2-Amino-5-chlorobenzophenone oxime
- CAS No.
- 18097-52-4
- Chemical Name:
- 2-Amino-5-chlorobenzophenone oxime
- Synonyms
- AKOS 90376;TIMTEC-BB SBB003174;Oxazepam Impurity 3;Diazepam Impurity 20;Mixtureofsyn-andanti-isomeres;2-Amino-5-Chlor-Benzophenonoxim;2-Amino-5-Chlorobenzopheone Oxime;2-Amino-5-chlorobenzophenone oxime;2-AMINO-5-CHLOROBENZOPHENEONE OXIME;2-Amino-5-chlorobenzophenoneα-oxime-,(Z)-
- CBNumber:
- CB4368100
- Molecular Formula:
- C13H11ClN2O
- Molecular Weight:
- 246.69
- MDL Number:
- MFCD00014780
- MOL File:
- 18097-52-4.mol
- MSDS File:
- SDS
| Melting point | 117-120oC |
|---|---|
| Boiling point | 434.9±45.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 10.20±0.28(Predicted) |
| color | Pale Yellow to Light Yellow |
| FDA UNII | P6TT5B5JCX |
| EPA Substance Registry System | Methanone, (2-amino-5-chlorophenyl)phenyl-, oxime (18097-52-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| Safety Statements | 24/25 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29280090 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2-Amino-5-chlorobenzophenone oxime price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S413445 | 2-AMINO-5-CHLOROBENZOPHENONE OXIME (MIXTURE OF SYN AND ANTI ISOMERS) AldrichCPR | 18097-52-4 | 1 unit | $197 | 2026-04-30 | Buy |
| Sigma-Aldrich | S413445 | 2-AMINO-5-CHLOROBENZOPHENONE OXIME (MIXTURE OF SYN AND ANTI ISOMERS) Aldrich | 18097-52-4 | 1g | $179 | 2024-03-01 | Buy |
| Usbiological | 002114 | 2-Amino-5-chlorobenzophenone Oxime | 18097-52-4 | 1g | $312 | 2026-06-03 | Buy |
| Biosynth | FA67520 | 2-Amino-5-chlorobenzophenone oxime | 18097-52-4 | 5g | $181.45 | 2026-06-04 | Buy |
| Biosynth | FA67520 | 2-Amino-5-chlorobenzophenone oxime | 18097-52-4 | 10g | $317.5 | 2026-06-04 | Buy |
2-Amino-5-chlorobenzophenone oxime Chemical Properties,Uses,Production
Description
2-Amino-5-Chlorobenzophenone is in the form of a yellow-brown crystalline powder. Its melting point is 98-100°C. It is used to produce intermediates for the synthesis of Oxazolam drug and intermediates for psychotherapeutic agents, such as chlorodiazepoxide and diazepam.1,2
Reference
- R. Liao, Synthetic method of Oxazolam drug intermediate 2-amino-5-chlorobenzophenone, Patent CN105461576A
- S. Nakanishi, W. E. Barth, Process for preparing 6-chloromethyl-4-phenylquinazoline-3-oxide and intermediates therefor, Patent US3932325A
Chemical Properties
yellow crystalline powder
Uses
Intermediate in the preparation of Chlordiazepoxide (C327050) and its metabolites.
Definition
ChEBI: (2-amino-5-chlorophenyl)(phenyl)methanone oxime is a diarylmethane.
Synthesis Reference(s)
The Journal of Organic Chemistry, 30, p. 3957, 1965 DOI: 10.1021/jo01022a519
2-Amino-5-chlorobenzophenone oxime Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 | sales@fartop.net | China | 2227 | 55 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| Nanjing River Chemical Co., Ltd. | 13951936332 18305166317 | info@serpharm.com | China | 493 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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