ChemicalBook >> CAS DataBase List >>7-Ethoxycoumarin

7-Ethoxycoumarin

7-Ethoxycoumarin structure

CAS No.: 31005-02-4

Chemical Name:: 7-Ethoxycoumarin

Synonyms: ETHOXYCOUMARIN;7-ETHOXYCOUMARIN;ETHOXYCOUMARIN, 7-;Ethylumbelliferone;Coumarin, 7-ethoxy-;7-Ethoxycoumarin>7-Ethoxycoumarin ,99%;7-ethoxychromen-2-one;ETHOXYCOUMARIN, 7-(RG);7-O-Ethylumbelliferone

CBNumber:: CB4357665

Molecular Formula:: C11H10O3

Molecular Weight:: 190.2

MDL Number:: MFCD00006877

MOL File:: 31005-02-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-17 09:03:53

Request For Quotation

7-Ethoxycoumarin Properties

Melting point	88-90 °C (lit.)
Boiling point	265.69°C (rough estimate)
Density	1.1803 (rough estimate)
refractive index	1.4260 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form	Solid
color	Off-White to Pale Brown
Water Solubility	Soluble in hot methanol (very faint turbidity), 95% ethanol (50 mg/ml), DMF, and DMSO. Insoluble in water.
BRN	146200
InChI	1S/C11H10O3/c1-2-13-9-5-3-8-4-6-11(12)14-10(8)7-9/h3-7H,2H2,1H3
InChIKey	LIFAQMGORKPVDH-UHFFFAOYSA-N
SMILES	CCOc1ccc2C=CC(=O)Oc2c1
LogP	2.310 (est)
CAS DataBase Reference	31005-02-4(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	C8K66XCQ6L
UNSPSC Code	41116107
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P271-P280

Hazard Codes

Safety Statements

22-24/25

WGK Germany

Hazard Note

Irritant

TSCA

Yes

HS Code

29329990

Storage Class

11 - Combustible Solids

NFPA 704

	1
0		0

7-Ethoxycoumarin price More Price(63)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E1379	7-Ethoxycoumarin	31005-02-4	25mg	$33.5	2026-04-30	Buy
Sigma-Aldrich	E1379	7-Ethoxycoumarin	31005-02-4	1g	$368	2026-04-30	Buy
Sigma-Aldrich	41577	7-Ethoxycoumarin analytical standard	31005-02-4	10 mg	$107	2026-04-30	Buy
TCI Chemical	E0538	7-Ethoxycoumarin >97.0%(GC)	31005-02-4	5g	$131	2026-04-30	Buy
TCI Chemical	E0538	7-Ethoxycoumarin >97.0%(GC)	31005-02-4	25g	$393	2026-04-30	Buy

Product number	Packaging	Price	Buy
E1379	25mg	$33.5	Buy
E1379	1g	$368	Buy
41577	10 mg	$107	Buy
E0538	5g	$131	Buy
E0538	25g	$393	Buy

7-Ethoxycoumarin Chemical Properties, Uses, Production

Description

7-Ethoxycoumarin is oneof the general substrates for liver cytochrome P450 enzymes, and it is known that CYP1A1,1A2, and 2B1, drug inducedtypes (b-naphthoflavone, isosafrole, and phenobarbital,re-spectively, in rat liver) are mainly responsible for the ECDE activity in the liver.

Chemical Properties

BEIGE CRYSTALLINE POWDER

Uses

7-Ethoxycoumarin is a substrate for CYP2B6 used in fluorometric assays of microsomal monooxygenase activity.

Uses

7-Ethoxycoumarin is commonly used for metabolism studies, including hepatocyte studies, liver perfusion techniques and cytochrome P450 studies.
7-Ethoxycoumarin has been used to study the functional activity of recombinant P450. ) It has also been used as an internal standard for in vitro S-warfarin 7-hydroxylation and high performance liquid chromatography (HPLC) analysis.

Definition

ChEBI: 7-ethoxycoumarin is a member of the class of coumarins that is umbelliferone in which the hydroxy group at position 7 is replaced by an ethoxy group. It is an aromatic ether and a member of coumarins. It derives from an umbelliferone.

Biochem/physiol Actions

7-Ethoxycoumarin is a cytochrome P450 substrate.

