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6-Carboxyfluorescein diacetate

CAS No.
3348-03-6
Chemical Name:
6-Carboxyfluorescein diacetate
Synonyms
3TFA;6-CFDA;NSC3410;6-FAM DA;3TFA ≥NSC 3410;NSC-3410;6-fam(Ac2);~95% (HPLC);Abafungin &ge
CBNumber:
CB4669199
Molecular Formula:
C25H16O9
Molecular Weight:
460.39
MDL Number:
MFCD00036871
MOL File:
3348-03-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:56

6-Carboxyfluorescein diacetate Properties

Melting point 152–153°C
Boiling point 701.6±60.0 °C(Predicted)
Density 1.57±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble
pka 6.4(at 25℃)
form Solid
color Light yellow or off-white solid
PH Range Weak green ' uorescence (6.0) to strong green ' uourescence (7.2)
λmax <300nm
Major Application Fluorescent probes, detecting cells, microorganisms, yeasts, antifungal agent, antibacterials agent
Biological Applications Analyzing/detecting cells;counting/ detecting/evaluating microorganisms;detecting/ measuring bacteria;quantifying adhesion of tumor cells to endothelial monolayers; measuring gas (carbon dioxide or ammonia) concentration in body luids; monitoring intracellular nitric oxide production;screening xenobiotic phloem mobility in plants; , studying low-density lipoprotein (LDL)/cholesterol metabolism;apoptosis assay;method for antifungal susceptibility testing; , as a substrate for measuring esterase activity
InChI 1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)
InChIKey QMOGCCYGOPYYNT-UHFFFAOYSA-N
SMILES CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1
CAS DataBase Reference 3348-03-6(CAS DataBase Reference)
UNSPSC Code 12171500
NACRES NA.47

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
10-21
HS Code  29322090
Storage Class 11 - Combustible Solids

6-Carboxyfluorescein diacetate price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C5041 6-Carboxyfluorescein diacetate ≥95% (HPLC) 3348-03-6 25 mg $115 2026-04-30 Buy
Sigma-Aldrich C5041 6-Carboxyfluorescein diacetate ≥95% (HPLC) 3348-03-6 100 mg $180 2026-04-30 Buy
TCI Chemical C3710 6-Carboxyfluorescein Diacetate 3348-03-6 20MG $51 2026-04-30 Buy
TCI Chemical C3710 6-Carboxyfluorescein Diacetate 3348-03-6 100MG $179 2026-04-30 Buy
Usbiological 269614 6-Carboxyfluoresceine diacetate Asreported 3348-03-6 50mg $319 2026-06-03 Buy
Product number Packaging Price Buy
C5041 25 mg $115 Buy
C5041 100 mg $180 Buy
C3710 20MG $51 Buy
C3710 100MG $179 Buy
269614 50mg $319 Buy

6-Carboxyfluorescein diacetate Chemical Properties, Uses, Production

Description

6-Carboxyfluorescein diacetate is a membrane-permeant prodrug of 6-Carboxyfluorescein, which has been used to differentiate viable cells from apoptotic cells.

Uses

6-CARBOXYFLUORESCEIN DIACETATE is used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin

Uses

6-Carboxyfluorescein Diacetate is a fluorescent polyanionic probe used to detect changes intracellular pH. In addition, 6-Carboxyfluorescein Diacetate derivatives can be used as staining agents for flow cytometry to visualize cells undergoing apoptosis or necrosis.

Excitation / Emission Maximum

553 nm/575 nm

6-Carboxyfluorescein diacetate Preparation Products And Raw materials

Global Suppliers ( 185)
Supplier Tel Email Country ProdList Advantage
Shanghai Annengjian Biomedical Technology Co., LTD 021-68781987 13818305065 sales@energybiopharma.com China 788 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Nanjing Search Biotech Co., Ltd +86-025-81682922 +86-13515111588 sales@searchbio.com.cn China 137 68
Nanjing Habo Medical Technology Co., Ltd. 13376080562 13376090521 sales@habotech.com China 724 60
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6743 52
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Okeanos Tech Co,. Ltd. 010-62651721 18610486005 minghui.yu@okeanos.com.cn China 495 60
Nanjing Asian Chemical Co., Ltd. +86 (25) 82263158 China 262 60
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58

