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2-CHLORO-5-PHENYL-PYRIMIDINE

2-CHLORO-5-PHENYL-PYRIMIDINE Structure
2-CHLORO-5-PHENYL-PYRIMIDINE structure
CAS No.
22536-62-5
Chemical Name:
2-CHLORO-5-PHENYL-PYRIMIDINE
Synonyms
2-Chloro-5-phenyl-pyridimine;2-CHLORO-5-PHENYL-PYRIMIDINE;PyriMidine,2-chloro-5-phenyl-;2-CHLORO-5-PHENYL-PYRIMIDINE ISO 9001：2015 REACH
CBNumber:
CB4428455
Molecular Formula:
C10H7ClN2
Molecular Weight:
190.63
MDL Number:
MFCD04035567
MOL File:
22536-62-5.mol
MSDS File:
SDS
Last updated:2026-05-28 03:03:02
Product description Number Pack Size Price
2-Chloro-5-phenylpyrimidine 98% OR938765 100mg $21
2-Chloro-5-phenylpyrimidine 98% OR938765 250mg $24
2-Chloro-5-phenylpyrimidine 98% OR938765 1g $64
2-Chloro-5-phenylpyrimidine 98% OR938765 5g $313
2-Chloro-5-phenylpyrimidine 98% OR938765 25g $1445
Request For Quotation

2-CHLORO-5-PHENYL-PYRIMIDINE Properties

Melting point 131-133 °C
Boiling point 369.9±21.0 °C(Predicted)
Density 1.245±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -1.71±0.22(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933599590

2-CHLORO-5-PHENYL-PYRIMIDINE price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR938765 2-Chloro-5-phenylpyrimidine 98% 22536-62-5 100mg $21 2026-06-04 Buy
Apolloscientific OR938765 2-Chloro-5-phenylpyrimidine 98% 22536-62-5 250mg $24 2026-06-04 Buy
Apolloscientific OR938765 2-Chloro-5-phenylpyrimidine 98% 22536-62-5 1g $64 2026-06-04 Buy
Apolloscientific OR938765 2-Chloro-5-phenylpyrimidine 98% 22536-62-5 5g $313 2026-06-04 Buy
Apolloscientific OR938765 2-Chloro-5-phenylpyrimidine 98% 22536-62-5 25g $1445 2026-06-04 Buy
Product number Packaging Price Buy
OR938765 100mg $21 Buy
OR938765 250mg $24 Buy
OR938765 1g $64 Buy
OR938765 5g $313 Buy
OR938765 25g $1445 Buy

2-CHLORO-5-PHENYL-PYRIMIDINE Chemical Properties,Uses,Production

Application

2-Chloro-5-phenylpyrimidine can be used as an organic synthesis intermediate. It can be prepared by reacting 5-bromo-2-chloropyrimidine with Ph3In as a reactant, or by reacting 5-bromo-2-chloropyrimidine with phenylboronic acid via the Suzuki reaction.

Synthesis

5-Bromo-2-chloropyrimidine

32779-36-5

Phenylboronic acid

98-80-6

2-CHLORO-5-PHENYL-PYRIMIDINE

22536-62-5

General procedure: 5-bromo-2-chloropyrimidine (1 eq.), phenylboronic acid (1.1 eq.), Na2CO3 (1.1 eq.) and H2O (5 mL) were added to a round bottom flask, followed by catalyst (2 mol%). The reaction mixture was stirred at 45 °C until the reaction was complete. Upon completion of the reaction, the reaction mixture was diluted with water and the product was extracted with ethyl acetate. The ethyl acetate extract was filtered through a bed of diatomaceous earth and subsequently analyzed by GC. Retention times were verified using standards of 5-bromo-2-chloropyrimidine and 2-chloro-5-phenylpyrimidine to confirm product generation. The ethyl acetate extract was concentrated and purified by silica gel column chromatography using a solvent mixture of hexane and ethyl acetate as eluent to give 2-chloro-5-phenylpyrimidine. The product was characterized by NMR, GC-MS and UPLC analysis.

References

[1] Journal of Heterocyclic Chemistry, 2008, vol. 45, # 4, p. 1077 - 1081
[2] Journal of Molecular Catalysis A: Chemical, 2013, vol. 371, p. 118 - 124
[3] European Journal of Medicinal Chemistry, 2018, vol. 150, p. 30 - 38
[4] Patent: WO2004/22556, 2004, A1. Location in patent: Page 16-17

2-CHLORO-5-PHENYL-PYRIMIDINE synthesis

100-59-4
32779-36-5
22536-62-5
Synthesis of 2-CHLORO-5-PHENYL-PYRIMIDINE from PHENYLMAGNESIUM CHLORIDE and 5-Bromo-2-chloropyrimidine

2-CHLORO-5-PHENYL-PYRIMIDINE Preparation Products And Raw materials

Raw materials

1-Methyl-5-phenyl-2(1H)-pyrimidinone 5-PhenylpyriMidin-2(1H)-one Triphenylindium PHENYLMAGNESIUM CHLORIDE Phenylboronic acid
TRIBUTYLPHENYLTIN Benzene 5-Bromo-2-chloropyrimidine Water Sodium carbonate

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Preparation Products

2-CHLORO-5-PHENYL-PYRIMIDINE Suppliers

Global( 68)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 14035 58
career henan chemical co 		+86-0371-86658258 factory@coreychem.com China 29780 58
Dideu Industries Group Limited 		+8617392712697 1022@dideu.com China 29094 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53799 58
Nanjing Moldeep Biochemical Co., Ltd. 		+86-25-58282389 +86-17351037455 inquiries@moldeep.com China 19999 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
ROSEWA HOLDING GROUP CO.,LIMITED 		+86-023-62871537 sales@rosewachem.com China 2812 58
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7883 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
career henan chemical co 		58
Dideu Industries Group Limited 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Nanjing Moldeep Biochemical Co., Ltd. 		58
Amadis Chemical Company Limited 		58
ROSEWA HOLDING GROUP CO.,LIMITED 		58
Tetranov Biopharm 64
Nanjing Chemlin Chemical Co., Ltd 64

View Lastest Price from 2-CHLORO-5-PHENYL-PYRIMIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-5-PHENYL-PYRIMIDINE pictures 2026-08-20 2-CHLORO-5-PHENYL-PYRIMIDINE
22536-62-5
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-CHLORO-5-PHENYL-PYRIMIDINE pictures 2020-01-09 2-CHLORO-5-PHENYL-PYRIMIDINE
22536-62-5
 $1.00 1KG 95-99% 1ton Career Henan Chemical Co

2-CHLORO-5-PHENYL-PYRIMIDINE Spectrum

2-CHLORO-5-PHENYL-PYRIMIDINE(22536-62-5)1HNMR

22536-62-5(2-CHLORO-5-PHENYL-PYRIMIDINE)Related Search:

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2-CHLORO-5-PHENYL-PYRIMIDINE 2-Chloro-5-phenyl-pyridimine PyriMidine,2-chloro-5-phenyl- 2-CHLORO-5-PHENYL-PYRIMIDINE ISO 9001：2015 REACH 22536-62-5 pyrimidine Heterocycle-Pyrimidine series pharmacetical