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AZD4320

AZD4320 Structure
AZD4320 structure
CAS No.
1357576-48-7
Chemical Name:
AZD4320
Synonyms
AZD4320;AZD4320, 10 mM in DMSO;Bcl-2 Family,Inhibitor,inhibit,AZD4320,AZD 4320,AZD-4320;4-(4-((R)-(4'-Chloro-[1,1'-biphenyl]-2-yl)(hydroxy)methyl)piperidin-1-yl)-N-((4-(((R)-4-((2-hydroxyethyl)(methyl)amino)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide;Benzamide, 4-[4-[(R)-(4'-chloro[1,1'-biphenyl]-2-yl)hydroxymethyl]-1-piperidinyl]-N-[[4-[[(1R)-3-[(2-hydroxyethyl)methylamino]-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]-
CBNumber:
CB43380958
Molecular Formula:
C45H48ClF3N4O7S3
Molecular Weight:
945.53
MDL Number:
MFCD31657439
MOL File:
1357576-48-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
AZD 4320 ≥98% 41978 1mg $43
AZD 4320 ≥98% 41978 5mg $183
AZD 4320 ≥98% 41978 10mg $258
AZD 4320 ≥98% 41978 25mg $537
AZD4320 HEC57648 25mg $1086.5
Request For Quotation

AZD4320 Properties

Density 1.46±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 125 mg/mL (132.20 mM)
form Solid
pka 4.70±0.10(Predicted)
color White to off-white
FDA UNII LH1ZTY91OR

AZD4320 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 41978 AZD 4320 ≥98% 1357576-48-7 1mg $43 2026-04-30 Buy
Cayman Chemical 41978 AZD 4320 ≥98% 1357576-48-7 5mg $183 2026-04-30 Buy
Cayman Chemical 41978 AZD 4320 ≥98% 1357576-48-7 10mg $258 2026-04-30 Buy
Cayman Chemical 41978 AZD 4320 ≥98% 1357576-48-7 25mg $537 2026-04-30 Buy
Biosynth HEC57648 AZD4320 1357576-48-7 25mg $1086.5 2026-06-04 Buy
Product number Packaging Price Buy
41978 1mg $43 Buy
41978 5mg $183 Buy
41978 10mg $258 Buy
41978 25mg $537 Buy
HEC57648 25mg $1086.5 Buy

AZD4320 Chemical Properties,Uses,Production

Uses

AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC50s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively.

IC 50

BCL2: 17 nM (IC50, KPUM-UH1 cells); BCLxL: 17 nM (IC50, KPUM-UH1 cells)

References

[1] Takimoto-Shimomura T, et al. Dual targeting of bromodomain-containing 4 by AZD5153 and BCL2 by AZD4320 against B-cell lymphomas concomitantly overexpressing c-MYC and BCL2. Invest New Drugs. 2018 Jun 21. DOI:10.1007/s10637-018-0623-8

AZD4320 synthesis

1357575-27-9
1357576-48-7
Synthesis of AZD4320 from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

AZD4320 Preparation Products And Raw materials

Raw materials

1-Piperidinecarboxylic acid, 4-[(4'-chloro[1,1'-biphenyl]-2-yl)hydroxymethyl]-, 1,1-dimethylethyl ester ethyl (R)-4-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)(hydroxy)methyl)piperidin-1-yl)benzoate (4'-chloro-[1,1'-biphenyl]-2-yl)(piperidin-4-yl)methanol (R)-4-(4-((4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzoicacid 4-Fluoro-3-(trifluoromethylsulfonyl) benzenesulfonamide
Methyl 3-(benzyloxycarbonyl)-4-(phenylthio)butanoate 2'-BROMO-4-CHLORO-BIPHENYL 1-FLUORO-2-[(TRIFLUOROMETHYL)SULFONYL]BENZENE 4-Chlorophenylboronic acid 1,2-Dibromobenzene

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Preparation Products

AZD4320 Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Career Henan Chemica Co 		+86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38999 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4854 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Zhejiang Huida Biotech Co., LTD 58

View Lastest Price from AZD4320 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AZD4320 pictures 2026-07-27 AZD4320
1357576-48-7
 $67.00-196.00 98.13% 10g TargetMol Chemicals Inc.
AZD4320 pictures 2026-07-27 AZD4320
1357576-48-7
 $67.00-196.00 98.13% 10g TargetMol Chemicals Inc.
  • AZD4320 pictures
  • AZD4320
    1357576-48-7
  • $67.00-196.00
  • 98.13%
  • TargetMol Chemicals Inc.
  • AZD4320 pictures
  • AZD4320
    1357576-48-7
  • $67.00-196.00
  • 98.13%
  • TargetMol Chemicals Inc.

AZD4320 Spectrum

AZD4320(1357576-48-7)1HNMR

1357576-48-7(AZD4320)Related Search:

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AZD-5904

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AZD4320 Benzamide, 4-[4-[(R)-(4'-chloro[1,1'-biphenyl]-2-yl)hydroxymethyl]-1-piperidinyl]-N-[[4-[[(1R)-3-[(2-hydroxyethyl)methylamino]-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]- Bcl-2 Family,Inhibitor,inhibit,AZD4320,AZD 4320,AZD-4320 4-(4-((R)-(4'-Chloro-[1,1'-biphenyl]-2-yl)(hydroxy)methyl)piperidin-1-yl)-N-((4-(((R)-4-((2-hydroxyethyl)(methyl)amino)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide AZD4320, 10 mM in DMSO 1357576-48-7 C45H48ClF3N4O7S3