo indole-2,3-dione 6-Bromo-1H-indole-2,3-dione, 6-Bromoindolin-2,3-dione 6- broMoindigo carMine 6-broMineindigo carMine 6 - broMine indigo red 6-BroMoisatin, 97.0%(GC&T 1H-Indole-2,3-dione, 6-bromo- 6-Bromoisatin/97% 6-Bromoisatin > SWF-8 SW-8 6-Bromo Indigo Red Tazobactam Impurity 66 6-Bromo-1H-indole-2,3-dione 6326-79-0 Simple Indoles Indoles Heterocyclic Compounds Indoles Simple Indoles Heterocycles Phenyls & Phenyl-Het Fused Ring Systems Indane/Indanone and Derivatives Halides Aminomethyl's Phenyls & Phenyl-Het