Fmoc-Ala-aldehyde
- CAS No.
- 146803-41-0
- Chemical Name:
- Fmoc-Ala-aldehyde
- Synonyms
- Fmoc-Ala-CHO;Fmoc-Ala-aldehyde;Fmoc-L-Ala-aldehyde;(S)-2-(Fmoc-amino)propanal;(9H-Fluoren-9-yl)MethOxy]Carbonyl Ala-aldehyde;(S)-(9H-fluoren-9-yl)methyl 1-oxopropan-2-ylcarbamate;(9H-fluoren-9-yl)methyl N-[(2S)-1-oxopropan-2-yl]carbamate;Carbamic acid, N-[(1S)-1-methyl-2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester
- CBNumber:
- CB4342182
- Molecular Formula:
- C18H17NO3
- Molecular Weight:
- 295.33
- MDL Number:
- MFCD01318541
- MOL File:
- 146803-41-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Fmoc-Ala-aldehyde price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 277503 | Fmoc-L-Alaninal Asreported | 146803-41-0 | 100mg | $369 | 2026-06-03 | Buy |
| Usbiological | 277503 | Fmoc-L-Alaninal Asreported | 146803-41-0 | 250mg | $468 | 2026-06-03 | Buy |
| Usbiological | 277503 | Fmoc-L-Alaninal Asreported | 146803-41-0 | 500mg | $631 | 2026-06-03 | Buy |
| Usbiological | 277503 | Fmoc-L-Alaninal Asreported | 146803-41-0 | 1g | $1045 | 2026-06-03 | Buy |
| Usbiological | 277503 | Fmoc-L-Alaninal Asreported | 146803-41-0 | 2g | $1467 | 2026-06-03 | Buy |
Fmoc-Ala-aldehyde Chemical Properties, Uses, Production
Uses
Fmoc-ala-aldehyde acts as an intermediate in the synthesis of α-amino aldehydes and peptide aldehydes.
Synthesis
161529-13-1
146803-41-0
To an anhydrous dichloromethane (10 mL) solution of oxalyl chloride (1.89 g, 15.0 mmol) was added anhydrous dichloromethane (10 mL) solution of dimethyl sulfoxide (1.2 g, 15.0 mmol) dropwise at -65 °C. After stirring for 30 minutes, anhydrous dichloromethane (20 mL) solution of N-fluorenylmethoxycarbonyl-L-alaninol (3.0 g, 10.0 mmol) was added slowly dropwise. After continued stirring for 2 h, triethylamine (3.0 g, 30 mmol) was added dropwise, followed by gradual warming of the reaction mixture to room temperature. Upon completion of the reaction, the reaction was quenched with water and extracted with dichloromethane (3 x 100 mL). The organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure to give the white solid product methyl (S)-(9H-fluoren-9-yl)methyl(1-oxopropan-2-yl)carbamate (2.8 g, 94.9% yield).
References
[1] Patent: WO2011/69063, 2011, A2. Location in patent: Page/Page column 82
[2] Synthetic Communications, 2007, vol. 37, # 20, p. 3493 - 3499
[3] Tetrahedron Letters, 2000, vol. 41, # 32, p. 6131 - 6135
[4] Tetrahedron Letters, 2000, vol. 41, # 9, p. 1359 - 1362
[5] Journal of Medicinal Chemistry, 2007, vol. 50, # 23, p. 5627 - 5643
Fmoc-Ala-aldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Fmoc-Ala-aldehyde Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Chengdu Chuangkecheng Biological Technology Co., Ltd. | 028-028-0000000 13008177686 | sales@ckcbiotech.com | China | 899 | 55 |
| Shanghai GL Peptide Ltd. | +86-21-61263310 13764994101 | fisherwang@glschina.com | China | 8059 | 55 |
| BioPharmaMatrix,Inc. | 0510-86010668 13395169561; | sales@biopharmamatrix.com | China | 5019 | 55 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. | 13632427122;13414494621 | chenchao02lzu@126.com | China | 137 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | sale03@alfachem.cn | China | 9872 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
146803-41-0 (Fmoc-Ala-aldehyde) Related Search:
1of4