Metabolism

7-Ethoxycoumarin is metabolized by many cytochrome P450 enzymes active in foreign compound metabolism and has been used as a prototypic substrate to monitor P450 (P450) activity in both hepatic and extrahepatic tissues.
The in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.
Use of 7-Ethoxycoumarin to Monitor Multiple Enzymes in the Human CYP1, CYP2, and CYP3 Families

7-Ethoxycoumarin synthesis

Synthesis of 7-Ethoxycoumarin from Bromoethane and 7-Hydroxycoumarin

7-Ethoxycoumarin Preparation Products And Raw materials

Raw materials

7-Hydroxycoumarin Acetone Potassium carbonate Bromoethane 2H-1-Benzopyran-2-thione, 7-ethoxy-

Diethyl acetylenedicarboxylate 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran Carbon tetrachloride Bromoacetaldehyde diethyl acetal Iodoethane

1of2

Preparation Products

7-Ethoxycoumarin Suppliers

Global Suppliers ( 209)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66
Adamas Reagent, Ltd.	59
Chemsky (shanghai) International Co.,Ltd	60
Shandong Xiya Chemical Co., Ltd	57
Syntechem Co.,Ltd	57

View Latest Price from 7-Ethoxycoumarin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	7-ETHOXYCOUMARIN 31005-02-4	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2026-07-17	7-Ethoxycoumarin 31005-02-4	$45.00		99.67%	10g	TargetMol Chemicals Inc.
2025-06-27	7-Ethoxycoumarin 31005-02-4		1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

7-ETHOXYCOUMARIN
31005-02-4
$1.10
99.00%
Dideu Industries Group Limited

7-Ethoxycoumarin
31005-02-4
$45.00
99.67%
TargetMol Chemicals Inc.

7-Ethoxycoumarin
31005-02-4
99%
Hebei Chuanghai Biotechnology Co., Ltd

7-Ethoxycoumarin Spectrum

7-Ethoxycoumarin(31005-02-4)MS 7-Ethoxycoumarin(31005-02-4)¹HNMR 7-Ethoxycoumarin(31005-02-4)¹³CNMR 7-Ethoxycoumarin(31005-02-4)IR1 7-Ethoxycoumarin(31005-02-4)IR2 7-Ethoxycoumarin(31005-02-4)Raman

31005-02-4 (7-Ethoxycoumarin) Related Search:

4-METHYL-7-ETHOXYCOUMARIN,METHYL-7-ETHOXYCOUMARIN, 4-(SG),METHYL-7-ETHOXYCOUMARIN, 4- 7-Ethoxycoumarin 4-Ethoxycoumarin 7-Hydroxycoumarin glucoside 4-Methylumbelliferyl-beta-D-glucuronide

4-Methylumbelliferyl-beta-D-glucopyranoside 7-Acetoxy-4-methylcoumarin AFLATOXIN G1 Esculetin dibenzyl ether (4-Methylumbelliferyl)-α-L-iduronide cyclohexylammonium salt

4-Methylumbelliferyl-N,N',N''-triacetyl-beta-chitotrioside 6,7-Diacetoxy-4-methylcoumarin Ethyl 7-acetoxycoumarin-3-carboxylate 3-Acetyl-7-[beta-D-glucopyranosyloxy]-coumarin 4-Methylumbelliferyl 2-Amino-2-deoxy-a-D-glucopyranoside

7-Ethoxycoumarin-d5 7-(Carboxymethoxy)-4-methylcoumarin 3-Carboxyumbelliferyl acetate

1of4

7-ETHOXY-1-BENZOPYRAN-2-ONE 7-ETHOXY-1-BENZOPYRANE-2-ONE 7-ETHOXYCOUMARIN JR-8408, 7-Ethoxycoumarin, 97% ETHOXYCOUMARIN, 7- 7-ETHOXYCOUMARIN, 99.5% 7-ETHOXYCOUMARIN, FOR FLUORESCENCE 7-ETHOXYCOUMARIN CRYSTALLINE 7-Ethoxycoumarin, 99.50% ETHOXYCOUMARIN, 7-(RG) ETHOXYCOUMARIN 7-ethoxy-2H-chroMen-2-one 2H-1-Benzopyran-2-one, 7-ethoxy- Coumarin, 7-ethoxy- Ethylumbelliferone 7-Ethoxycoumarin ,99% 7-Ethoxy-2H-1-benzopyran-2-one 7-O-Ethylumbelliferone 7-Ethoxycoumarin> 7-ETHOXYCOUMARIN ISO 9001：2015 REACH 7-ethoxychromen-2-one 7-Ethoxycoumarin extrapure, 98% 7-Ethoxycoumarin, ≥ 97.0% 7-Ethoxycoumarin, 10 mM in DMSO 7-ethoxy-2H-benzenebenzo2-pyranone 31005-02-4 Fluorescent Enzyme Substrates Fluorescent Probes, Labels, Particles and Stains Fluorescent Enzyme Substrates for Spectroscopy Detection Alphabetical Biochemicals and Reagents BioChemical Building block Coumarin Aromatics Compounds Aromatics