Diflufenican
- CAS No.
- 83164-33-4
- Chemical Name:
- Diflufenican
- Synonyms
- dff;Diflufenica;Kwarc;Couger;Brodal;Canyon;Legato;JAVELIN;FENICAN;B 38544
- CBNumber:
- CB4370925
- Molecular Formula:
- C19H11F5N2O2
- Molecular Weight:
- 394.29
- MDL Number:
- MFCD01311804
- MOL File:
- 83164-33-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 110°C |
|---|---|
| Boiling point | 376.2±42.0 °C(Predicted) |
| Density | 1.4301 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), |
| form | Solid |
| pka | 9.03±0.70(Predicted) |
| color | Off-White |
| Merck | 14,3144 |
| BRN | 4212494 |
| Henry's Law Constant | 6.4×101 mol/(m3Pa) at 25℃, Keshavarz et al. (2022) |
| Major Application |
agriculture environmental |
| InChI | InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27) |
| InChIKey | WYEHFWKAOXOVJD-UHFFFAOYSA-N |
| SMILES | C1(OC2=CC=CC(C(F)(F)F)=C2)=NC=CC=C1C(NC1=CC=C(F)C=C1F)=O |
| LogP | 4.900 |
| CAS DataBase Reference | 83164-33-4(CAS DataBase Reference) |
| FDA UNII | 3T8D1VDO6K |
| EPA Substance Registry System | 3-Pyridinecarboxamide, N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]- (83164-33-4) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312-H412 | |||||||||
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352+P312 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Risk Statements | 52/53 | |||||||||
| Safety Statements | 61 | |||||||||
| RIDADR | UN3077(solid); UN3082 (liquid) | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | US4589800 | |||||||||
| HS Code | 2933.39.2500 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
|||||||||
| Toxicity | LD50 in mice, rats (mg/kg): >1000, >2000 orally; in rats (mg/kg): >2000 dermally (Cramp) | |||||||||
| NFPA 704 |
|
Diflufenican price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CRM45751 | Diflufenican certified reference material, TraceCERT?, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | 83164-33-4 | 50mg | $79.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 45751 | Diflufenican PESTANAL | 83164-33-4 | 100mg | $89.5 | 2026-04-30 | Buy |
| TCI Chemical | D4108 | Diflufenican | 83164-33-4 | 1G | $31 | 2026-04-30 | Buy |
| TCI Chemical | D4108 | Diflufenican | 83164-33-4 | 25G | $258 | 2026-04-30 | Buy |
| TRC | TRC-D445640-500MG | Diflufenican | 83164-33-4 | 500mg | $108 | 2026-06-03 | Buy |
Diflufenican Chemical Properties, Uses, Production
Description
The diflufenican is a selective contact and residual herbicide that can be applied pre-emergence and post-emergence. It can be absorbed through the shoots of the germinating seeding with limited translocation. Its mode of mechanism is via a bleaching action through inhibiting the carotenoid biosynthesis process, further blocking photosynthesis process and causing plant death. It is used for the treatment of some broad leaved weeds such as Stellaria media (Chickweed), Veronica Spp (Speedwell), Viola spp, Geranium spp (Cranesbill) and Laminum spp (Dead nettles). It has been approved for use on barley, durum wheat, rye, triticale and wheat. It can be used in combination with isoproturon or other cereal herbicides.
References
http://www.globachem.com/en/agrochemicals/d/resource/diflufenican
http://www.agchemaccess.com/Diflufenican
Uses
Herbicide.
Uses
Pre and post emergence foliar absorbed herbicide for winter weed control in cereal crops; carotenoid biosynthesis inhibitor.
Definition
ChEBI: A pyridinecarboxamide that is pyridine-3-carboxamide substituted by a 2,4-difluorophenyl group at the carbamoyl nitrogen and a 3-(trifluoromethyl)phenoxy group at position 2.
Production Methods
Diflufenican is commercially produced through a multi-step chemical synthesis involving fluorinated aromatic compounds and nicotinanilide intermediates. The process typically starts with the construction of a difluorophenyl ring, which is then coupled with a nicotinamide derivative via selective substitution and condensation reactions.
Agricultural Uses
Herbicide: Pre-and post-emergence foliar absorbed herbicide for winter weed control in cereal crops; carotenoid biosynthesis inhibitor. Used on crops such as apples, apricot, barley, beans (dry), broad beans, cherry, grapefruit, lemon, lime, loquat, natsudaidai (whole), nectarine, orange, peach, pear, peas, persimon, plum,quince, rye, soybeans, unshu orange and wheat. Not currently registered in the U.S. Approved for use in EU countries.
Trade name
ARDENT®; BACARA®; CAPTURE® Diflufenican; COUGAR®; CUB®; GRENADIER®; IONIZ®; JAVELIN®; JAVELIN® GOLD; KWARC®; MB-38183®; M&B 38544®; PANTHER®; QUARTZ®; SPEARHEAD®
Mechanism of action
Selective contact and residual action. Bleaching - Carotenoid biosynthesis inhibitor.
Pesticide Type
Herbicide
Diflufenican Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9336 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
View Latest Price from Diflufenican manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | Diflufenican
83164-33-4
|
$6.00-8.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2026-07-14 | diflufenican
83164-33-4
|
1kg | 99 | 20tons | Qingdao Trust Agri Chemical Co.,Ltd | ||
![]() |
2026-06-02 | Diflufenican
83164-33-4
|
$50.00 | 99.62% | 10g | TargetMol Chemicals Inc. |
-

- Diflufenican
83164-33-4
- $6.00-8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- diflufenican
83164-33-4
- $0.00
- 99
- Qingdao Trust Agri Chemical Co.,Ltd
-

- Diflufenican
83164-33-4
- $50.00
- 99.62%
- TargetMol Chemicals Inc.