View Latest Price from 6-Carboxyfluorescein diacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-CFDA pictures 2026-09-13 6-CFDA
3348-03-6
$30.00 10g TargetMol Chemicals Inc.
6-CARBOXYFLUORESCEIN DIACETATE pictures 2026-09-07 6-CARBOXYFLUORESCEIN DIACETATE
3348-03-6
1kg 99%min 2000KGS HANGZHOU HAILAN CHEMICAL CO.,LTD.
6-CFDA pictures 2026-08-08 6-CFDA
3348-03-6
$30.00 10g TargetMol Chemicals Inc.
  • 6-CFDA pictures
  • 6-CFDA
    3348-03-6
  • $30.00
  • TargetMol Chemicals Inc.
  • 6-CFDA pictures
  • 6-CFDA
    3348-03-6
  • $30.00
  • TargetMol Chemicals Inc.
BIOCHEMIKA, FOR FLUORESCENCE, ≥90.0% (HPLC) ~95% (HPLC) 6-Carboxy-di-O-acetylfluorescein, 6-CFDA 3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid 3',6'-Diacetoxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid 3-Oxo-3',6'-diacetoxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid 6-CARBOXY-DI-O-ACETYLFLUORESCEIN 6-CARBOXYFLUORESCEINE DIACETATE 6-CFDA 6-FAM DIACETATE 3',6'-diacetoxy-1-keto-spiro[isobenzofuran-3,9'-xanthene]-5-carboxylic acid 3',6'-diacetyloxy-1-oxo-spiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid 3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid 6-Carboxyfluorescein diacetate,6-CFDA, 6-Carboxy-di-O-acetylfluorescein 6-FAM DA 3',6'-Diacetoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid 6-CFDA [6-Carboxyfluorescein diacetate] Spiro[phthalan-1,9′-xanthene]-6-carboxylic Acid, 3′,6′-dihydroxy-3-oxo-, Diacetate Terephthalic acid, (3,6,9-trihydroxyxanthen-9-yl)-, Γ-lactone, diacetate 6-carboxy' Uoresceindiacetate 2-Amino-5-nitropyridine &ge -tert-butoxy)-guanidino]-pentanoic acid &ge 1-[3-Amino-4-(methylamino)phenyl]ethanone &ge Phe-Leu-OH &ge 3-(4-Chlorophenyl)Pyrrolidine Oxalate &ge 3-Methoxybenzamidine hydrochloride &ge (2S)-Boc-2-amino-6-(3,5-diformyl-4-methyl-4H-pyridin-1-yl)-hexanoic acid tert-butyl ester &ge Fmoc-L-b-glutamic acid 5-tert-butyl ester &ge 5-(Bromomethyl)isoquinoline &ge 4-Bromomethyl-5-methyl-1,3-dioxol-2-one &ge Boc-1-aminomethyl-cyclopentane carboxylic acid &ge 6-Bromo-3-chloro-1H-indazole &ge 5-(Bromomethyl)-1-methyl-1H-indazole hydrobromide &ge Acetyl-L-threonine methyl ester &ge (2-Amino-2-phenylethyl)dimethylamine &ge 3-Chloro-5-hydroxy-benzoic acid &ge 6-(Hydroxymethyl)-1-methylindazole &ge 5-Hydroxytoluene-2-boronic acid &ge Boc-O-benzyl-L-serinol &ge 3TFA Isocyano(3-methoxyphenyl)methyl-4-methylphenyl sulfone &ge Boc-(S)-3-amino-3-(2-nitrophenyl)propionic acid &ge Isoquinoline-5-carbothioic acid amide &ge L-Cystine bis(tert-butyl ester) dihydrochloride &ge 2-Methyl-2H-indazol-5-ylamine &ge Ethyl [1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate &ge Methyl 1-methylindazole-4-carboxylate &ge 5-Methoxy-1H-indazole-3-carboxylic acid &ge 4-Chloro-2-anisidine hydrochloride &ge 6-Chloroimidazo[1,2-b]pyridazine-2-carboxylic acid &ge 2,6-Dimethylpyridin-4-ylamine &ge Na-Z-L-lysine benzyl ester benzenesulfonate salt &ge 5-Hydroxymethylisoquinoline &ge 4-(2-Methoxyphenoxy)Benzylamine Hydrochloride &ge Ethyl 2-Bromo-5-chlorothiazole-4-carboxylate &ge 4-Bromo-5-Methyl-1H-indazole &ge 1-Methyl-1H-indazole-7-carbaldehyde &ge Acetyl-g-aminobutyric acid &ge