Fmoc-Asn(Trt)-OH
- CAS No.
- 132388-59-1
- Chemical Name:
- Fmoc-Asn(Trt)-OH
- Synonyms
- FMOC-ASN(TRT)-OH;FMOC-ASN(TRT);FMOC-L-ASN(TRT)-OH;N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N4-trityl-L-asparagine;(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoic acid;FMOC-N-TRITYL-L-ASPARAGINE;Nα-Fmoc-Nγ-trityl-L-asparagine;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)carbamoyl]propanoic acid;L-Asn(Trt);FMoc-Asn(Tre)
- CBNumber:
- CB4331632
- Molecular Formula:
- C38H32N2O5
- Molecular Weight:
- 596.67
- MDL Number:
- MFCD00077049
- MOL File:
- 132388-59-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 8.52044 | 25g | $112 |
| FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 8.52044 | 100g | $274 |
| FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 8.52044 | 250g | $590 |
| FMOC-Asn(Trt)-OH N-α-Fmoc-N-ß-trityl-L-asparagine Novabiochem® | 8.52044 | 500 g | $1080 |
| FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 8.52044 | 1kg | $1940 |
| More product size | |||
| Melting point | 201-204 °C(lit.) |
|---|---|
| alpha | -16 º (c=1, MeOH) |
| Boiling point | 858.1±65.0 °C(Predicted) |
| Density | 1.271±0.06 g/cm3(Predicted) |
| refractive index | -19 ° (C=1, DMF) |
| storage temp. | 2-8°C |
| solubility | <0.00005g/l |
| form | powder to crystal |
| pka | 3.79±0.10(Predicted) |
| color | White to Almost white |
| optical activity | [α]20/D 15.0±1°, c = 1% in methanol |
| Water Solubility | <0.00005g/L |
| BRN | 4343823 |
| Major Application | peptide synthesis |
| InChIKey | KJYAFJQCGPUXJY-UUWRZZSWSA-N |
| SMILES | C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 |
| CAS DataBase Reference | 132388-59-1(CAS DataBase Reference) |
| FDA UNII | 5R94765WYL |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H411 | |||||||||
| Precautionary statements | P273-P391-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Risk Statements | 53 | |||||||||
| Safety Statements | 24/25-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 2 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 2924 29 70 | |||||||||
| HazardClass | IRRITANT | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Chronic 2 | |||||||||
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg | |||||||||
| NFPA 704 |
|
Fmoc-Asn(Trt)-OH price More Price(93)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 25g | $112 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 100g | $274 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 250g | $590 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-ß-trityl-L-asparagine Novabiochem® | 132388-59-1 | 500 g | $1080 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.52044 | FMOC-Asn(Trt)-OH N-α-Fmoc-N-?-trityl-L-asparagine Novabiochem? | 132388-59-1 | 1kg | $1940 | 2026-04-30 | Buy |
Fmoc-Asn(Trt)-OH Chemical Properties,Uses,Production
Description
Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.
Chemical Properties
white crystal powde
Uses
Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.
Preparation
Synthesis of Fmoc-Asn(Trt)-OH:
Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
Fmoc-Asn(Trt)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lanxi Xingnuo Import and Export Trading Co., Ltd | +86-15888978871 +86-13901546477 | sales@xingnuotraders.com | China | 163 | 58 |
| Chengdu ZY Biochemical Technology Co., Ltd. | +86-86-2888626688 +8618980008884 | xuehaiying@zybiochem.com | China | 177 | 58 |
| Dingwang Technology (Wuhan) Co., Ltd. | +undefined-27-2786652399 +undefined13627115097 | market02@senwayer.com | China | 887 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1006 | 58 |
| Chengdu Baishixing Science and Technology Industry Co.,Ltd | +86-15008457246 | yuki@cd-bsx.com | China | 53 | 58 |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8618382028708 | ni@enlaibio.com | China | 1100 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
View Lastest Price from Fmoc-Asn(Trt)-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-03 | Fmoc-L-Asn(Trt)-OH
132388-59-1
|
1kg | 98% | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
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2026-01-04 | Fmoc-N-β-trityl-L-asparagine
132388-59-1
|
1Box | 99% | 200kg | Hangzhou ICH Biofarm Co., Ltd | ||
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2025-08-22 | Fmoc-Asn(trt)-OH
132388-59-1
|
25gram | 99% HPLC | 25 gram | Dingwang Technology (Wuhan) Co., Ltd. |
-

- Fmoc-L-Asn(Trt)-OH
132388-59-1
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-

- Fmoc-N-β-trityl-L-asparagine
132388-59-1
- $0.00
- 99%
- Hangzhou ICH Biofarm Co., Ltd
-

- Fmoc-Asn(trt)-OH
132388-59-1
- $0.00
- 99% HPLC
- Dingwang Technology (Wuhan) Co., Ltd.





