ChemicalBook >> CAS DataBase List >>5-CFDA, AM

5-CFDA, AM

CAS No.
124412-00-6
Chemical Name:
5-CFDA, AM
Synonyms
CFDA-AM;5-CFDA, AM;5-Fam(Ac)2-AM;YDBUJZYYYBVSEF-UHFFFAOYSA-N;5-CFDA-AM, 90%, single isomer;CFDAAMCarboxyfluoresceindiacetateAMester;5-CARBOXYFLUORESCEIN DIACETATE, ACETOXYMETHYL ESTER;5-Carboxyfluorescein diacetate acetoxylmethyl ester;5-Carboxyfluorescein diacetate (acetyloxy)methyl ester;5-(AND-6)-CARBOXY SNARF(R)-1, ACETOXYMETHYL ESTER, ACETATE
CBNumber:
CB6108173
Molecular Formula:
C28H20O11
Molecular Weight:
532.45
MDL Number:
MFCD00467519
MOL File:
124412-00-6.mol
MSDS File:
SDS
Last updated:2025-08-05 17:23:11
Product description Number Pack Size Price
5-CFDA-AM 99.81% CS-0129181 5mg $303
5-CFDA-AM 99.81% CS-0129181 10mg $487
5-CFDA-AM C8358 1mg $117
5-CFDA-AM C8358 5mg $252
5-CFDA-AM C8358 10mg $405
More product size

5-CFDA, AM Properties

Boiling point 737.0±60.0 °C(Predicted)
Density 1.51±0.1 g/cm3(Predicted)
form Solid
color White to off-white
Appearance Solid Powder

5-CFDA, AM price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0129181 5-CFDA-AM 99.81% 124412-00-6 5mg $303 2026-06-04 Buy
ChemScene CS-0129181 5-CFDA-AM 99.81% 124412-00-6 10mg $487 2026-06-04 Buy
ApexBio Technology C8358 5-CFDA-AM 124412-00-6 1mg $117 2026-05-06 Buy
ApexBio Technology C8358 5-CFDA-AM 124412-00-6 5mg $252 2026-05-06 Buy
ApexBio Technology C8358 5-CFDA-AM 124412-00-6 10mg $405 2026-05-06 Buy
Product number Packaging Price Buy
CS-0129181 5mg $303 Buy
CS-0129181 10mg $487 Buy
C8358 1mg $117 Buy
C8358 5mg $252 Buy
C8358 10mg $405 Buy

5-CFDA, AM Chemical Properties,Uses,Production

Description

5-carboxyfluorescein diacetate acetoxymethyl ester is a cell-permeant fluorogenic esterase substrate. It can be converted by nonspecific esterases of living cells from a membrane-permeable, nonpolar, nonfluorescent substance to a polar product CF, indicating the integrity of the plasma membrane.

Uses

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell[1].

References

[1] Elena Gorokhova, et al. A comparison of TO-PRO-1 iodide and 5-CFDA-AM staining methods for assessing viability of planktonic algae with epifluorescence microscopy. J Microbiol Methods. 2012 Jun;89(3):216-21. DOI:10.1016/j.mimet.2012.03.005

5-CFDA, AM Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CARBOXYFLUORESCEIN DIACETATE, ACETOXYMETHYL ESTER 5-CFDA, AM 5-(AND-6)-CARBOXY SNARF(R)-1, ACETOXYMETHYL ESTER, ACETATE 5-Carboxyfluorescein diacetate acetoxylmethyl ester 3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid (acetyloxy)methyl ester 5-CFDA-AM [5-carboxyfluorescein diacetate, acetoxymethyl ester] YDBUJZYYYBVSEF-UHFFFAOYSA-N 5-CFDA-AM, 90%, single isomer CFDA-AM CFDAAMCarboxyfluoresceindiacetateAMester 5-Carboxyfluorescein diacetate (acetyloxy)methyl ester Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-bis(acetyloxy)-3-oxo-, (acetyloxy)methyl ester 5-Fam(Ac)2-AM 124412-00-6 C28H20O11